1 Alam, M. N. & Huq, F. Comprehensive review on tumour active palladium compounds and structure–activity relationships. Coordination Chemistry Reviews 316, 36-67 (2016).
2 Alam, M. N. et al. Crystal Structure, Antitumour and Antibacterial Activity of Imidazo [1, 2‐α] pyridine Ligand Containing Palladium Complexes. ChemistrySelect 5, 668-673 (2020).
3 Prachayasittikul, V., Prachayasittikul, S., Ruchirawat, S. & Prachayasittikul, V. 8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications. Drug design, development and therapy 7, 1157 (2013).
4 Qin, Q.-P. et al. Studies on antitumor mechanism of two planar platinum (II) complexes with 8-hydroxyquinoline: synthesis, characterization, cytotoxicity, cell cycle and apoptosis. European journal of medicinal chemistry 92, 302-313 (2015).
5 Oliveri, V. & Vecchio, G. 8-Hydroxyquinolines in medicinal chemistry: A structural perspective. European journal of medicinal chemistry 120, 252-274 (2016).
6 Arzuman, L., Beale, P., Yu, J. Q., Proschogo, N. & Huq, F. Synthesis of a monofunctional platinum compound and its activity alone and in combination with phytochemicals in ovarian tumor models. Anticancer research 34, 7077-7090 (2014).
7 Alam, M. N., Yu, J. Q., Beale, P. & Huq, F. Cisplatin in combination with emetine and patulin showed dose and sequence dependent synergism against ovarian cancer. Synergy 10, 100060 (2020).
8 Alam, N., Yu, J., Beale, P. & Huq, F. Dose and Sequence Dependent Synergism from the Combination of Oxaliplatin with Emetine and Patulin against Colorectal Cancer. Anti-cancer agents in medicinal chemistry (2019).
9 Prout, C. & Wheeler, A. Molecular complexes. Part VI. The crystal and molecular structure of 8-hydroxyquinolinatopalladium (II). Journal of the Chemical Society A: Inorganic, Physical, Theoretical, 1286-1290 (1966).
10 Low, K. H. et al. Bis (5, 7‐dimethyl‐8‐hydroxyquinolinato) platinum (II) Complex for Efficient Organic Heterojunction Solar Cells. Chemistry–An Asian Journal 6, 3223-3229 (2011).
11 Tardito, S. et al. Copper-dependent cytotoxicity of 8-hydroxyquinoline derivatives correlates with their hydrophobicity and does not require caspase activation. Journal of medicinal chemistry 55, 10448-10459 (2012).
12 Jiang, H. et al. Nitroxoline (8-hydroxy-5-nitroquinoline) is more a potent anti-cancer agent than clioquinol (5-chloro-7-iodo-8-quinoline). Cancer letters 312, 11-17 (2011).
13 Ding, W.-Q., Liu, B., Vaught, J. L., Yamauchi, H. & Lind, S. E. Anticancer activity of the antibiotic clioquinol. Cancer research 65, 3389-3395 (2005).
14 SHEN, A. Y., WU, S. N. & CHIU, C. T. Synthesis and Cytotoxicity Evaluation of Some 8‐Hydroxyquinoline Derivatives. Journal of pharmacy and pharmacology 51, 543-548 (1999).
15 Vranec, P. et al. Low-dimensional compounds containing bioactive ligands. V: Synthesis and characterization of novel anticancer Pd(II) ionic compounds with quinolin-8-ol halogen derivatives. J Inorg Biochem 131, 37-46, doi:10.1016/j.jinorgbio.2013.10.018 (2014).
16 Szklarczyk, D. et al. The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible. Nucleic acids research, gkw937 (2016).
17 Xia, J., Gill, E. E. & Hancock, R. E. NetworkAnalyst for statistical, visual and network-based meta-analysis of gene expression data. Nature protocols 10, 823-844 (2015).
18 Kuleshov, M. V. et al. Enrichr: a comprehensive gene set enrichment analysis web server 2016 update. Nucleic acids research 44, W90-W97 (2016).
19 Consortium, G. O. The gene ontology resource: 20 years and still GOing strong. Nucleic acids research 47, D330-D338 (2019).
20 Zhu, Y., Qiu, P. & Ji, Y. TCGA-assembler: open-source software for retrieving and processing TCGA data. Nature methods 11, 599-600 (2014).
21 Piñero, J. et al. DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes. Database 2015 (2015).
22 Valenzuela, H. F., Grabauskas, T., Chen, M., Ruiz, T. & Kwak, Y. (Am Assoc Immnol, 2017).
23 Chen, P., Li, J., Jiang, H.-G., Lan, T. & Chen, Y.-C. Curcumin reverses cisplatin resistance in cisplatin-resistant lung caner cells by inhibiting FA/BRCA pathway. Tumor Biology 36, 3591-3599, doi:10.1007/s13277-014-2996-4 (2015).
24 Baharuddin, P. et al. Curcumin improves the efficacy of cisplatin by targeting cancer stem-like cells through p21 and cyclin D1-mediated tumour cell inhibition in non-small cell lung cancer cell lines. Oncology reports 35, 13-25 (2016).
25 Park, B. H. et al. Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2. Oncotarget 7, 63870-63886, doi:10.18632/oncotarget.11563 (2016).
26 Nessa, M. U., Beale, P., Chan, C., Yu, J. Q. & Huq, F. Studies on combination of platinum drugs cisplatin and oxaliplatin with phytochemicals anethole and curcumin in ovarian tumour models. Anticancer Res 32, 4843-4850 (2012).
27 Tunc, D. et al. Cytotoxic and apoptotic effects of the combination of palladium (II) 5,5-diethylbarbiturate complex with bis(2-pyridylmethyl)amine and curcumin on non small lung cancer cell lines. Bioorganic & Medicinal Chemistry 25, 1717-1723, doi:https://doi.org/10.1016/j.bmc.2017.01.043 (2017).
28 Kuo, C.-L. et al. Apoptotic death in curcumin-treated NPC-TW 076 human nasopharyngeal carcinoma cells is mediated through the ROS, mitochondrial depolarization and caspase-3-dependent signaling responses. International journal of oncology 39, 319-328 (2011).
29 Hatcher, H., Planalp, R., Cho, J., Torti, F. & Torti, S. Curcumin: from ancient medicine to current clinical trials. Cellular and Molecular Life Sciences 65, 1631-1652 (2008).
30 Banerjee, A., Kunwar, A., Mishra, B. & Priyadarsini, K. Concentration dependent antioxidant/pro-oxidant activity of curcumin: Studies from AAPH induced hemolysis of RBCs. Chemico-biological interactions 174, 134-139 (2008).
31 Gan, R.-Y., Li, H.-B., Sui, Z.-Q. & Corke, H. Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review. Critical reviews in food science and nutrition, 1-18 (2017).
32 Mayr, C. et al. The green tea catechin epigallocatechin gallate induces cell cycle arrest and shows potential synergism with cisplatin in biliary tract cancer cells. BMC complementary and alternative medicine 15, 194 (2015).
33 Bimonte, S. et al. Inhibitory effect of (-)-epigallocatechin-3-gallate and bleomycin on human pancreatic cancer MiaPaca-2 cell growth. Infectious agents and cancer 10, 22-22 (2015).
34 Luo, T. et al. (-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma. Breast Cancer Research 12, R8 (2010).
35 Mazumder, M. E. H., Beale, P., Chan, C., Yu, J. Q. & Huq, F. Epigallocatechin gallate acts synergistically in combination with cisplatin and designed trans-palladiums in ovarian cancer cells. Anticancer research 32, 4851-4860 (2012).
36 Min, K.-j. & Kwon, T. K. Anticancer effects and molecular mechanisms of epigallocatechin-3-gallate. Integrative Medicine Research 3, 16-24 (2014).
37 Alam, M. N., Almoyad, M. & Huq, F. Polyphenols in colorectal cancer: current state of knowledge including clinical trials and molecular mechanism of action. BioMed research international 2018 (2018).
38 Hermersdörfer, H. RI Freshney: Culture of Animal Cells. A Manual of Basic Technique. 486 Seiten, zahlr. Abb. und Tab. Wiley‐Liss, a John Wiley and Sons, Inc., Publication. New York, Chichester, Brisbane, Toronto. Singapore 1994. Preis: 69.95 US$. Food/Nahrung 39, 184-185 (1995).
39 Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of immunological methods 65, 55-63 (1983).