Biofilms are the slimy cities some microbes form when they invade a surface. Conventional cleaning products are generally good at breaking up biofilms. But they tend to be harsh on the environment. And while natural products are a good alternative, it takes multiple enzymes to break up the strong polymers that make bacteria stick. But researchers are confident that a natural solution does exist. One team searched the forest floor in the Netherlands for microbes that might produce an all-in-one biofilm-busting enzyme. To coax those microbes out, they enriched forest litter with an especially tough biopolymer produced by forest bacteria: Acidobacteria. Microbes that could thrive in that environment likely produced enzymes strong enough to degrade the biopolymer blend. Analyses indicated the predominance of four bacterial phyla. More importantly, they revealed the main type of enzyme these bacteria secreted: glycoside hydrolases. Producing these enzymes could lead to cleaner surfaces in the chemical, pharmaceutical, food industries, and other industrial sectors and could help reduce the environmental burden introduced by harsh cleaning products.