1. Sofroniew MV, Vinters HV (2010) Astrocytes: biology and pathology. Acta neuropathologica 119 (1):7-35
2. Pannasch U, Rouach N (2013) Emerging role for astroglial networks in information processing: from synapse to behavior. Trends in neurosciences 36 (7):405-417
3. Pekny M, Pekna M, Messing A, Steinhauser C, Lee JM, Parpura V, Hol EM, Sofroniew MV, Verkhratsky A (2016) Astrocytes: a central element in neurological diseases. Acta neuropathologica 131 (3):323-345
4. Sofroniew MV (2009) Molecular dissection of reactive astrogliosis and glial scar formation. Trends in neurosciences 32 (12):638-647
5. Farina C, Aloisi F, Meinl E (2007) Astrocytes are active players in cerebral innate immunity. Trends in immunology 28 (3):138-145
6. Kaul M, Garden GA, Lipton SA (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410 (6831):988-994. doi:10.1038/35073667
7. Zhou BY, Liu Y, Kim B, Xiao Y, He JJ (2004) Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes. Mol Cell Neurosci 27 (3):296-305. doi:10.1016/j.mcn.2004.07.003
8. Pandey HS, Seth P (2019) Friends Turn Foe-Astrocytes Contribute to Neuronal Damage in NeuroAIDS. J Mol Neurosci 69 (2):286-297. doi:10.1007/s12031-019-01357-1
9. Churchill MJ, Wesselingh SL, Cowley D, Pardo CA, McArthur JC, Brew BJ, Gorry PR (2009) Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia. Annals of neurology 66 (2):253-258
10. Gorry PR, Howard JL, Churchill MJ, Anderson JL, Cunningham A, Adrian D, McPhee DA, Purcell DF (1999) Diminished production of human immunodeficiency virus type 1 in astrocytes results from inefficient translation of gag, env, and nef mRNAs despite efficient expression of Tat and Rev. Journal of virology 73 (1):352-361
11. Carey AN, Sypek EI, Singh HD, Kaufman MJ, McLaughlin JP (2012) Expression of HIV-Tat protein is associated with learning and memory deficits in the mouse. Behavioural brain research 229 (1):48-56
12. Kim BO, Liu Y, Ruan Y, Xu ZC, Schantz L, He JJ (2003) Neuropathologies in transgenic mice expressing human immunodeficiency virus type 1 Tat protein under the regulation of the astrocyte-specific glial fibrillary acidic protein promoter and doxycycline. The American journal of pathology 162 (5):1693-1707
13. Bazargani N, Attwell D (2016) Astrocyte calcium signaling: the third wave. Nature neuroscience 19 (2):182-189
14. Parpura V, Basarsky TA, Liu F, Jeftinija K, Jeftinija S, Haydon PG (1994) Glutamate-mediated astrocyte-neuron signalling. Nature 369 (6483):744-747
15. Mothet JP, Parent AT, Wolosker H, Brady RO, Jr., Linden DJ, Ferris CD, Rogawski MA, Snyder SH (2000) D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proceedings of the National Academy of Sciences of the United States of America 97 (9):4926-4931
16. Coco S, Calegari F, Pravettoni E, Pozzi D, Taverna E, Rosa P, Matteoli M, Verderio C (2003) Storage and release of ATP from astrocytes in culture. The Journal of biological chemistry 278 (2):1354-1362
17. Fellin T, Pascual O, Gobbo S, Pozzan T, Haydon PG, Carmignoto G (2004) Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors. Neuron 43 (5):729-743
18. Haughey NJ, Holden CP, Nath A, Geiger JD (1999) Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat. Journal of neurochemistry 73 (4):1363-1374
19. Ferrari G, Langen H, Naito M, Pieters J (1999) A coat protein on phagosomes involved in the intracellular survival of mycobacteria. Cell 97 (4):435-447
20. Nal B, Carroll P, Mohr E, Verthuy C, Da Silva MI, Gayet O, Guo XJ, He HT, Alcover A, Ferrier P (2004) Coronin-1 expression in T lymphocytes: insights into protein function during T cell development and activation. International immunology 16 (2):231-240
21. Pieters J, Muller P, Jayachandran R (2013) On guard: coronin proteins in innate and adaptive immunity. Nature reviews 13 (7):510-518
22. Jayachandran R, Liu X, Bosedasgupta S, Muller P, Zhang CL, Moshous D, Studer V, Schneider J, Genoud C, Fossoud C, Gambino F, Khelfaoui M, Muller C, Bartholdi D, Rossez H, Stiess M, Houbaert X, Jaussi R, Frey D, Kammerer RA, Deupi X, de Villartay JP, Luthi A, Humeau Y, Pieters J (2014) Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signaling. PLoS biology 12 (3):e1001820
23. Mueller P, Massner J, Jayachandran R, Combaluzier B, Albrecht I, Gatfield J, Blum C, Ceredig R, Rodewald HR, Rolink AG, Pieters J (2008) Regulation of T cell survival through coronin-1-mediated generation of inositol-1,4,5-trisphosphate and calcium mobilization after T cell receptor triggering. Nature immunology 9 (4):424-431
24. Foger N, Rangell L, Danilenko DM, Chan AC (2006) Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis. Science (New York, NY 313 (5788):839-842
25. Jayachandran R, Sundaramurthy V, Combaluzier B, Mueller P, Korf H, Huygen K, Miyazaki T, Albrecht I, Massner J, Pieters J (2007) Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin. Cell 130 (1):37-50
26. Mugnier B, Nal B, Verthuy C, Boyer C, Lam D, Chasson L, Nieoullon V, Chazal G, Guo XJ, He HT, Rueff-Juy D, Alcover A, Ferrier P (2008) Coronin-1A links cytoskeleton dynamics to TCR alpha beta-induced cell signaling. PloS one 3 (10):e3467
27. Verkhratsky A, Orkand RK, Kettenmann H (1998) Glial calcium: homeostasis and signaling function. Physiol Rev 78 (1):99-141. doi:10.1152/physrev.1998.78.1.99
28. Kirischuk S, Moller T, Voitenko N, Kettenmann H, Verkhratsky A (1995) ATP-induced cytoplasmic calcium mobilization in Bergmann glial cells. J Neurosci 15 (12):7861-7871
29. Hamilton N, Vayro S, Kirchhoff F, Verkhratsky A, Robbins J, Gorecki DC, Butt AM (2008) Mechanisms of ATP- and glutamate-mediated calcium signaling in white matter astrocytes. Glia 56 (7):734-749. doi:10.1002/glia.20649
30. Tewari M, Monika, Varghse RK, Menon M, Seth P (2015) Astrocytes mediate HIV-1 Tat-induced neuronal damage via ligand-gated ion channel P2X7R. Journal of neurochemistry 132 (4):464-476
31. Verkhratsky A, Nedergaard M (2018) Physiology of Astroglia. Physiol Rev 98 (1):239-389. doi:10.1152/physrev.00042.2016
32. Dong Y, Benveniste EN (2001) Immune function of astrocytes. Glia 36 (2):180-190
33. Potter MC, Figuera-Losada M, Rojas C, Slusher BS (2013) Targeting the glutamatergic system for the treatment of HIV-associated neurocognitive disorders. J Neuroimmune Pharmacol 8 (3):594-607
34. John GR, Lee SC, Brosnan CF (2003) Cytokines: powerful regulators of glial cell activation. Neuroscientist 9 (1):10-22
35. Tatro ET, Scott ER, Nguyen TB, Salaria S, Banerjee S, Moore DJ, Masliah E, Achim CL, Everall IP (2010) Evidence for Alteration of Gene Regulatory Networks through MicroRNAs of the HIV-infected brain: novel analysis of retrospective cases. PloS one 5 (4):e10337. doi:10.1371/journal.pone.0010337
36. Fatima M, Prajapati B, Saleem K, Kumari R, Mohindar Singh Singal C, Seth P (2017) Novel insights into role of miR-320a-VDAC1 axis in astrocyte-mediated neuronal damage in neuroAIDS. Glia 65 (2):250-263. doi:10.1002/glia.23089
37. Sardo L, Vakil PR, Elbezanti W, El-Sayed A, Klase Z (2016) The inhibition of microRNAs by HIV-1 Tat suppresses beta catenin activity in astrocytes. Retrovirology 13:25. doi:10.1186/s12977-016-0256-y
38. Heaton RK, Clifford DB, Franklin DR, Jr., Woods SP, Ake C, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Rivera-Mindt M, Vigil OR, Taylor MJ, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Jernigan TL, Wong J, Grant I, Group C (2010) HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study. Neurology 75 (23):2087-2096. doi:10.1212/WNL.0b013e318200d727
39. Sacktor N, Robertson K (2014) Evolving clinical phenotypes in HIV-associated neurocognitive disorders. Curr Opin HIV AIDS 9 (6):517-520. doi:10.1097/COH.0000000000000102
40. Gannon P, Khan MZ, Kolson DL (2011) Current understanding of HIV-associated neurocognitive disorders pathogenesis. Curr Opin Neurol 24 (3):275-283. doi:10.1097/WCO.0b013e32834695fb
41. Suo D, Park J, Harrington AW, Zweifel LS, Mihalas S, Deppmann CD (2014) Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival. Nature neuroscience 17 (1):36-45. doi:10.1038/nn.3593
42. Woodman SE, Benveniste EN, Nath A, Berman JW (1999) Human immunodeficiency virus type 1 TAT protein induces adhesion molecule expression in astrocytes. J Neurovirol 5 (6):678-684. doi:10.3109/13550289909021296
43. Song HY, Ryu J, Ju SM, Park LJ, Lee JA, Choi SY, Park J (2007) Extracellular HIV-1 Tat enhances monocyte adhesion by up-regulation of ICAM-1 and VCAM-1 gene expression via ROS-dependent NF-kappaB activation in astrocytes. Exp Mol Med 39 (1):27-37. doi:10.1038/emm.2007.4
44. Liu X, Jana M, Dasgupta S, Koka S, He J, Wood C, Pahan K (2002) Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia. The Journal of biological chemistry 277 (42):39312-39319. doi:10.1074/jbc.M205107200
45. Flora G, Pu H, Hennig B, Toborek M (2006) Cyclooxygenase-2 is involved in HIV-1 Tat-induced inflammatory responses in the brain. Neuromolecular Med 8 (3):337-352. doi:10.1385/NMM:8:3:337