Aad, P.Y., Echternkamp, S.E., Sypherd, D.D., Schreiber, N.B. and Spicer, L.J., 2012. The hedgehog system in ovarian follicles of cattle selected for twin ovulations and births: evidence of a link between the IGF and hedgehog systems. Biol Reprod 87, 79.
Diamanti-Kandarakis, E., 2008. Polycystic ovarian syndrome: pathophysiology, molecular aspects and clinical implications. Expert Rev Mol Med 10, e3.
Franks, S., McCarthy, M.I. and Hardy, K., 2006. Development of polycystic ovary syndrome: involvement of genetic and environmental factors. Int J Androl 29, 278-85; discussion 286-90.
Galimberti, F., Busch, A.M., Chinyengetere, F., Ma, T., Sekula, D., Memoli, V.A., Dragnev, K.H., Liu, F., Johnson, K.C., Guo, Y., Freemantle, S.J., Andrew, A.S., Greninger, P., Robbins, D.J., Settleman, J., Benes, C. and Dmitrovsky, E., 2012. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations. Int J Oncol 41, 1751-61.
Gong, F., Li, X., Zhang, S., Ma, H., Cai, S., Li, J., Lin, G.E. and Lu, G., 2015. A modified ultra-long pituitary downregulation protocol improved endometrial receptivity and clinical outcome for infertile patients with polycystic ovarian syndrome. Exp Ther Med 10, 1865-1870.
Hammerschmidt, M., Brook, A. and McMahon, A.P., 1997. The world according to hedgehog. Trends Genet 13, 14-21.
Hirotsu, M., Setoguchi, T., Sasaki, H., Matsunoshita, Y., Gao, H., Nagao, H., Kunigou, O. and Komiya, S., 2010. Smoothened as a new therapeutic target for human osteosarcoma. Mol Cancer 9, 5.
Hooper, J.E. and Scott, M.P., 2005. Communicating with Hedgehogs. Nat Rev Mol Cell Biol 6, 306-17.
Ingham, P.W., Nakano, Y. and Seger, C., 2011. Mechanisms and functions of Hedgehog signalling across the metazoa. Nat Rev Genet 12, 393-406.
Ingham, P.W., Taylor, A.M. and Nakano, Y., 1991. Role of the Drosophila patched gene in positional signalling. Nature 353, 184-7.
Japur, C.C., Diez-Garcia, R.W., de Oliveira Penaforte, F.R. and de Sa, M.F., 2014. Imbalance Between Postprandial Ghrelin and Insulin Responses to an Ad Libitum Meal in Obese Women With Polycystic Ovary Syndrome. Reprod Sci 21, 1020-1026.
Jiang, S.W., Xu, S., Chen, H., Liu, X., Tang, Z., Cui, Y. and Liu, J., 2017. Pathologic significance of SET/I2PP2A-mediated PP2A and non-PP2A pathways in polycystic ovary syndrome (PCOS). Clin Chim Acta 464, 155-159.
King, P.J., Guasti, L. and Laufer, E., 2008. Hedgehog signalling in endocrine development and disease. J Endocrinol 198, 439-50.
Lee, R.T., Zhao, Z. and Ingham, P.W., 2016. Hedgehog signalling. Development 143, 367-72.
Li, T., Mo, H., Chen, W., Li, L., Xiao, Y., Zhang, J., Li, X. and Lu, Y., 2017. Role of the PI3K-Akt Signaling Pathway in the Pathogenesis of Polycystic Ovary Syndrome. Reprod Sci 24, 646-655.
Lubik, A.A., Nouri, M., Truong, S., Ghaffari, M., Adomat, H.H., Corey, E., Cox, M.E., Li, N., Guns, E.S., Yenki, P., Pham, S. and Buttyan, R., 2017. Paracrine sonic hedgehog signaling contributes significantly to acquired steroidogenesis in the prostate tumor microenvironment. Int J Cancer 140, 358-369.
Migone, F.F., Ren, Y., Cowan, R.G., Harman, R.M., Nikitin, A.Y. and Quirk, S.M., 2012. Dominant activation of the hedgehog signaling pathway alters development of the female reproductive tract. Genesis 50, 28-40.
Nasri, K., Hantoushzadeh, S., Aghadavod, E., Taghizadeh, M. and Asemi, Z., 2017. The Effects of Omega-3 Fatty Acids Supplementation on Gene Expression Involved in the Insulin and Lipid Signaling Pathway in Patients with Polycystic Ovary Syndrome. Horm Metab Res 49, 446-451.
Nilsson, E. and Skinner, M.K., 2001. Cellular interactions that control primordial follicle development and folliculogenesis. J Soc Gynecol Investig 8, S17-20.
Norman, R.J., Dewailly, D., Legro, R.S. and Hickey, T.E., 2007. Polycystic ovary syndrome. Lancet 370, 685-97.
Nusslein-Volhard, C. and Wieschaus, E., 1980. Mutations affecting segment number and polarity in Drosophila. Nature 287, 795-801.
Parrott, J.A. and Skinner, M.K., 1998. Thecal cell-granulosa cell interactions involve a positive feedback loop among keratinocyte growth factor, hepatocyte growth factor, and Kit ligand during ovarian follicular development. Endocrinology 139, 2240-5.
Ren, J., Sha, A., Han, D., Li, P., Geng, J. and Ma, C., 2014. Does prolonged pituitary down-regulation with gonadotropin-releasing hormone agonist improve the live-birth rate in in vitro fertilization treatment? Fertil Steril 102, 75-81.
Ren, Y., Cowan, R.G., Harman, R.M. and Quirk, S.M., 2009. Dominant activation of the hedgehog signaling pathway in the ovary alters theca development and prevents ovulation. Mol Endocrinol 23, 711-23.
Ren, Y., Cowan, R.G., Migone, F.F. and Quirk, S.M., 2012. Overactivation of hedgehog signaling alters development of the ovarian vasculature in mice. Biol Reprod 86, 174.
Rennert, C., Eplinius, F., Hofmann, U., Johanning, J., Rolfs, F., Schmidt-Heck, W., Guthke, R., Gebhardt, R., Ricken, A.M. and Matz-Soja, M., 2017. Conditional loss of hepatocellular Hedgehog signaling in female mice leads to the persistence of hepatic steroidogenesis, androgenization and infertility. Arch Toxicol 91, 3677-3687.
Rotterdam, E.A.-S.P.C.W.G., 2004. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril 81, 19-25.
Russell, M.C., Cowan, R.G., Harman, R.M., Walker, A.L. and Quirk, S.M., 2007. The hedgehog signaling pathway in the mouse ovary. Biol Reprod 77, 226-36.
Setji, T.L. and Brown, A.J., 2014. Polycystic ovary syndrome: update on diagnosis and treatment. Am J Med 127, 912-9.
Spicer, L.J., Sudo, S., Aad, P.Y., Wang, L.S., Chun, S.Y., Ben-Shlomo, I., Klein, C. and Hsueh, A.J., 2009. The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells. Reproduction 138, 329-39.
Tan, J., Wen, X.Y., Su, Q., Huang, Z.H., He, J.X., Xin, C.L., Wu, Q.F. and Zou, Y., 2016. Reduced expression of SCF in serum and follicle from patients with polycystic ovary syndrome. Eur Rev Med Pharmacol Sci 20, 5049-5057.
Tandulwadkar, S.R., Lodha, P.A. and Mangeshikar, N.T., 2014. Obstetric complications in women with IVF conceived pregnancies and polycystic ovarian syndrome. J Hum Reprod Sci 7, 13-8.
Wijgerde, M., Ooms, M., Hoogerbrugge, J.W. and Grootegoed, J.A., 2005. Hedgehog signaling in mouse ovary: Indian hedgehog and desert hedgehog from granulosa cells induce target gene expression in developing theca cells. Endocrinology 146, 3558-66.
Wu, X.Q., Wang, Y.Q., Xu, S.M., Liu, J.F., Bi, X.Y., Wang, Z.Q. and Zhang, J.P., 2017. The WNT/beta-catenin signaling pathway may be involved in granulosa cell apoptosis from patients with PCOS in North China. J Gynecol Obstet Hum Reprod 46, 93-99.
Xing, Y., Liu, Y.X., Liu, X., Wang, S.L., Li, P., Lin, X.H., Sui, C.L., Xu, C., Qi, B. and Tong, Q., 2017. Effects of Gui Zhu Yi Kun formula on the P53/AMPK pathway of autophagy in granulosa cells of rats with polycystic ovary syndrome. Exp Ther Med 13, 3567-3573.
Zhang, C.L., Wang, H., Yan, C.Y., Gao, X.F. and Ling, X.J., 2017. Deregulation of RUNX2 by miR-320a deficiency impairs steroidogenesis in cumulus granulosa cells from polycystic ovary syndrome (PCOS) patients. Biochem Biophys Res Commun 482, 1469-1476.