This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research Article
Pui Kwan Chan
Department of Family Medicine and General Outpatient Clinics (GOPCs), Kowloon Central Cluster (KCC), Hospital Authority (HA),Hong Kong
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
With the ageing population, osteoporosis is increasingly becoming a global health concern. Previous research showed that management of osteoporosis in Hong Kong had been suboptimal. In view of the need to provide quality care to osteoporotic patients, a Multidisciplinary Osteoporosis Clinic (MOC) organized by primary care physicians was set up in a public primary care clinic. This study aimed to explore the clinical effectiveness of MOC.
Methods
We performed a retrospective case series study. All osteoporotic patients who had attended MOC during the period 1 January 2015 to 31 December 2018 were included. Changes in Dual X-ray absorptiometry (DEXA) T-score of recruited patients after two years of management at MOC were analysed. Subgroup analyses of the 2-year interval DEXA T-score changes among patient with or without history of fragility fracture, and among patients with or without pharmacological treatment , were performed. Serial interval DEXA T-score changes of recruited patients who had completed 5 years of bisphosphonate treatment were also analysed. Paired Student’s t test was used to analyze the interval DEXA T-score changes.
Results
Totally 186 osteoporotic patients were recruited. After two years of management at MOC, the T-score at lumbar spine and femoral neck were improved, from -2.71±0.76 to -2.35±0.83 and -2.40±0.75 to -2.10±0.76 respectively, P<0.001. For subgroup analysis on patients with or without history of fragility fracture and patients with or without bisphosphonate treatment, improvement in T-scores of both lumbar and femoral neck were all significant at two years, P<0.05.
Among those who had completed 5 years of bisphosphonate treatment, progressive improvement in T-scores of both lumbar and femoral neck were observed, with P <0.001.
Conclusion
MOC run by family physicians in public primary care setting could effectively treat osteoporotic patients with significant improvement in DEXA T-scores.
Keywords
Family physician, osteoporosis, management outcome, T-score
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Loading...
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 31 Dec, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
General Practice
Learn more about our company.
This is a preprint. It has not completed peer review.
Research Article
Pui Kwan Chan
Department of Family Medicine and General Outpatient Clinics (GOPCs), Kowloon Central Cluster (KCC), Hospital Authority (HA),Hong Kong
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 31 Dec, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
General Practice
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
With the ageing population, osteoporosis is increasingly becoming a global health concern. Previous research showed that management of osteoporosis in Hong Kong had been suboptimal. In view of the need to provide quality care to osteoporotic patients, a Multidisciplinary Osteoporosis Clinic (MOC) organized by primary care physicians was set up in a public primary care clinic. This study aimed to explore the clinical effectiveness of MOC.
Methods
We performed a retrospective case series study. All osteoporotic patients who had attended MOC during the period 1 January 2015 to 31 December 2018 were included. Changes in Dual X-ray absorptiometry (DEXA) T-score of recruited patients after two years of management at MOC were analysed. Subgroup analyses of the 2-year interval DEXA T-score changes among patient with or without history of fragility fracture, and among patients with or without pharmacological treatment , were performed. Serial interval DEXA T-score changes of recruited patients who had completed 5 years of bisphosphonate treatment were also analysed. Paired Student’s t test was used to analyze the interval DEXA T-score changes.
Results
Totally 186 osteoporotic patients were recruited. After two years of management at MOC, the T-score at lumbar spine and femoral neck were improved, from -2.71±0.76 to -2.35±0.83 and -2.40±0.75 to -2.10±0.76 respectively, P<0.001. For subgroup analysis on patients with or without history of fragility fracture and patients with or without bisphosphonate treatment, improvement in T-scores of both lumbar and femoral neck were all significant at two years, P<0.05.
Among those who had completed 5 years of bisphosphonate treatment, progressive improvement in T-scores of both lumbar and femoral neck were observed, with P <0.001.
Conclusion
MOC run by family physicians in public primary care setting could effectively treat osteoporotic patients with significant improvement in DEXA T-scores.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Loading...