A Comparative Analysis of the Outcome of Malaria Case Surveillance Strategies in Sri Lanka in the Prevention of Re-establishment Phase
Background
Sri Lanka sustained its malaria-free status by implementing, among other interventions, three core case detection strategies. The outcomes of these strategies - namely Passive Case Detection (PCD) and, under the overall strategy of Active Case Detection (ACD), Reactive Case Detection (RACD) and Proactive Case Detection (PACD) - were analysed in terms of their effectiveness in detecting malaria infections for the period from 2017-2019.
Methods
Comparisons were made between the surveillance methods and between years, based on data obtained from the national malaria database and individual case reports of malaria patients. The number of blood smears examined microscopically was used as the measure of the volume of tests conducted. The yield from each case detection method was calculated as the proportion of blood smears which were positive for malaria. Within RACD and PACD, the yield of sub categories of travel cohorts and spatial cohorts was ascertained for 2019.
Results
A total of 158 malaria cases were reported in 2017-2019, during which between 666,325-725,149 blood smears were examined each year: PCD detected 95.6%, with a yield of 16.1 cases per 100,000 blood smears examined, making it the most effective case detection strategy, while RACD and PACD produced a yield of 11.2 and 0.3 respectively. The yield of screening the sub category of travel cohorts was very high for RACD and PACD being 806.5 and 44.9 malaria cases per 100,000 smears respectively. Despite over half of the blood smears examined being obtained by screening spatial cohorts within RACD and PACD, the yield of both was zero over all three years.
Conclusions
The PCD arm of case surveillance is the most effective, and therefore, has to continue and be further strengthened as the mainstay in malaria surveillance. Focus on travel cohorts within RACD and PACD should be even greater. Screening of spatial cohorts, on a routine basis and solely because people are resident in previously malarious areas, may be wasteful, except in situations where the risk of local transmission is very high, or is imminent.
Figure 1
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On 09 Feb, 2021
On 01 Feb, 2021
On 01 Feb, 2021
On 01 Feb, 2021
On 01 Feb, 2021
Posted 23 Dec, 2020
On 25 Jan, 2021
Received 24 Jan, 2021
Received 16 Jan, 2021
Received 16 Jan, 2021
On 06 Jan, 2021
On 05 Jan, 2021
Invitations sent on 25 Dec, 2020
On 25 Dec, 2020
On 13 Dec, 2020
On 10 Dec, 2020
On 10 Dec, 2020
On 09 Dec, 2020
A Comparative Analysis of the Outcome of Malaria Case Surveillance Strategies in Sri Lanka in the Prevention of Re-establishment Phase
On 09 Feb, 2021
On 01 Feb, 2021
On 01 Feb, 2021
On 01 Feb, 2021
On 01 Feb, 2021
Posted 23 Dec, 2020
On 25 Jan, 2021
Received 24 Jan, 2021
Received 16 Jan, 2021
Received 16 Jan, 2021
On 06 Jan, 2021
On 05 Jan, 2021
Invitations sent on 25 Dec, 2020
On 25 Dec, 2020
On 13 Dec, 2020
On 10 Dec, 2020
On 10 Dec, 2020
On 09 Dec, 2020
Background
Sri Lanka sustained its malaria-free status by implementing, among other interventions, three core case detection strategies. The outcomes of these strategies - namely Passive Case Detection (PCD) and, under the overall strategy of Active Case Detection (ACD), Reactive Case Detection (RACD) and Proactive Case Detection (PACD) - were analysed in terms of their effectiveness in detecting malaria infections for the period from 2017-2019.
Methods
Comparisons were made between the surveillance methods and between years, based on data obtained from the national malaria database and individual case reports of malaria patients. The number of blood smears examined microscopically was used as the measure of the volume of tests conducted. The yield from each case detection method was calculated as the proportion of blood smears which were positive for malaria. Within RACD and PACD, the yield of sub categories of travel cohorts and spatial cohorts was ascertained for 2019.
Results
A total of 158 malaria cases were reported in 2017-2019, during which between 666,325-725,149 blood smears were examined each year: PCD detected 95.6%, with a yield of 16.1 cases per 100,000 blood smears examined, making it the most effective case detection strategy, while RACD and PACD produced a yield of 11.2 and 0.3 respectively. The yield of screening the sub category of travel cohorts was very high for RACD and PACD being 806.5 and 44.9 malaria cases per 100,000 smears respectively. Despite over half of the blood smears examined being obtained by screening spatial cohorts within RACD and PACD, the yield of both was zero over all three years.
Conclusions
The PCD arm of case surveillance is the most effective, and therefore, has to continue and be further strengthened as the mainstay in malaria surveillance. Focus on travel cohorts within RACD and PACD should be even greater. Screening of spatial cohorts, on a routine basis and solely because people are resident in previously malarious areas, may be wasteful, except in situations where the risk of local transmission is very high, or is imminent.
Figure 1
Figure 2