Case report
|
Age (years)
|
Gender
|
Ethnicity
|
Site of primary MCC
|
Treatment of primary site lesion
|
Time between initial diagnosis or therapy and metastasis (months)
|
Clinical presentation
|
Treatment of metastasis
|
Outcome (at the time of report)
|
Time between metastatic disease and death
|
Canales et al. (1992) [17]
|
67
|
M
|
Unknown
|
Right gluteal region
|
Surgical resection and
local RT
|
11
|
Generalized fatigue,
orthostatic symptoms,
melena
|
Total gastrectomy,
CP,
VCR,
DOX
|
Receiving CT
|
NA
|
Krasagakis et al. (1997) [18]
|
81
|
M
|
Unknown
|
Right hand (5th finger)
|
Surgical resection,
axillary lymph
node dissection,
RT, CT
|
12
|
GI bleeding
|
Surgical resection of gastric mass
|
Deceased for metastatic disease
|
3 weeks
|
Idowu et al. (2003) [19]
|
79
|
F
|
Unknown
|
Right inguinal
|
Surgical resection,
RT, CT
|
48
|
Light-headedness, melena,
27.2-kg weight loss within
6 months
|
Not described
|
Deceased for metastatic disease
|
4 months
|
Cubiella et al. (2004)* [20]
|
74
|
M
|
Unknown
|
Right retroauricolar
|
Surgical resection, CT
|
23
|
Hematemesis, melena
|
Surgical resection of gastric mass
|
Deceased for metastatic disease
|
2 months
|
Shalhub et al. (2004) [21]
|
62
|
M
|
Unknown
|
Right neck
|
Surgical resection
|
72
|
Persistent fevers, jaundice
|
CBDCA, EPEG
|
Deceased for metastatic disease
|
1 month
|
Li and Liu (2004) [22]
|
46
|
M
|
Caucasian
|
Left preauricular
|
Surgical resection,
RT, CT
|
8
|
Melena
|
CDDP, DOX
|
Receiving CT
|
NA
|
Hizawa et al. (2007)* [23]
|
85
|
F
|
Japanese
|
Right eyelid
|
Surgical resection, RT
|
20
|
Vomit
|
Palliative care
|
Deceased for metastatic disease
|
2 months
|
Wolov et al. (2009) [24]
|
80
|
M
|
Unknown
|
Right upper
extremity
|
Surgical resection, RT
|
24
|
Progressive fatigue, syncope,
melena
|
Combined
CT-RT with
4 cycles of CBDCA
|
Deceased
|
Unknown
|
Rosa et al. (2010) [25]
|
72
|
F
|
Unknown
|
Right inguinal
|
Surgical resection,
RT, CT
|
24
|
Light-headedness, epigastric
pain, hematemesis, weight
loss
|
Billroth II resection,
2 cycles of adjuvant
CT
|
Alive after 24 months of
follow-up
|
NA
|
Temiz et al. (2010) [26]
|
75
|
M
|
Unknown
|
Left thigh
|
Surgical resection
|
10
|
Perforated duodenal ulcer
|
Incidental resection of
gastric mass
|
Deceased
|
17 months
|
Syal et al. (2012) [27]
|
68
|
M
|
Unknown
|
Left leg
|
Surgical resection,
RT, CT
|
Unknown
|
Melena, fatigue, exertional
dyspnea, epigastric pain
|
CT, RT
|
Receiving RT
|
NA
|
Parikh et al. (2014) [28]
|
60
|
M
|
Hispanic
|
Right inguinal
|
CT, RT
|
4
|
Fatigue, weakness, black-colored
stools
|
3 cycles of
CT
|
Unknown
|
Unknown
|
Capella et al. (2014) [29]
|
72
|
M
|
Unknown
|
Unknown
|
NA
|
2
|
Epigastric pain and 9-kg weight loss within 1 month.
|
Total gastrectomy and splenectomy, EPEG, CDDP
|
Deceased for metastatic disease
|
2 months
|
Santos-Juanes et al. (2016) [30]
|
52
|
M
|
Unknown
|
Right thigh
|
Surgical resection, right inguinal lymph nodes dissection, RT, CBDCA, EPEG
|
24
|
Anaemia
|
CT
|
Deceased for metastatic disease
|
6 months
|
Pedrazzani et al. (2016) [31]
|
70
|
F
|
Unknown
|
Left knee
|
Surgical resection
|
19
|
Asymptomatic
|
No adjuvant therapy
|
Alive after 12 months follow-up
|
NA
|
Hu et al. (2016) [16]
|
92
|
M
|
Caucasian
|
Left upper
extremity
|
Surgical resection, RT
|
15
|
Fatigue, early satiety, syncope,
melena, 9-kg weight loss
within 1 month
|
Palliative care
|
Deceased for metastatic disease
|
5 weeks
|
Hulstaert et al. (2016) [32]
|
77
|
M
|
Caucasian
|
Abdominal wall (left sided paraumbilical)
|
Surgical resection
|
36
|
Melena
|
CBDCA, EPEG (refused surgery)
|
Receiving CT
|
NA
|
Trivedi et al. (2017) [33]
|
52
|
M
|
Vietnamese
|
Left gluteal region
|
Biopsy, RT
|
36
|
Ulcerated skin lesion, gastric perforation during CT
|
CDDP, EPEG, emergency wedge gastrectomy
|
Alive after 18 months follow-up
|
NA
|
Ha et al. (2018) [34]
|
82
|
M
|
Unknown
|
Left gluteal region
|
Surgical resection, RT
|
36
|
Nausea, vomiting, 10-kg weight loss within 1 month
|
CT, RT, immuno-therapy
|
Deceased for metastatic disease
|
Unknown
|
Kini et al. (2018) [35]
|
75
|
F
|
Unknown
|
Left gluteal region
|
Surgical resection, left pelvic and inguinal lymph nodes dissection
|
12
|
Recurrent vomiting and jaundice
|
CT
|
Deceased for metastatic disease
|
9 months
|
Durastante et al. (2021)
|
61
|
M
|
Caucasian
|
Unknown (right inguinal lymph nodes enlargement)
|
Right inguinal lymph nodes dissection, RT
|
9
|
Fatigue, anaemia and melena
|
Partial gastrectomy, immuno-therapy (anti-PDL1)
|
Receiving immuno-therapy (RT under evaluation)
|
NA
|