1 Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020; 70(1): 7-30.
2 Miller KD, Nogueira L, Mariotto AB, Rowland JH, Yabroff KR, Alfano CM et al. Cancer treatment and survivorship statistics, 2019. CA Cancer J Clin. 2019; 69(5): 363-85.
3 Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018; 68(6): 394-424.
4 Ni Q, Zhang F, Zhang Y, Zhu G, Wang Z, Teng Z et al. In Situ shRNA synthesis on DNA-polylactide nanoparticles to treat multidrug resistant breast cancer. Adv Mater. 2018; 30 (10). doi: 10.1002/adma.201705737.
5 Sun W, Zhao X, Wang Z, Chu Y, Mao L, Lin S et al. Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway. Mol Metab. 2019; 28:48-57.
6 Majumder S, Taylor WR, Yab TC, Berger CK, Dukek BA, Cao X et al. Novel methylated DNA markers discriminate advanced neoplasia in pancreatic cysts: marker discovery, tissue validation, and cyst fluid testing. Am J Gastroenterol. 2019; 114(9): 1539-49.
7 Majumder S, Raimondo M, Taylor WR, Yab TC, Berger CK, Dukek BA et al. Methylated DNA in pancreatic juice distinguishes patients with pancreatic cancer from controls. Clin Gastroenterol Hepatol. 2020; 18(3): 676-83.
8 Zheng Y, Huang Q, Ding Z, Liu T, Xue C, Sang X et al. Genome-wide DNA methylation analysis identifies candidate epigenetic markers and drivers of hepatocellular carcinoma. Brief Bioinform. 2018; 19(1): 101-8.
9 Liu CT, Monda KL, Taylor KC, Lange L, Demerath EW, Palmas W et al. Genome-wide association of body fat distribution in African ancestry populations suggests new loci. PLoS genet. 2013; 9(8): e1003681.
10 Hu Z, Shi Y, Mo X, Xu J, Zhao B, Lin Y et al. A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations. Nat Genet. 2013; 45(7): 818-21.
11 Gozzi G, Chelbi ST, Manni P, Alberti L, Fonda S, Saponaro S et al. Promoter methylation and downregulated expression of the TBX15 gene in ovarian carcinoma. Oncol lett. 2016; 12(4): 2811-9.
12 Xu Q, Liu LZ, Yin Y, He J, Li Q, Qian X et al. Regulatory circuit of PKM2/NF-kappaB/miR-148a/152-modulated tumor angiogenesis and cancer progression. Oncogene. 2015; 34(43): 5482-93.
13 Wang W, Cantos-Fernandes S, Lv Y, Kuerban H, Ahmad S, Wang C et al. Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin. Nat Commun. 2017; 8(1): 70.
14 Dai X, Hua T, Hong T. Integrated diagnostic network construction reveals a 4-gene panel and 5 cancer hallmarks driving breast cancer heterogeneity. Sci Rep. 2017; 7(1): 6827.
15 Ganguly A, Yang H, Cabral F. Overexpression of mitotic centromere-associated Kinesin stimulates microtubule detachment and confers resistance to paclitaxel. Mol Cancer Ther. 2011; 10(6): 929-37.
16 Manning CS, Hooper S, Sahai EA. Intravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cells. Oncogene. 2014; 34(33): 4320-32.
17 Zaganjor E, Weil LM, Gonzales JX, Minna JD, Cobb MH. Ras transformation uncouples the kinesin-coordinated cellular nutrient response. Proc Natl Acad Sci U S A. 2014; 111(29): 10568-73.
18 Macintyre AN, Rathmell JC. PKM2 and the tricky balance of growth and energy in cancer. Mol Cell. 2011; 42(6): 713-4.
19 Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G et al. PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells. Cell. 2013; 155(2): 397-409.
20 Zhou Z, Li M, Zhang L, Zhao H, Sahin O, Chen J et al. Oncogenic kinase-induced PKM2 tyrosine 105 phosphorylation converts nononcogenic pkm2 to a tumor promoter and induces cancer stem-like cells. Cancer Res. 2018; 78(9): 2248-61.
21 Liu F, Ma F, Wang Y, Hao L, Zeng H, Jia C et al. PKM2 methylation by CARM1 activates aerobic glycolysis to promote tumorigenesis. Nat Cell Biol. 2017; 19(11): 1358-70.
22 Tamada M, Nagano O, Tateyama S, Ohmura M, Yae T, Ishimoto T et al. Modulation of glucose metabolism by CD44 contributes to antioxidant status and drug resistance in cancer cells. Cancer Res. 2012; 72(6): 1438-48.
23 Pan C, Wang X, Shi K, Zheng Y, Li J, Chen Y et al. MiR-122 reverses the doxorubicin-resistance in hepatocellular carcinoma cells through regulating the tumor metabolism. PloS one. 2016; 11(5): e0152090.
24 He J, Yu JJ, Xu Q, Wang L, Zheng JZ, Liu LZ et al. Downregulation of ATG14 by EGR1-miR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy. Autophagy. 2015; 11(2): 373-84.
25 Chakraborty PK, Mustafi SB, Xiong X, Dwivedi SKD, Nesin V, Saha S et al. MICU1 drives glycolysis and chemoresistance in ovarian cancer. Nat Commun. 2017; 8: 14634.
26 Lee KY, Sharma R, Gase G, Ussar S, Li Y, Welch L et al. Tbx15 defines a glycolytic subpopulation and white adipocyte heterogeneity. Diabetes. 2017; 66(11): 2822-9.
27 Wang X, Zhang F, Wu XR. Inhibition of pyruvate kinase M2 markedly reduces chemoresistance of advanced bladder cancer to cisplatin. Sci Rep. 2017; 7: 45983.
28 Caetano-Pinto P, Jansen J, Assaraf YG, Masereeuw R. The importance of breast cancer resistance protein to the kidneys excretory function and chemotherapeutic resistance. Drug Resist Updat. 2017; 30: 15-27.
29 Arribas J, Cajuso T, Rodio A, Marcos R, Leonardi A, Velázquez A. NF-κB mediates the expression of TBX15 in cancer cells. PLoS One. 2016; 11(6): e0157761.
30 Xie VK, Li Z, Yan Y, Jia Z, Zuo X, Ju Z et al. DNA-methyltransferase 1 induces dedifferentiation of pancreatic cancer cells through silencing of kruppel-like factor 4 expression. Clin Cancer Res. 2017; 23(18): 5585-97.
31 Yu T, Guo F, Yu Y, Sun T, Ma D, Han J, et al. Fusobacterium nucleatum promotes chemoresistance to colorectal cancer by modulating autophagy. Cell. 2017;170(3):548-63.
32 Bartel DP. Metazoan microRNAs. Cell. 2018; 173(1): 20-51.
33 Schiewer MJ, Knudsen KE. Not so fast: cultivating miRs as Kinks in the chain of the cell cycle. Cancer Cell. 2017; 31(4): 471-3.
34 Enam C, Geffen Y, Ravid T, Gardner RG. Protein quality control degradation in the nucleus. Annu Rev Biochem. 2018; 87: 725-49.