Category
|
ID
|
Term
|
adj_pval
|
Genes
|
Biological Process
|
GO:0060337
|
type I interferon signaling pathway
|
6.87E-09
|
IFIT3, IFI27, ISG15, OAS3, RSAD2, XAF1, MX1, STAT1, IFI6
|
Cellular CoMolecular Functiononent
|
GO:0005634
|
nucleus
|
1.56E-07
|
PDLIM7, MAF1, TGFB1, ZKSCAN4, PKM, AKT1, USP18, MAZ, ZYX, MX1, BRD8, H1F0, PPP2R1A, RBM42, ACTN4, CIZ1, HERC6, HERC5, SLC3A2, PKN1, RMI1, FLNA, NUCB1, LAP3, G6PD, ARRB2, HSPB1, CMIP, MAPK7, PTOV1, IFIH1, NFKBID, TADA3, ZNF780A, BANF1, MLF2, NR1H2, PFN1, DRAP1, PIR, XAF1, BHLHE40, MT1H, MAFF, MAP2K2, PTPA, SPHK1, KLF16, S100A11, NR4A1, MAFK, STAT1, LGALS9, ZNF628, UBA1, MEX3C, DGKZ, SH3BGRL3, ASNA1
|
Biological Process
|
GO:0009615
|
response to virus
|
4.99E-07
|
IFIT3, IFIH1, DDX60, OAS3, HSPB1, RSAD2, IFI44, MX1, BANF1
|
Biological Process
|
GO:0051607
|
defense response to virus
|
1.08E-06
|
IFIT3, ISG15, DDX60, OAS3, HERC5, RSAD2, IFI44L, MX1, STAT1, GBP1
|
Molecular Function
|
GO:0005515
|
protein binding
|
4.33E-06
|
PRR16, PDLIM7, RAB5C, TGFB1, ZKSCAN4, SHKBP1, PKM, AKT1, USP18, MAZ, ISG15, CLCF1, RNF219, DDX60, MLST8, ZYX, MX1, FMNL1, H1F0, PPP2R1A, RBM42, ACTN4, SOCS3, CIZ1, SLC3A2, HERC5, PKN1, RMI1, JUNB, FLNA, LRRC25, NUCB1, CD37, G6PD, GNB2, ARRB2, CFL2, HSPB1, CMIP, VAMP2, MAPK7, EMP3, PPP1R15A, COPE, GBP1, IFIH1, NFKBID, TADA3, TNFRSF12A, USP5, OAS3, RSAD2, STARD10, NAPA, BANF1, MLF2, NR1H2, PFN1, DRAP1, PIR, BHLHE40, MT1H, C9ORF16, MAP2K2, PTPA, SPHK1, S100A11, NR4A1, MAFK, STAT1, IFIT3, PPP1R9B, APOL1, ZNF217, UBA1, MEX3C, DGKZ, ASNA1, IFI6
|
Cellular CoMolecular Functiononent
|
GO:0005737
|
cytoplasm
|
1.36E-05
|
PDLIM7, IFI44L, MAF1, TGFB1, PKM, AKT1, DDX60, MCOLN1, MLST8, ZYX, MX1, RBM42, ACTN4, SOCS3, HERC6, HERC5, SLC3A2, PKN1, IFI44, PNPLA2, FLNA, LAP3, G6PD, ARRB2, HSPB1, CMIP, MAPK7, SPATS2L, PPP1R15A, UBE2S, OAS3, BANF1, MLF2, NR1H2, PFN1, TPGS1, PIR, MT1H, MAP2K2, PTPA, GIMAP8, SPHK1, S100A11, NR4A1, STAT1, LGALS9, IFIT3, PPP1R9B, UBA1, MEX3C, DGKZ, SH3BGRL3, ASNA1
|
Cellular CoMolecular Functiononent
|
GO:0005829
|
cytosol
|
1.92E-05
|
MIDN, IFIH1, OAS3, NAPA, STARD10, MAF1, BANF1, PKM, AKT1, PFN1, USP18, ISG15, XAF1, MLST8, MX1, FMNL1, PPP2R1A, SOCS3, MAP2K2, GIMAP8, HERC6, SPHK1, HERC5, PKN1, PNPLA2, STAT1, FLNA, IFIT3, G6PD, GNB2, ARRB2, UBA1, HSPB1, MAPK7, VAMP2, TRAPPC1, PPP1R15A, COPE, GBP1
|
Molecular Function
|
GO:0051721
|
protein phosphatase 2A binding
|
6.31E-04
|
AKT1, PTPA, SPHK1, STAT1
|
Biological Process
|
GO:0032515
|
negative regulation of phosphoprotein phosphatase activity
|
8.27E-04
|
PPP1R9B, PTPA, PPP1R15A
|
Biological Process
|
GO:0043154
|
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
9.80E-04
|
AKT1, LAMP3, ARRB2, NR4A1, IFI6
|
Cellular CoMolecular Functiononent
|
GO:0048471
|
perinuclear region of cytoplasm
|
0.001140013
|
PTOV1, LAMP3, GNB2, ACTN4, MAP2K2, HERC5, VAMP2, MAF1, MX1, STAT1, MT1H, FLNA
|
Biological Process
|
GO:0045071
|
negative regulation of viral genome replication
|
0.002093822
|
ISG15, OAS3, RSAD2, MX1
|
Cellular CoMolecular Functiononent
|
GO:0005925
|
focal adhesion
|
0.002278891
|
LAP3, PFN1, GNB2, PDLIM7, ACTN4, MAP2K2, HSPB1, ZYX, FLNA
|
Biological Process
|
GO:1902176
|
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
|
0.003482063
|
AKT1, HSPB1, MAPK7
|
Biological Process
|
GO:0032270
|
positive regulation of cellular protein metabolic process
|
0.004001111
|
NR1H2, AKT1, TGFB1
|
Biological Process
|
GO:0043536
|
positive regulation of blood vessel endothelial cell migration
|
0.006408858
|
AKT1, HSPB1, TGFB1
|
Molecular Function
|
GO:0003725
|
double-stranded RNA binding
|
0.006651476
|
IFIH1, DDX60, OAS3, SLC3A2
|
Cellular CoMolecular Functiononent
|
GO:0031982
|
vesicle
|
0.007093041
|
PKM, AKT1, LAMP3, GNB2, VAMP2
|
Biological Process
|
GO:0035924
|
cellular response to vascular endothelial growth factor stimulus
|
0.009326365
|
AKT1, HSPB1, NR4A1
|
Molecular Function
|
GO:0051015
|
actin filament binding
|
0.009604694
|
FMNL1, PPP1R9B, ACTN4, CFL2, FLNA
|
Cellular CoMolecular Functiononent
|
GO:0015629
|
actin cytoskeleton
|
0.009642609
|
H1F0, PPP1R9B, PDLIM7, ACTN4, CFL2, FLNA
|
Biological Process
|
GO:0033138
|
positive regulation of peptidyl-serine phosphorylation
|
0.010108194
|
AKT1, ARRB2, PPP1R15A, TGFB1
|
Cellular CoMolecular Functiononent
|
GO:0005913
|
cell-cell adherens junction
|
0.012526333
|
PKM, PFN1, SLC3A2, S100A11, ZYX, STAT1, FLNA
|
Molecular Function
|
GO:0019888
|
protein phosphatase regulator activity
|
0.014199861
|
PPP2R1A, PTPA, PPP1R15A
|
Biological Process
|
GO:0032480
|
negative regulation of type I interferon production
|
0.015578596
|
IFIH1, ISG15, HERC5
|