Background: Chronic kidney disease (CKD) patients are a large population and of significant importance. Except for having an underlying disease, they have some other risk factors, for example, old age, impaired immune function, and other comorbidities that make them more susceptible to the new SARS-COV2 infection.
Methods: As data on CKD patients with SARS-CoV-2 Infection is limited, we decided to carry out a cross-sectional study at Labbafinezhad Hospital on 78 CKD patients with approved COVID-19 infection either on dialysis or not. We have also incorporated CKD patients with kidney transplant history.
Results: The mean age of the patients was 64.04 years, including 53 women and 25 men. Among all symptoms, dyspnea (19.2%) was the most prevalent one. Laboratory data analysis shows an increase in LDH, Creatinine, and ESR and CRP levels. The most common finding on chest CT-Scan was bilateral ground-glass opacity detected in 31 (86.1%) patients, followed by pleural effusion (12.8%) and atelectasis (19%). Among included patients, 53 (74.6%) had hypoxia (o2 saturation 94% and lower), 47 (81%) had tachypnea (respiratory rate over 16) and 9 (23.1%) had some reduction in the level of consciousness (GCS lower than 15).
Conclusion: Due to the important effect of underlying medical conditions on the outcome of COVID-19 patients, evaluation of clinical manifestations, radiologic findings, laboratory data, and outcome of COVID-19 patients with chronic kidney disease is important to establish a perspective for physicians to manage CKD patients.