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Research
New Ther1-derived SINE Squam3 in Scaled Reptiles
Nikita S Vassetzky
Engelhardt Institute of Molecular Biology, Moscow, Russia
Corresponding Author
ORCiD: https://orcid.org/0000-0003-4453-4963
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
SINEs compose a significant part of animal genomes and are used to study the evolution of taxa. Despite significant advances in SINE studies in vertebrates and higher eukaryotes in general, their own evolution is poorly understood.
Results
We have found and described in detail a new SINE family Squam3 specific for scaled reptiles (Squamata). The subfamilies of this SINE demonstrate different distribution in the genomes of squamates, which together with the data on similar SINEs in the tuatara allowed us to propose a scenario of their evolution in the context of reptilian evolution.
Conclusions
Ancestral SINEs preserved in small numbers in most genomes can give rise to taxon-specific SINE families. Analysis of this aspect of SINEs can shed light on the history and mechanisms of SINE variation in reptilian genomes.
Keywords
SINEs, retrotransposons, Squamata, Reptilia, evolution
Figure 1
Figure 2
Figure 3
This is a list of supplementary files associated with this preprint. Click to download.
- FigS1.pdf
Green, Squam3A; red, Squam3B; blue - Suam3C. Species designations are: Squam3EmA, Eublepharis macularius; Squam3GjA, Gekko japonicus; Squam3PpA, Paroedura picta; Squam3Vk, Varanus komodoensis; Squam3Ch, Crotalus horridus; Squam3Pt, Pseudonaja textilis; Squam3Cp, Crotalus pyrrhus; Squam3Pg, Pantherophis guttatus; Squam3Nn, Naja naja; Squam3Oh, Ophiophagus hannah; Squam3Pmc, Protobothrops mucrosquamatus; Squam3Ts, Thamnophis sirtalis; Squam3Hc, Hydrophis cyanocinctus; Squam3Te, Thamnophis elegans; Squam3Pf, Protobothrops flavoviridis; Squam3Po, Pantherophis obsoletus; Squam3Cv, Crotalus viridis; Squam3Hh, Hydrophis hardwickii; Squam3Tb, Thermophis baileyi; Squam3Vb, @@@Vipera berus; Squam3Ej Emydocephalus ijimae; Squam3Hm Hydrophis melanocephalus; Squam3Ll Laticauda laticaudata; Squam3Lc Laticauda colubrina; Squam3Ns Notechis scutatus; Squam3Pr Protobothrops mucrosquamatus; Squam3PbC Python bivittatus; Squam3DvB Darevskia valentini; Squam3LbB Lacerta bilineata; Squam3LaB Lacerta agilis; Squam3LvB Lacerta viridis; Squam3PmB Podarcis muralis; Squam3ZvB Zootica vivipara; Squam3GjB Gekko japonicus; Squam3PpB Paroedura picta; Squam3PpB3 Paroedura picta; Squam3GjB3 Gekko japonicus; Squam3EmB Eublepharis macularius; Squam3SmB Salvator merianae.
- TableS1.docx
- TableS2.doc
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Peer Review Timeline
CURRENT STATUS: Under Revision
Version 1
Posted 28 Dec, 2020
No community comments so far
Review #2 received
Received 05 Jan, 2021
Editorial decision: Major revision
On 05 Jan, 2021
Reviewer #2 agreed
On 24 Dec, 2020
Review #1 received
Received 22 Dec, 2020
Reviewer #1 agreed
On 17 Dec, 2020
Editor assigned
On 16 Dec, 2020
Reviewers invited
Invitations sent on 16 Dec, 2020
Submission checks complete
On 16 Dec, 2020
Editor invited
On 16 Dec, 2020
First submitted
On 15 Dec, 2020
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This preprint is under consideration at Mobile DNA. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
New Ther1-derived SINE Squam3 in Scaled Reptiles
Nikita S Vassetzky
Engelhardt Institute of Molecular Biology, Moscow, Russia
Corresponding Author
ORCiD: https://orcid.org/0000-0003-4453-4963
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Revision
Version 1
Posted 28 Dec, 2020
No community comments so far
Review #2 received
Received 05 Jan, 2021
Editorial decision: Major revision
On 05 Jan, 2021
Reviewer #2 agreed
On 24 Dec, 2020
Review #1 received
Received 22 Dec, 2020
Reviewer #1 agreed
On 17 Dec, 2020
Editor assigned
On 16 Dec, 2020
Reviewers invited
Invitations sent on 16 Dec, 2020
Submission checks complete
On 16 Dec, 2020
Editor invited
On 16 Dec, 2020
First submitted
On 15 Dec, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
SINEs compose a significant part of animal genomes and are used to study the evolution of taxa. Despite significant advances in SINE studies in vertebrates and higher eukaryotes in general, their own evolution is poorly understood.
Results
We have found and described in detail a new SINE family Squam3 specific for scaled reptiles (Squamata). The subfamilies of this SINE demonstrate different distribution in the genomes of squamates, which together with the data on similar SINEs in the tuatara allowed us to propose a scenario of their evolution in the context of reptilian evolution.
Conclusions
Ancestral SINEs preserved in small numbers in most genomes can give rise to taxon-specific SINE families. Analysis of this aspect of SINEs can shed light on the history and mechanisms of SINE variation in reptilian genomes.
Figure 1
Figure 2
Figure 3