1. Chaudhry, Q., Scotter, M., Blackburn, J., Ross, B., Boxall, A., Castle, L., Aitken, R., & Watkins, R. (2008). Applications and implications of nanotechnologies for the food sector. In Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment (Vol. 25, Issue 3, pp. 241–258). https://doi.org/10.1080/02652030701744538
2. Wu, H., Liu, W., Shi, L. et al. Comparative Genomic and Regulatory Analyses of Natamycin Production of Streptomyces lydicus A02. Sci Rep 7, 9114 (2017). https://doi.org/10.1038/s41598-017-09532-3
3. Parada, J. L., Caron, C. R., Medeiros, A. B. P., & Soccol, C. R. (2007). Bacteriocins from lactic acid bacteria: Purification, properties and use as biopreservatives. Brazilian Archives of Biology and Technology, 50(3), 521–542. https://doi.org/10.1590/s1516-89132007000300018
4. S. Karthick Raja Namasivayam S. Samydurai, Vinay Kumar Pandey. 2016. Influence of Algal Based Protein Nanoparticles Loading on Antibacterial Activity, In Vitro Drug Release and Cytotoxicity of Cephalosporin Derivative. Asian Journal of Pharmaceutics 10 (4); 595-599
5. Namasivayam, S. K. R., Angel, J. C. R., Bharani, R. S. A., & Karthik, M. Y. (2014). Effect of media on bacteriocin production by Lactobacillus brevis and evaluation of antibacterial activity. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 5(5), 1129–1136.
6. Du, Y. L. et al. Identification of a novel Streptomyces chattanoogensis L10 and enhancing its natamycin production by overexpressing positive regulation scnRII. J. Microbiol. 47, 506–513 (2009).
7. Pedersen J.1992. Natamycin as a fungicide in agar media. Applied and Environmental Microbiology,58; 1064-1066
8. Leyva Salas, Marcia et al. “Antifungal Microbial Agents for Food Biopreservation-A Review.” Microorganisms vol. 5,3 37. 8 Jul. 2017, doi:10.3390/microorganisms5030037
9. de Boer, E. & Stolk-Horsthuis, M. (1977) Sensitivity to natamycin (pimaricin) of fungi isolated in cheese warehouses. J. Food Prot., 40, 533–536.
10. Aparicio, J.F., Colina, A.J., Ceballos, E. & Martin, J.F. (1999) The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. J. Biochem. Mol. Biol., 274, 10133–10139.
11. Te Welscher, Y. M., Ten Napel, H. H., Balagué, M. M., Souza, C. M., Riezman, H., De Kruijff, B., & Breukink, E. (2008). Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilising the membrane. Journal of Biological Chemistry, 283(10), 6393–6401. https://doi.org/10.1074/jbc.M707821200
12. Delattin, N., Cammue, B. P., & Thevissen, K. (2014). Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms. Future Medicinal Chemistry, 6(1), 77–90. https://doi.org/10.4155/fmc.13.189
13, Te Welscher, Y. M., Van Leeuwen, M. R., De Kruijff, B., Dijksterhuis, J., & Breukink, E. (2012). Polyene antibiotic that inhibits membrane transport proteins. Proceedings of the National Academy of Sciences of the United States of America, 109(28), 11156–11159. https://doi.org/10.1073/pnas.1203375109
14. Lalitha, P., Shapiro, B. L., Srinivasan, M., Prajna, N. V., Acharya, N. R., Fothergill, A. W., Ruiz, J., Chidambaram, J. D., Maxey, K. J., Hong, K. C., McLeod, S. D., & Lietman, T. M. (2007). Antimicrobial susceptibility of Fusarium, Aspergillus, and other filamentous fungi isolated from keratitis. Archives of Ophthalmology, 125(6), 789–793. https://doi.org/10.1001/archopht.125.6.789
15. Lalitha, P., Vijaykumar, R., Prajna, N. V., & Fothergill, A. W. (2008). In vitro natamycin susceptibility of ocular isolates of Fusarium and Aspergillus species: Comparison of commercially formulated natamycin eye drops to pharmaceutical-grade powder. Journal of Clinical Microbiology, 46(10), 3477–3478. https://doi.org/10.1128/JCM.00610-08
16. Xu, Y., Pang, G., Gao, C., Zhao, D., Zhou, L., Sun, S., & Wang, B. (2009). In vitro comparison of the efficacies of natamycin and silver nitrate against ocular fungi. Antimicrobial Agents and Chemotherapy, 53(4), 1636–1638. https://doi.org/10.1128/AAC.00697-08
17. Brothers AM, Wyatt RD. The antifungal activity of natamycin toward molds isolated from commercially manufactured poultry feed. Avian Dis. 2000 Jul-Sep;44(3):490-7. PMID: 1100699
18. Al-Hatmi, A. M. S., Meletiadis, J., Curfs-Breuker, I., Bonifaz, A., Meis, J. F., & De Hoog, G. S. (2016). In vitro combinations of natamycin with voriconazole, itraconazole and micafungin against clinical Fusarium strains causing keratitis. Journal of Antimicrobial Chemotherapy, 71(4), 953–955. https://doi.org/10.1093/jac/dkv421
19. Rees, C. A., Bao, R., Zegans, M. E., & Cramer, R. A. (2019). Natamycin and voriconazole exhibit synergistic interactions with non-antifungal ophthalmic agents against Fusarium species ocular isolates. Antimicrobial Agents and Chemotherapy, 63(7), e02505-18. https://doi.org/10.1128/AAC.02505-18
20. Abhishakth Gerhardt, B.S., Bhuvaneshwari., Sravani Marpaka. (2019). Effect of topical 5% Natamycin in treatment of fungal corneal ulcer: A prospective study in a tertiary care teaching hospital in Telangana. MedPulse International Journal of Pharmacology, 12(1), 1-5.
21/ Jiang, T., Tang, J., Wu, Z., Sun, Y., Tan, J., & Yang, L. (2020). The combined utilisation of Chlorhexidine and Voriconazole or Natamycin to combat Fusarium infections. BMC Microbiology, 20(1), 1–6. https://doi.org/10.1186/s12866-020-01960-y
22. Liu, J., Wang, J., Song, H., Zhang, Z., Xu, X., Ji, X., & Shi, X. (2019). Antifungal Activity and Mechanisms of Natamycin Against Colletotrichum gloeosporioides in Postharvest Mango Fruit. Chinese Bulletin of Botany, 54(4), 455.
23. Prakash, J., Vignesh, K., Anusuya, T., Kalaivani, T., Ramachandran, C., Sudha, R. R., ... & DevanandVenkatasubbu, G. (2019). Application of Nanoparticles in Food Preservation and Food Processing. Journal of Food Hygiene and Safety, 34(4), 317–324. https://doi.org/10.13103/jfhs.2019.34.4.317
24. Fernandes, A. R., Mendonça-Martins, I., Santos, M. F. A., Raposo, L. R., Mendes, R., Marques, J., Romão, C. C., Romão, M. J., Santos-Silva, T., & Baptista, P. V. (2020). Improving the Anti-inflammatory Response via Gold Nanoparticle Vectorization of CO-Releasing Molecules. ACS Biomaterials Science and Engineering, 6(2), 1090–1101. https://doi.org/10.1021/acsbiomaterials.9b01936
25. Karthick Raja Namasivayam, S., Arvind Bharani, R. S., & Karunamoorthy, K. (2018). Insecticidal fungal metabolites fabricated chitosan nanocomposite (IM-CNC) preparation for the enhanced larvicidal activity - An effective strategy for green pesticide against economic important insect pests. International Journal of Biological Macromolecules, 120, 921–944. https://doi.org/10.1016/j.ijbiomac.2018.08.130
26. Shahbazi, Y., & Shavisi, N. (2019). Current advancements in applications of chitosan based nano-metal oxides as food preservative materials. Nanomedicine Research Journal, 4(3), 122–129. https://doi.org/10.22034/NMRJ.2019.03.001
27. Mohammadi, A., Hashemi, M., & Hosseini, S. M. (2015). Nanoencapsulation of Zataria multiflora essential oil preparation and Characterisation with enhanced antifungal activity for controlling Botrytis cinerea, the causal agent of gray mould disease. Innovative Food Science and Emerging Technologies, 28, 73–80. https://doi.org/10.1016/j.ifset.2014.12.011
28. Badawy, M. E. I., Lotfy, T. M. R., & Shawir, S. M. S. (2019). Preparation and antibacterial activity of chitosan-silver nanoparticles for application in preservation of minced meat. Bulletin of the National Research Centre, 43(1), 1–14. https://doi.org/10.1186/s42269-019-0124-8
29. Kiss. (2020). Nanotechnology in food systems: A review. Acta Alimentaria, 49(4), 460–474. https://doi.org/10.1556/066.2020.49.4.12
30. Akhavan, S., Assadpour, E., Katouzian, I., & Jafari, S. M. (2018). Lipid nano scale cargos for the protection and delivery of food bioactive ingredients and nutraceuticals. Trends in Food Science and Technology, 74, 132–146. https://doi.org/10.1016/j.tifs.2018.02.001
31. Butnaru, E., Cheaburu, C. N., Yilmaz, O., Pricope, G. M., & Vasile, C. (2016). Poly (vinyl alcohol)/chitosan/montmorillonite nanocomposites for food packaging applications: Influence of montmorillonite content. High Performance Polymers, 28(10), 1124–1138. https://doi.org/10.1177/0954008315617231
32. Leyva Salas, M., Mounier, J., Valence, F., Coton, M., Thierry, A., & Coton, E. (2017). Antifungal Microbial Agents for Food Biopreservation—A Review. Microorganisms, 5(3), 37. https://doi.org/10.3390/microorganisms5030037
33. Sagun-bella, K. Q. De, Agahan, A. L. D., Cubillan, L. D. P., Carino, N. S., & Mesa-rodriguez, R. De. (2013). Antifungal Activity of Voriconazole on Local Isolates: an In-vitro Study. Philipp J Ophthalmol, 38 (June 2013), 29–34.
34. Fahimi, S., & Ghorbani, H. R. (2019). The preparation of chitosan-Ag nanocomposite for food packaging. J. Nanoanalysis, 6(2), 115–120. http://creativecommons.org/licenses/by/4.0/.
35. M Ahmed, E., Saber, D., Abd Elaziz, K., Alghtani, A. H., Felemban, B. F., Ali, H. T., & Megahed, M. (2021). Chitosan-based nanocomposites: Preparation and Characterisation for food packing industry. Materials Research Express, 8(2), 25017. https://doi.org/10.1088/2053-1591/abe791
36. Hooda, R., Batra, B., Kalra, V., Rana, J. S., & Sharma, M. (2018). Chitosan-Based Nanocomposites In Food Packaging. In Bio-based Materials for Food Packaging: Green and Sustainable Advanced Packaging Materials (pp. 269–285). Springer. https://doi.org/10.1007/978-981-13-1909-9_12
37. Masheane, M., Nthunya, L., Malinga, S., Nxumalo, E., Barnard, T., & Mhlanga, S. (2016). Antimicrobial properties of chitosan-alumina/f-MWCNT nanocomposites. Journal of Nanotechnology, 2016, 8.
38. Meghani, N., Dave, S., Kumar, A. (2019). Nanofood and its application–A review. BAOJ Nanotech., 5(1), 1–16.
39. Shanmuga Priya, D., Suriyaprabha, R., Yuvakkumar, R., & Rajendran, V. (2014). Chitosan-incorporated different nanocomposite HPMC films for food preservation. Journal of Nanoparticle Research, 16(2), 1–16. https://doi.org/10.1007/s11051-014-2248-y
40. Kumar, S., Ye, F., Dobretsov, S., & Dutta, J. (2019). Chitosan nanocomposite coatings for food, paints, and water treatment applications. Applied Sciences (Switzerland), 9(12), 2409. https://doi.org/10.3390/app9122409
41. Padmanabhan, V. P., Kulandaivelu, R., & Nellaiappan, S. N. T. S. (2018). New core-shell hydroxyapatite/um-Acacia nanocomposites for drug delivery and tissue engineering applications. Materials Science and Engineering C, 92, 685–693. https://doi.org/10.1016/j.msec.2018.07.018
42. Bhatta, R. S., Chandasana, H., Chhonker, Y. S., Rathi, C., Kumar, D., Mitra, K., & Shukla, P. K. (2012). Mucoadhesive nanoparticles for prolonged ocular delivery of natamycin: In vitro and pharmacokinetics studies. International Journal of Pharmaceutics, 432(1–2), 105–112. https://doi.org/10.1016/j.ijpharm.2012.04.060
43. Boskovic, M., Glisic, M., Djordjevic, J., Vranesevic, J., Djordjevic, V., & Baltic, M. Z. (2019). Preservation of meat and meat products using nanoencapsulated thyme and oregano essential oils. IOP Conference Series: Earth and Environmental Science, 333(1), 12038. https://doi.org/10.1088/1755-1315/333/1/012038
44. Ding, S. J., & Zhu, J. (2015). Tuning the surface enhanced Raman scattering activity of gold nanocubes by silver coating. Applied Surface Science, 357, 487–492. https://doi.org/10.1016/j.apsusc.2015.09.077
45. Coman, C., Leopold, L. F., Rugina, O. D., Diaconeasa, Z. O. R. I. Ţ. A., Bolfa, P. F., Leopold, N. & Socaciu, C. A. R. M. E. N. (2015). Protein-capped gold nanoparticles obtained by a green synthesis method. Studia UBB Chemia, 60, 119.
46. Narendrakumar, G., Karthick Raja Namasivayam, S., Manikanta, M., Saha, M., Dasgupta, T., Divyasri, N., Anusha, C., Arunkumar, B., & Preethi, T. V. (2018). Enhancement of biocontrol potential of biocompatible bovine serum albumin (BSA) based protein nanoparticles loaded bacterial chitinase against major plant pathogenic fungi Alternaria alternata. Biocatalysis and Agricultural Biotechnology, 15, 219–228. https://doi.org/10.1016/j.bcab.2018.05.015
47. AOAC (2000) Official Methods of Analysis. 17th Edition, The Association of Official Analytical Chemists, Gaithersburg, MD, USA. Methods 925.
48. Gustavsson, J., Cederberg, C., Sonesson, U., van Otterdijk, R., & Meybeck, A. (2011). Global food losses and food waste: extent, causes and prevention. International Congress: Save Food! 38. http://www.fao.org/fileadmin/user_upload/ags/publications/GFL_web.pdf
49. Karthick Raja Namasivayam, S., Arul Maximus Rabel., Prasana, R., Arvind Bharani, R. S., Valli Nachiyar, C. (2021). Gum acacia PEG iron oxide nanocomposite (GA-PEG-IONC) induced pharmacotherapeutic activity on the Las R gene expression of Pseudomonas aeruginosa and HOXB13 expression of prostate cancer (Pc 3) cell line. A green therapeutic approach of molecular mechanism inhibition. International Journal of Biological Macromolecules, 190, 940-959.
50. Türe, H., Eroglu, E., Soyer, F., & Özen, B. (2008). Antifungal activity of biopolymers containing natamycin and rosemary extract against Aspergillus niger and Penicillium roquefortii. International Journal of Food Science and Technology, 43(11), 2026–2032.
51. Krishnan, G. S., Rajagopal, V., Antony Joseph, S. R., Sebastian, D., Savarimuthu, I., Karthick Raja Namasivayam, S., & Thobias, A. F. (2017). In vitro, in silico and in vivo antitumor activity of crude methanolic extract of tetilla dactyloidea (carter, 1869) on den induced hcc in a rat model. Biomedicine and Pharmacotherapy, 95, 795–807. https://doi.org/10.1016/j.biopha.2017.08.054
52. Delattin, N., Cammue, B. P., & Thevissen, K. (2014). Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms. Future Medicinal Chemistry, 6(1), 77–90. https://doi.org/10.4155/fmc.13.189
53. Ighodaro, O. M., & Akinloye, O. A. (2018). First line defence antioxidants superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid. Alexandria Journal of Medicine, 54(4), 287-293. DOI: 10.1016/j.ajme.2017.09.001
54. Deponte, M. (2013). Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes. Biochimica et Biophysica Acta, 1830(5), 3217-66. DOI: 10.1016/j.bbagen.2012.09.018
55. Aggarwal, B. B., & Shishodia, S. (2006). Molecular targets of dietary agents for prevention and therapy of cancer. Biochemical Pharmacology, 71(10), 1397-1421. DOI: 10.1016/j.bcp.2006.02.009
56. Casagrande, J. C., Macorini, L. F. B., Antunes, K. A., Santos, U. P. D., Campos, J. F., Dias-Júnior, N. M., & de Picoli Souza, K . (2014). Antioxidant and cytotoxic activity of hydroethanolic extract from Jacaranda decurrens leaves. PLoS ONE, 9(11), e112748. DOI: 10.1371/journ al.pone.0112748
57. Huang, C., Lai, C., Xu, P., Zeng, G., Huang, D., Zhang, J., Zhang, C., Cheng, M., Wan, J., & Wang, R. (2017). Lead-induced oxidative stress and antioxidant response provide insight into the tolerance of Phanerochaete chrysosporium to lead exposure. Chemosphere, 187, 70-77. DOI: 10.1016/j.chemosphere.2017.08.104.
58. Saleh, H. H., Ali, Z. I., & Afify, T. A. (2016) Synthesis of Ag/PANI core shell nanocomposites using ionising radiation. Advanced Polymer Technology, 35(3), 335–344. DOI:10.1002/adv.21560.
59. Karthick Raja Namasivayam, S., Venkatachalam, G., & Bharani, R. S. A. (2021). Noteworthy enhancement of wound-healing activity of Triphala biomass metabolite-loaded hydroxyapatite nanocomposite. Applied Nanoscience, 11(5), 1511–1530. DOI: 10.1007/s13204-021-01813-8.
60. Villamizar-Gallardo, R., Cruz, J. F. O., & Ortíz-Rodriguez O. O. (2016). Fungicidal effect of silver nanoparticles on toxigenic fungi in cocoa, Pesquisa Agropecuária Brasileira. 51(12), 1929-1936, DOI: 10.1590/S0100-204X2016001200003
61. Akpinar, I., Unal, M., & Sar, T. (2021). Potential antifungal effects of silver nanoparticles (AgNPs) of different sizes against phytopathogenic Fusarium oxysporum f. sp. radicis‑lycopersici (FORL) strains. SN Applied Sciences, 3(4), 506. DOI: 10.1007/s42452-021-04524-5
62. Zhang, F., Liu, X., Pentok, M., Sauli, E., He, N., Zen, X., Li, X., & Li, T. (2019). Molecular mechanism and changes of antioxidant enzyme in ZnO nanoparticles against fungus. Journal of Biomedical Nanotechnology, 15(4), 647-661. DOI: 10.1166/jbn.2019.2718.
63. Basu, A., Ray, S., Chowdhury, S., Sarkar, A., Mandal, D. P., Bhattacharjee, S., & Kundu, S. (2018). Evaluating the antimicrobial, apoptotic, and cancer cell gene delivery properties of protein-capped gold nanoparticles synthesised from the edible mycorrhizal fungus Tricholoma crissum. Nanoscale Research Letters, 13, 154. DOI: 10.1186/s11671-018-2561-y
64. Rahimzadeh Torabi, L., & Doudi. M. (2016). The effect of gold nanoparticles compared to dioxide titanium nanoparticles on vital factors of isolated Candida albicans in patients with oral candidiasis in vitro. Zahedan Journal of Research in Medical Sciences. 18(12), e5666.
DOI : 10.17795/zjrms-5666
65. Folorunso, A., Akintelu, S., Oyebamiji, A. K., Ajayi, S., Abiola, B., Abdusalam, I., Morakinyo A. (2019). Biosynthesis, Characterisation and antimicrobial activity of gold nanoparticles from leaf extracts of Annona muricata. Journal of Nanostructure in Chemistry, 9(2), 111–117. DOI: 10.1007/s40097-019-0301-1
66. Hamad, K. M., Mahmoud, N. N., Al-Dabash, S., Al-Samad, L. A., Abdallah, M., & Al-Bakri, A. G. (2020). Fluconazole conjugated-gold nanorods as an antifungal nanomedicine with low cytotoxicity against human dermal fibroblasts. RSC Adv, 10, 25889-25897. DOI: 10.1039/ d0ra00297f
67. Lipovsky, A., Nitzan, Y., Gedanken, A., & Lubar, R. (2011). Antifungal activity of ZnO nanoparticles—the role of ROS mediated cell injury. Nanotechnology, 22, 105101.
68. Kim, S.W., Jung, J.H., Lamsal, K., Kim, Y. S., Min, J. S. & Lee, Y. S. (2012). Antifungal effects of silver nanoparticles (AgNPs) against various plant pathogenic fungi. Mycobiology 40(1), 53-58. DOI: 10.5941/MYCO.2012.40.1.053.
69. A. Jebali, Hajjar, F. H. E., Pourdanesh, F., Hekmatimoghaddam, S., Kazemi, B., Masoudi, A., Daliri, K., Sedighi., N. (2013). Silver and gold nanostructures: antifungal property of different shapes of these nanostructures on Candida species. Medical Mycology, 52(1), 65–72. DOI: 10.3109/13693786.2013.822996
70. Eskandari-Nojedehi, M., Jafarizadeh-Malmiri, H., & Rahbar-Shahrouzi, J. (2018). Hydrothermal green synthesis of gold nanoparticles using mushroom (Agaricus bisporus) extract: physico-chemical characteristics and antifungal activity studies. Green Processing and Synthesis, 7(1), 38–47. DOI: 10.1515/gps-2017-0004
71. Chen, J., Wu, L., Lu, M., Lu, S., Li, Z., & Ding, W. (2020). Comparative Study on the Fungicidal Activity of Metallic MgO Nanoparticles and Macroscale MgO Against Soilborne Fungal Phytopathogens. Frontiers in Microbiology, 11, 365. DOI: 10.3389/fmicb.2020.00365
72. Rahimi, H., Roudbarmohammadi, S., Hamid Delavari, H., Roudbary, M. (2019). Antifungal effects of indolicidin-conjugated gold nanoparticles against fluconazole-resistant strains of Candida albicans isolated from patients with burn infection. International Journal of Nanomedicine, 14, 5323–5338. DOI: 10.2147/IJN.S207527.