Hyperlipidemia is associated with tendon disorders and biomechanical changes through tissue deposition. In the present study, we seek the relation of plantar fasciitis (PF) with lipid profile parameters and fasting blood sugar (FBS) levels.
In a case-control study, we enrolled 68 patients with a clinical diagnosis of PF in the case group and 136 individuals without PF in the control group. Patients’ height, weight, body mass index (BMI), FBS, lipid profile including low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol, and triglyceride (TG) laboratory tests were also checked as the main study variables to be compared between the two groups. The mean difference of each variable between the two case and control groups was tested using an independent t-test. Correlation coefficient analyses were used to calculate the correlation of patients’ BMI with lipid profile and FBS levels to evaluate the BMI variable as a confounder.
Patients with PF had higher levels of total cholesterol (p=0.001), LDL (P= 0.004), and TG (P=0.02). HDL (P=0.13) and FBS (P=0.24) levels did not differ between two groups. Odds ratio calculation showed that patients with serum levels of LDL >130 mg/dl and total cholesterol > 200 mg/dl were 3.7 and 1.8 times more likely to develop PF, respectively. We found no association between lipid profile parameters and BMI in either of the two groups.
Our findings show higher levels of serum lipid profile parameters in patients with PF. Thus, it supports the modification of LDL, TC, TG, and glucose levels when managing PF.
The study does not include intervention.