Low pH Hypromellose (Taffix™) nasal powder spray reduced SARS-CoV-2 infection rate post mass-gathering event at a highly endemic community: An observational prospective open label user survey
Introduction: The city of Bney Brak, Israel, (population 210,000 mostly ultra-orthodox Jews) tops Israel list of COVID-19 infection rate and mortality. In mid-September before the Jewish New Year (an intensive two day gathering for prayers) PCR positivity rates were 17.6% and those climbed to 28.1% two weeks later
Taffix - is an innovative nasal powder inhaler that creates a protective gel layer over the nasal mucosa and effectively blocks viruses from infecting the nasal cells. Taffix is approved for use in Europe and Israel. In vitro studies demonstrated that Taffix blocks viruses (including SARS- CoV-2) from infecting human cells (<99% ). It is well established that the nose is the main gateway of SARS- CoV-2 to the body. Taffix™ was developed as an additional virus protective tool beyond the currently recommended preventive measures.
Methods: In a prospective users survey, 243 members of a Jewish ultra-orthodox synagogue community in Bney Brak that participated in the two days holidays prayers (7 hours spent daily in the synagogue) were followed up for the following 14 days to measure the effect of Taffix in this potentially “super spread” ( post mass gathering) event . 83 collected and used Taffix throughout Rosh Hashana prayers and for the following two weeks (intention to treat group, ITT) . 81 of them used it regularly as instructed ( per protocol, PP) while two used it rarely if at all. The remaining 160 did not use Taffix .
Results: At the end of the two weeks follow up - in the ITT population, 2/83 (2.4%) of the Taffix users and 16/160 (10%) of the Taffix non users were infected. The odds ratio for SARS-CoV-2 infection in Taffix users were 0.22 (0.05-0.99, Mid P exact =0.028), a reduction of 78% (95%CI 1%-95%) in odds of infection. No side effects were reported.
Conclusion: We suggest that Taffix can be an additional powerful tool against COVID19 spread. To our knowledge this is the first time that any measure to prevent infection in SARS-CoV-2 virus, beyond the use of masks. was proven effective.
Figure 1
Due to technical limitations, full-text HTML conversion of this manuscript could not be completed. However, the latest manuscript can be downloaded and accessed as a PDF.
Due to its specific particle size Taffix does not reach the airways or lungs, We have heard many anecdotal reports from Taffix users of an improvement in their nasal allergic symptoms and sinusitis but have not researched this yet.
Cellulose is a polysacharide and plysacharides on hydrolysis get converted into glucose which has antiviral properties. Glucose is a white crystalline powder. The white color is a combination of seven different colors with different energy levels. It represent electromagnetic waves with seven different components. Glucose carries electromagnetism waves which can detect the presence of pathogenic organisms and kill them within a split second.
Cellulose on hydrolysis gets converted into glucose which carries six water molecules in ionic state and they can kill the corona viruses by direct contact within a split second.
I purchased a bottle on amazon.de, Regards.
As an airline pilot, wearing a mask in flight is a real hindrance. It leads to misunderstandings and more, in case of a depressurisation, I doubt anyone would think about removing his mask before donning the oxygen mask. I use Taffix at all time when working and when socialising. Of course it is hard to say if it really works.....proving the contrary or trying to, would be exposing oneself to a high virus load. Maybe not......:)) The scientific evidence seems to be there and a year into the crisis and 4 months of using Taffix......I am still virus free.......without really limiting myself other than washing my hands and keeping my distance. Until I get vaccinated, this is certainly the best product to protect oneself without the impression of having one’s freedom curtailed.........too much. I am always amazed by the fact it is always the Israelis who come up with ideas out of the box. What a clever people.
Posted 20 Jan, 2021
Low pH Hypromellose (Taffix™) nasal powder spray reduced SARS-CoV-2 infection rate post mass-gathering event at a highly endemic community: An observational prospective open label user survey
Posted 20 Jan, 2021
Introduction: The city of Bney Brak, Israel, (population 210,000 mostly ultra-orthodox Jews) tops Israel list of COVID-19 infection rate and mortality. In mid-September before the Jewish New Year (an intensive two day gathering for prayers) PCR positivity rates were 17.6% and those climbed to 28.1% two weeks later
Taffix - is an innovative nasal powder inhaler that creates a protective gel layer over the nasal mucosa and effectively blocks viruses from infecting the nasal cells. Taffix is approved for use in Europe and Israel. In vitro studies demonstrated that Taffix blocks viruses (including SARS- CoV-2) from infecting human cells (<99% ). It is well established that the nose is the main gateway of SARS- CoV-2 to the body. Taffix™ was developed as an additional virus protective tool beyond the currently recommended preventive measures.
Methods: In a prospective users survey, 243 members of a Jewish ultra-orthodox synagogue community in Bney Brak that participated in the two days holidays prayers (7 hours spent daily in the synagogue) were followed up for the following 14 days to measure the effect of Taffix in this potentially “super spread” ( post mass gathering) event . 83 collected and used Taffix throughout Rosh Hashana prayers and for the following two weeks (intention to treat group, ITT) . 81 of them used it regularly as instructed ( per protocol, PP) while two used it rarely if at all. The remaining 160 did not use Taffix .
Results: At the end of the two weeks follow up - in the ITT population, 2/83 (2.4%) of the Taffix users and 16/160 (10%) of the Taffix non users were infected. The odds ratio for SARS-CoV-2 infection in Taffix users were 0.22 (0.05-0.99, Mid P exact =0.028), a reduction of 78% (95%CI 1%-95%) in odds of infection. No side effects were reported.
Conclusion: We suggest that Taffix can be an additional powerful tool against COVID19 spread. To our knowledge this is the first time that any measure to prevent infection in SARS-CoV-2 virus, beyond the use of masks. was proven effective.
Figure 1
Due to technical limitations, full-text HTML conversion of this manuscript could not be completed. However, the latest manuscript can be downloaded and accessed as a PDF.
Due to its specific particle size Taffix does not reach the airways or lungs, We have heard many anecdotal reports from Taffix users of an improvement in their nasal allergic symptoms and sinusitis but have not researched this yet.
Cellulose is a polysacharide and plysacharides on hydrolysis get converted into glucose which has antiviral properties. Glucose is a white crystalline powder. The white color is a combination of seven different colors with different energy levels. It represent electromagnetic waves with seven different components. Glucose carries electromagnetism waves which can detect the presence of pathogenic organisms and kill them within a split second.
Cellulose on hydrolysis gets converted into glucose which carries six water molecules in ionic state and they can kill the corona viruses by direct contact within a split second.
I purchased a bottle on amazon.de, Regards.
As an airline pilot, wearing a mask in flight is a real hindrance. It leads to misunderstandings and more, in case of a depressurisation, I doubt anyone would think about removing his mask before donning the oxygen mask. I use Taffix at all time when working and when socialising. Of course it is hard to say if it really works.....proving the contrary or trying to, would be exposing oneself to a high virus load. Maybe not......:)) The scientific evidence seems to be there and a year into the crisis and 4 months of using Taffix......I am still virus free.......without really limiting myself other than washing my hands and keeping my distance. Until I get vaccinated, this is certainly the best product to protect oneself without the impression of having one’s freedom curtailed.........too much. I am always amazed by the fact it is always the Israelis who come up with ideas out of the box. What a clever people.
Thank you so much !! As physicians we actually "live" for people's feed back such as this one. Keep safe !! Will share with the team.
Dalia Megiddo
replied on 25 February, 2021
Thank you so much !! As physicians we actually "live" for people's feed back such as this one. Keep safe !! Will share with the team.