Biological Sciences - Articleposted 2024-09-04 00:11:03
Combining same-target drugs exhibits additive efficacy with minimal toxicity
Shao-Qing Cai, Yi Wang, Feng Xu, Qian Zhao, Hong-Fu Li, Weijing Cai, Jing-Rong Cui, and 9 more authors
Posted
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Articleposted 2024-08-29 18:49:40
Novel Cisplatin-Magnetosome Complex Shows Enhanced Antitumor Activity via Hyperthermia
M. Carmen Jiménez-López, Ana Carolina Moreno-Maldonado, Natividad Martín-Morales, Francisco O’Valle, M. Ricardo Ibarra, Gerardo F. Goya, Ignacio J. Molina
Under Revision
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Articleposted 2024-08-23 12:27:36
Construction and Preclinical evaluation of BCL3-Degrading PROTACs for Enhanced Colorectal Cancer Therapy
Jing Zhao, Bo Bi, Yongshu Li, Shangbo Zhou, Qiang Wang, Heng-Xing Chen, Zihang Li, and 12 more authors
Under Review
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Articleposted 2024-08-19 09:05:59
Synthesis of selective BCL-XL PROTAC and potent antitumor activity in glioblastoma
Jinlong Yin, Biao Sun, Meichen Liu, Yue Zhang, Rui Niu, Xinyu Li, Jiefei Wang, and 1 more authors
Under Review
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Articleposted 2024-05-20 09:37:38
Selectivity analysis of diaminopyrimidine-based inhibitors of MTHFD1, MTHFD2 and MTHFD2L
Vibhu Jha, Leif A. Eriksson
Under Review
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Articleposted 2024-05-02 19:09:30
CDK9 recruits HUWE1 E3 ligase to degrade RARα in a kinase independent manner and offers therapeutic opportunities for cutaneous T-cell lymphoma
Ying Lu, Chen-Hui Luo, Li-Hong Hu, Jie-Yang Liu, Li XIA, Li Zhou, Ren-Hong Sun, and 4 more authors
Under Review
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Articleposted 2024-04-03 12:09:24
Expression of c-erb-B2 oncoprotein as a neoantigen strategy to repurpose anti-neu antibody therapy in a model of melanoma
Emmanuel M. Gabriel, Brian Necela, Deborah Bahr, Sneha Vivekanandhan, Barath Shreeder, Sanjay Bagaria, Keith L. Knutson
Under Review
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Articleposted 2024-03-15 11:29:46
Targeting ZAKα Interactions and Ribosomes with Novel peptides: The role of ZAKα in Mitochondrial Function and Cancer Cell Proliferation
Jaw-Ji Yang, Ying-Chang Hsu, Yang-Shan Yeh
Under Review
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Articleposted 2024-01-23 05:12:02
Small-molecule RAS/RAF Binding Inhibitors Allosterically Disrupt RAF Conformation and Exert Efficacy Against a Broad Spectrum of RAS-driven Cancers
Fumi Shima, Yoko Yoshikawa, Yoshiteru Makino, Hirokazu Kubota, Takashi Kawamura, Shigeyuki Matsumoto, Hitomi Yuki, and 11 more authors
Under Review
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Articleposted 2023-12-21 21:30:50
Nanonoscapine: A Promising Treatment for Prostate Cancer Through Targeting GLI1 and BAX Expression
Mohammad Hossein Derakhshan Nazari, Ronak Heidarian, Mina Masoudnia, Rana Askari Dastjerdi, Parnian Ghaedi Talkhounche, Sara Taleahmad
Published
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