In this study, we investigated the mathematical model for cancer treatment. The model takes into account the interaction of the cancer cells with the immune system and the treatment that combined unlicensed dendritic cells and anti-VEGF. We propose a new non-standard protocol for the treatment of cancer. In addition, the mathematical model includes equations of the variability of the treatments unlicensed dendritic cells and anti-VEGF as a function of the time and dependence on the Length of tumor vasculature.