[1] Stensvold CR, Clark CG. Pre-empting Pandora’s Box: Blastocystis Subtypes Revisited. Trends Parasitol 2020;36:229–32. https://doi.org/10.1016/j.pt.2019.12.009.
[2] Wong KHS, Ng GC, Lin RTP, Yoshikawa H, Taylor MB, Tan KSW. Predominance of subtype 3 among Blastocystis isolates from a major hospital in Singapore. Parasitol Res 2008;102:663–70. https://doi.org/10.1007/s00436-007-0808-0.
[3] Tan KSW. New Insights on Classification, Identification, and Clinical Relevance of Blastocystis spp. Clin Microbiol Rev 2008;21:639–65. https://doi.org/10.1128/CMR.00022-08.
[4] Batista L, Pérez Jove J, Rosinach M, Gonzalo V, Sainz E, Loras C, et al. Low efficacy of metronidazole in the eradication of Blastocystis hominis in symptomatic patients: Case series and systematic literature review. Gastroenterol Hepatol 2017;40:381–7. https://doi.org/10.1016/j.gastrohep.2016.11.003.
[5] El Safadi D, Cian A, Nourrisson C, Pereira B, Morelle C, Bastien P, et al. Prevalence, risk factors for infection and subtype distribution of the intestinal parasite Blastocystis sp. from a large-scale multi-center study in France. BMC Infect Dis 2016;16:451. https://doi.org/10.1186/s12879-016-1776-8.
[6] Reh L, Muadica AS, Köster PC, Balasegaram S, Verlander NQ, Chércoles ER, et al. Substantial prevalence of enteroparasites Cryptosporidium spp., Giardia duodenalis and Blastocystis sp. in asymptomatic schoolchildren in Madrid, Spain, November 2017 to June 2018. Eurosurveillance 2019;24:1900241. https://doi.org/10.2807/1560-7917.ES.2019.24.43.1900241.
[7] Scanlan PD, Stensvold CR, Rajilić-Stojanović M, Heilig HGHJ, De Vos WM, O’Toole PW, et al. The microbial eukaryote Blastocystis is a prevalent and diverse member of the healthy human gut microbiota. FEMS Microbiol Ecol 2014;90:326–30. https://doi.org/10.1111/1574-6941.12396.
[8] Zierdt CH. Pathogenicity of Blastocystis hominis. J Clin Microbiol 1991;29:662–3.
[9] Shlim DR, Hoge CW, Rajah R, Rabold JG, Echeverria P. Is Blastocystis hominis a cause of diarrhea in travelers? A prospective controlled study in Nepal. Clin Infect Dis Off Publ Infect Dis Soc Am 1995;21:97–101.
[10] Miller RA, Minshew BH. Blastocystis hominis: an organism in search of a disease. Rev Infect Dis 1988;10:930–8.
[11] Senay H, MacPherson D. Blastocystis hominis: epidemiology and natural history. J Infect Dis 1990;162:987–90. https://doi.org/10.1093/infdis/162.4.987.
[12] Kain KC, Noble MA, Freeman HJ, Barteluk RL. Epidemiology and clinical features associated with Blastocystis hominis infection. Diagn Microbiol Infect Dis 1987;8:235–44.
[13] Kuo H-Y, Chiang D-H, Wang C-C, Chen T-L, Fung C-P, Lin C-P, et al. Clinical significance of Blastocystis hominis: experience from a medical center in northern Taiwan. J Microbiol Immunol Infect Wei Mian Yu Gan Ran Za Zhi 2008;41:222–6.
[14] Heyland K, Friedt M, Buehr P, Braegger CP. No advantage for antibiotic treatment over placebo in Blastocystis hominis-positive children with recurrent abdominal pain. J Pediatr Gastroenterol Nutr 2012;54:677–9. https://doi.org/10.1097/MPG.0b013e31823a29a7.
[15] Rajamanikam A, Hooi HS, Kudva M, Samudi C, Kumar S. Resistance towards metronidazole in Blastocystis sp.: A pathogenic consequence. PLoS ONE 2019;14. https://doi.org/10.1371/journal.pone.0212542.
[16] Zaman V, Zaki M. Resistance of Blastocystis hominis cysts to metronidazole. Trop Med Int Health TM IH 1996;1:677–8.
[17] Wu Z, Mirza H, Tan KSW. Intra-Subtype Variation in Enteroadhesion Accounts for Differences in Epithelial Barrier Disruption and Is Associated with Metronidazole Resistance in Blastocystis Subtype-7. PLoS Negl Trop Dis 2014;8. https://doi.org/10.1371/journal.pntd.0002885.
[18] Taylor DN, Houston R, Shlim DR, Bhaibulaya M, Ungar BL, Echeverria P. Etiology of diarrhea among travelers and foreign residents in Nepal. JAMA 1988;260:1245–8.
[19] Sheehan DJ, Raucher BG, McKitrick JC. Association of Blastocystis hominis with signs and symptoms of human disease. J Clin Microbiol 1986;24:548–50.
[20] Qadri SM, al-Okaili GA, al-Dayel F. Clinical significance of Blastocystis hominis. J Clin Microbiol 1989;27:2407–9.
[21] Doyle PW, Helgason MM, Mathias RG, Proctor EM. Epidemiology and pathogenicity of Blastocystis hominis. J Clin Microbiol 1990;28:116–21.
[22] Rossignol J-F, Kabil SM, Said M, Samir H, Younis AM. Effect of nitazoxanide in persistent diarrhea and enteritis associated with Blastocystis hominis. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc 2005;3:987–91.
[23] Dinleyici EC, Eren M, Dogan N, Reyhanioglu S, Yargic ZA, Vandenplas Y. Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection. Parasitol Res 2011;108:541–5. https://doi.org/10.1007/s00436-010-2095-4.
[24] Nigro L, Larocca L, Massarelli L, Patamia I, Minniti S, Palermo F, et al. A Placebo-Controlled Treatment Trial of Blastocystis hominis Infection with Metronidazole. J Travel Med 2003;10:128–130.
[25] Scicluna SM, Tawari B, Clark CG. DNA Barcoding of Blastocystis. Protist 2006;157:77–85. https://doi.org/10.1016/j.protis.2005.12.001.
[26] Markell EK, Udkow MP. Blastocystis hominis: pathogen or fellow traveler? Am J Trop Med Hyg 1986;35:1023–6. https://doi.org/10.4269/ajtmh.1986.35.1023.
[27] Alfellani MA, Stensvold CR, Vidal-Lapiedra A, Onuoha ESU, Fagbenro-Beyioku AF, Clark CG. Variable geographic distribution of Blastocystis subtypes and its potential implications. Acta Trop 2013;126:11–8. https://doi.org/10.1016/j.actatropica.2012.12.011.
[28] Stensvold CR, Ahmed UN, Andersen LO, Nielsen HV. Development and Evaluation of a Genus-Specific, Probe-Based, Internal-Process-Controlled Real-Time PCR Assay for Sensitive and Specific Detection of Blastocystis spp. J Clin Microbiol 2012;50:1847–51. https://doi.org/10.1128/JCM.00007-12.
[29] Domínguez-Márquez MV, Guna R, Muñoz C, Gómez-Muñoz MT, Borrás R. High prevalence of subtype 4 among isolates of Blastocystis hominis from symptomatic patients of a health district of Valencia (Spain). Parasitol Res 2009;105:949–55. https://doi.org/10.1007/s00436-009-1485-y.
[30] Stensvold CR, Christiansen DB, Olsen KEP, Nielsen HV. Blastocystis sp. subtype 4 is common in Danish Blastocystis-positive patients presenting with acute diarrhea. Am J Trop Med Hyg 2011;84:883–5. https://doi.org/10.4269/ajtmh.2011.11-0005.
[31] Mattiucci S, Crisafi B, Gabrielli S, Paoletti M, Cancrini G. Molecular epidemiology and genetic diversity of Blastocystis infection in humans in Italy. Epidemiol Infect 2016;144:635–46. https://doi.org/10.1017/S0950268815001697.