Background: Rhabdomyolysis is a syndrome characterized by muscle necrosis and release of intracellular muscle components into systemic circulation. Common causes include high-intensity exercise, crush injury, high fever, drugs, and inflammation. Here, we have a prospective observational study of collective rhabdomyolysis caused by infrequent short-term high-intensity exercise.
Methods: The patients were a group of adolescents, of which 35 developed severe muscle pain and dark-brown urine after military training and were hospitalized, while others developed mild symptoms and returned to school after relief of symptoms following outpatient treatment. We used SPSS 13.0 to calculate the sample mean and standard deviation of various laboratory indicators.
Results: The average serum creatinine kinase was 33532.43±39982.95 U/L, and average serum lactate dehydrogenase was 1816.97±1413.59 U/L at the time of admission. When they were discharged, the above two indicators became 1902.2±1366.37 U/L and 210.31±61.27 U/L. Signs and symptoms improved in all patients after the intravenous injection of average 5000ml within 5.5 days of normal saline and balance solution and implementation of a bed rest regimen. No complications occurred (e.g., acute renal failure, disseminated intravascular coagulation, or electrolyte imbalance). All patients were relieved of symptoms and discharged after an average of 5.47 days of hospitalization. Of these, 20 patients were prescribed medical treatment and returned to the clinic within 1 month after discharge.
Conclusions: Suddenly and dramatically increase the amount of exercises in a short period of time is easy to cause rhabdomyolysis. We hope that everyone can avoid similar situations.