DAF-16/FOXO and HLH-30/TFEB comprise a cooperative regulatory axis controlling tubular lysosome induction in C. elegans
Distinct recognition of mutant huntingtin aggregates by autophagy receptor SQSTM1/p62 versus optineurin has differential effects on cell survival
The loss of OPA1 accelerates intervertebral disc degeneration and osteoarthritis in aged mice
ATG5-mediated keratinocyte ferroptosis promotes M1 polarization of macrophages to aggravate UVB-induced skin inflammation
Schwann cell-specific ablation of Beclin 1 impairs peripheral myelination and leads to a progressive motor and sensory neuropathy
Transcriptional changes impact hepatic proteome in autophagy-impaired liver
BECLIN1 is essential for intestinal homeostasis
Crosstalk among TFEB, the autophagy lysosomal pathway and ROS derived from damaged mitochondria in NaAsO2-induced auditory senescent cells
Karyoptosis mediates cell death and neurodegeneration upon proteotoxic stress
Thioredoxin-1 decreases alpha-synuclein induced by MPTP through promoting autophagy-lysosome pathway