General demographic characteristics
A total of 8040 HCWs participated in the survey, of them 3844 (47.8%) were nurses, 2836 (35.3%) were doctors and 1360 (16.9%) were technicians. Of the respondents, most were less than 50 years old (90.4%) and female (80.4%), 70.3% stated they had participated in the prevention and control of COVID-19 epidemic, 34.4% admitted coming from departments may directly involve in the diagnosis and treatment of patients, and 35.1% reported having received other vaccines in the past 3 years. Details are summarized in table 1.
Perception to COVID-19 epidemic
The vast majority (95.8%) of the respondents considered that consequences of suffering from SARS-CoV-2 infection were “serious”. 80.1% perceived they might be infected with the virus. 57.5% admitted they were at greater risk of SARS-CoV-2 infection than others, the proportion of doctors, nurses and technicians holding the view decreased successively (P<0.001). Nearly half of the respondents were unsure whether the outbreak in China would come back, and thought the global COVID-19 epidemic would last for a long time (59.2% of doctors hold this view, significantly higher than nurses and technicians (P<0.001)). 67.6% of the respondents agreed that COVID-19 epidemic can be prevented by vaccination, and a slightly lower proportion believed in the safety and effectiveness of the future vaccine. 73.0% of the respondents reported that their life had been seriously disturbed by the epidemic in the past three months, and 43.6% estimated their life and work would still be disturbed in the next six months. Table 2 shows the differences of perception in doctors, nurses and technicians when answered the same question.
Attitudes to COVID-19 vaccine
Compared with the official media’s propaganda (80.4%), HCWs investigated believed more in the professional staff' advice (94.1%). 80.0% were convinced of COVID-19 vaccine approved for license have been fully evaluated in clinical trials, and 77.4% wanted the future vaccine free of charge. Most importantly, 67.1% of HCWs surveyed reported that they would get COVID-19 vaccination, 7.9% said they would not, and 25.0% said they were unsure. The proportion of those would advise family members to get vaccination (68.2%) was similar to that of their own willingness to vaccinate, however, the proportion of willingness to take children to get vaccination was significantly decreased to 61.9%. For the respondents would be vaccinated, vaccination campaign organized by hospital (75.3%) was obviously more acceptable than vaccination offered by community clinic (24.7%). In general, even if there were statistical differences in the answers of doctors, nurses and technicians on some questions for attitudes to COVID-19 vaccine, the proportion was very similar (table3).
Univariate associations between intention to accept COVID-19 vaccination and the related variables are shown in table 4. gender (P=0.011), age (P<0.001), occupation categories (P<0.001), ward type (P<0.001), highest academic degree (P<0.001), professional ranks and titles (P<0.001), underlying disease (P<0.001), participated in the prevention and control of COVID-19 epidemic (P=0.019), received other vaccines in the past 3 years (P<0.001) and received seasonal influenza vaccine (P<0.001) were significantly associated with greater intention to accept vaccination.
Multiple logistic regression model
In multiple logistic regression models, some factors showed positive significantly association with intention to get vaccination (table 5), which included “level II hospital” (OR:1.303, P=0.001), “level III” hospital (OR:1.237, P=0.004), “Agreed with suffering from SARS-CoV-2 infection is Serious” (OR:1.368, P=0.031), “Agreed with China's COVID-19 epidemic will come back” (OR:1.346, P<0.001), “Agreed with the global COVID-19 epidemic will last for a long time” (OR:1.208, P=0.004), “Agreed with COVID-19 can be prevented by vaccination” (OR:1.747, P<0.001), “Agreed with the COVID-19 vaccine is safe” (OR:1.915, P<0.001), “Agreed with the COVID-19 vaccine is effective” (OR:1.409, P<0.001), and “Trusted the propaganda of the official media” (OR:1.268, P=0.002). Two factors showed stronger positive significantly association, which were “Wanted the COVID-19 vaccine free of charge” (OR:5.807, P<0.001) and “believed COVID-19 vaccine approved for license have been fully evaluated in clinical trials” (OR:4.485, P<0.001). Two other factors showed negative significantly association, which were “highest academic degree” (OR:0.840, P<0.001) and “professional ranks and titles” (OR:0.930, P=0.049).