The emergence of the COVID-19 outbreak caused by SARS-nCoV2 led to mass-scale mortalities worldwide. The need of the hour is to develop strategies and design drugs/vaccines to control this contagion. Current research predicted the promising drug agents from the Carica papaya compounds by docking and MD simulations approaches with two major drug target proteins of spike receptor-binding domain and RNA-dependent RNA polymerase of SARS-nCoV2. MOE & PyRx softwares were used for ligand-protein interactions and docking scores predictions. Additionally, MD simulation analysis was performed on the ligands with the lowest binding energies using the NAMD/VMD softwares to compute the stability of the best complexes. Furthermore, SwissADME analysis was also performed to check Lipinski's physiochemical parameters of ligands. Our docking results showed the best binding energies of Lutein & β-cryptoxanthin ligands with both of the proteins followed by MDS analysis to check the complex stability and physical perturbations to determine the fitness of these complexes as a potential drug agent against COVID-19 infection. The findings of the current study need experimental validations to proceed further for clinical trials.