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Research article
Unilateral Versus Bilateral Pedicle Screw Fixation With Oblique Lateral Interbody Fusion in the Treatment of Multi-level Degenerative Lumbar Disease: a Prospective Study
Zhaohui Ge
Ningxia Medical University
Corresponding Author
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Background: The purpose of this study was to compare the clinical and radiological outcomes of oblique lateral interbody fusion (OLIF) combined with unilateral (UPSF) and bilateral pedicle screw fixation (BPSF) in the treatment of multi-level degenerative lumbar disease (LDD).
Methods: We conducted a prospective study from May 2016 to June 2018. A total of 81 LDD patients were randomized into groups. The first group involving 39 patients received OLIF combined with USPF (UPS group), and the second group of 41 patients received OLIF combined with BPSF (BPS group). The perioperative conditions included intraoperative bleeding, operating time, average hospital stay, and hospitalization expenses. The clinical outcomes included Visual Analogue Scale (VAS), Oswestry Disability Index (ODI), and complications. Moreover, the radiological outcomes included disc height, fusion rate, and cage subsidence rate. These perioperative conditions, clinical outcomes, and radiological conditions of the two study groups were evaluated and compared. All the patients were followed up for 24 to 28 months, with an average follow-up time of 26 months.
Results: The intraoperative bleeding, operating time, and hospitalization expenses of the UPS group were significantly less compared with those of the BPS group. Compared with preoperatively, the VAS and ODI scores of the two groups were improved significantly after the operation. At 6 months after operation, the VAS score for back pain and ODI of the UPS group were better than in the BPS group (P < 0.05). Both groups were able to maintain the intervertebral space height of the fusion segment, and there was no significant difference in the fusion rate at the 24 months. There were no significant differences in complications. At the 24 months, there was no significant difference in the cage subsidence of the fusion segment between the two groups. Finally, there was no loose screw and screw fracture in both groups.
Conclusions: OLIF combined with UPSF is an effective and reliable surgical method for the treatment of multilevel LDD.
Keywords
Unilateral pedicle screw, multi-level degenerative lumbar disease, oblique lumbar interbody fusion
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Research article
Unilateral Versus Bilateral Pedicle Screw Fixation With Oblique Lateral Interbody Fusion in the Treatment of Multi-level Degenerative Lumbar Disease: a Prospective Study
Zhaohui Ge
Ningxia Medical University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 18 Dec, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedic Surgery
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The purpose of this study was to compare the clinical and radiological outcomes of oblique lateral interbody fusion (OLIF) combined with unilateral (UPSF) and bilateral pedicle screw fixation (BPSF) in the treatment of multi-level degenerative lumbar disease (LDD).
Methods: We conducted a prospective study from May 2016 to June 2018. A total of 81 LDD patients were randomized into groups. The first group involving 39 patients received OLIF combined with USPF (UPS group), and the second group of 41 patients received OLIF combined with BPSF (BPS group). The perioperative conditions included intraoperative bleeding, operating time, average hospital stay, and hospitalization expenses. The clinical outcomes included Visual Analogue Scale (VAS), Oswestry Disability Index (ODI), and complications. Moreover, the radiological outcomes included disc height, fusion rate, and cage subsidence rate. These perioperative conditions, clinical outcomes, and radiological conditions of the two study groups were evaluated and compared. All the patients were followed up for 24 to 28 months, with an average follow-up time of 26 months.
Results: The intraoperative bleeding, operating time, and hospitalization expenses of the UPS group were significantly less compared with those of the BPS group. Compared with preoperatively, the VAS and ODI scores of the two groups were improved significantly after the operation. At 6 months after operation, the VAS score for back pain and ODI of the UPS group were better than in the BPS group (P < 0.05). Both groups were able to maintain the intervertebral space height of the fusion segment, and there was no significant difference in the fusion rate at the 24 months. There were no significant differences in complications. At the 24 months, there was no significant difference in the cage subsidence of the fusion segment between the two groups. Finally, there was no loose screw and screw fracture in both groups.
Conclusions: OLIF combined with UPSF is an effective and reliable surgical method for the treatment of multilevel LDD.
Figure 1
Figure 2