This preprint is under consideration at The Journal of Headache and Pain. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
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Background: Migraine is a primary headache disorder characterized by recurrent attacks that may have a significant impact on patients’ daily life. Treatment options must often be re-evaluated in light of efficacy, tolerability and compliance issues. Few data on commonly applied treatment algorithms and treatment failures have existed in Germany in 2017/2018. The PANORAMA survey was designed to explore and characterize the migraine healthcare landscape and to demonstrate the medical treatment need at that time in Germany.
Methods: Three different questionnaires were used to assess the profile of the 119 participating centers, characterize migraine patients at centers and evaluate qualitative aspects of the current migraine healthcare situation from a physician´s professional perspective. Data were analyzed as observed and summarized by descriptive statistics.
Results: The results demonstrate that once referred to a migraine specialist, the majority of patients continue to be treated at a specialist. At specialized centers, 41.6% of migraine patients receive prophylactic treatment. 45.4% of prophylactic treatments are initiated with a beta-blocker and 28.1% with an anti-epileptic. Pivotal factors to initiate prophylactic treatment are migraine attack frequency and intensity (58.0%). Treatment decisions are largely based on prior / concomitant diseases and physical constitution of the patient (52.1%). Following an inadequate treatment, most patients either switch substance class or discontinue prophylactic treatment.
Conclusions: PANORAMA gives a comprehensive overview of the migraine healthcare landscape in Germany in 2017/2018, elucidates a lack of common treatment algorithms and reveals a high demand for defined therapy strategies and new prophylactic treatment going forwards.
Keywords
Migraine, healthcare systems, headache, patient care, preventive treatment
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CURRENT STATUS: Under Review
Version (no preprint)
Posted 23 May, 2021
Review #2 received
Received 23 May, 2021
Reviewer #2 agreed
On 16 May, 2021
Review #1 received
Received 16 May, 2021
Reviewers invited
Invitations sent on 11 May, 2021
Reviewer #1 agreed
On 11 May, 2021
Editor assigned
On 10 May, 2021
Submission checks complete
On 10 May, 2021
Editor invited
On 10 May, 2021
Editorial decision: Major revision
On 08 Feb, 2021
First submitted
On 21 Dec, 2020
This version was not preprinted
Version (no preprint)
Posted 23 May, 2021
Review #2 received
Received 23 May, 2021
Reviewer #2 agreed
On 16 May, 2021
Review #1 received
Received 16 May, 2021
Reviews received
Received 12 May, 2021
Reviewers invited
Invitations sent on 11 May, 2021
Reviewer #1 agreed
On 11 May, 2021
Editor assigned
On 11 May, 2021
Submission checks complete
On 10 May, 2021
Editor invited
On 10 May, 2021
First submitted
On 09 May, 2021
Editorial decision: Minor revision
On 08 Feb, 2021
This version was not preprinted
Version (no preprint)
Posted 28 Mar, 2021
Editorial decision: Major revision
On 28 Mar, 2021
Review #2 received
Received 27 Mar, 2021
Review #1 received
Received 19 Mar, 2021
Reviewer #2 agreed
On 15 Mar, 2021
Reviewers invited
Invitations sent on 14 Mar, 2021
Reviewer #1 agreed
On 14 Mar, 2021
Editor assigned
On 11 Mar, 2021
Submission checks complete
On 11 Mar, 2021
Editor invited
On 11 Mar, 2021
This version was not preprinted
Version 1
Posted 31 Dec, 2020
No community comments so far
Editorial decision: Major revision
On 08 Feb, 2021
Review #2 received
Received 29 Jan, 2021
Review #1 received
Received 29 Jan, 2021
Reviewer #2 agreed
On 23 Jan, 2021
Reviewer #1 agreed
On 23 Jan, 2021
Reviewers invited
Invitations sent on 20 Jan, 2021
Editor assigned
On 25 Dec, 2020
Submission checks complete
On 25 Dec, 2020
Editor invited
On 25 Dec, 2020
First submitted
On 20 Dec, 2020
Metrics
Comments: 0
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This preprint is under consideration at The Journal of Headache and Pain. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version (no preprint)
Posted 23 May, 2021
Review #2 received
Received 23 May, 2021
Reviewer #2 agreed
On 16 May, 2021
Review #1 received
Received 16 May, 2021
Reviewers invited
Invitations sent on 11 May, 2021
Reviewer #1 agreed
On 11 May, 2021
Editor assigned
On 10 May, 2021
Submission checks complete
On 10 May, 2021
Editor invited
On 10 May, 2021
Editorial decision: Major revision
On 08 Feb, 2021
First submitted
On 21 Dec, 2020
This version was not preprinted
Version (no preprint)
Posted 23 May, 2021
Review #2 received
Received 23 May, 2021
Reviewer #2 agreed
On 16 May, 2021
Review #1 received
Received 16 May, 2021
Reviews received
Received 12 May, 2021
Reviewers invited
Invitations sent on 11 May, 2021
Reviewer #1 agreed
On 11 May, 2021
Editor assigned
On 11 May, 2021
Submission checks complete
On 10 May, 2021
Editor invited
On 10 May, 2021
First submitted
On 09 May, 2021
Editorial decision: Minor revision
On 08 Feb, 2021
This version was not preprinted
Version (no preprint)
Posted 28 Mar, 2021
Editorial decision: Major revision
On 28 Mar, 2021
Review #2 received
Received 27 Mar, 2021
Review #1 received
Received 19 Mar, 2021
Reviewer #2 agreed
On 15 Mar, 2021
Reviewers invited
Invitations sent on 14 Mar, 2021
Reviewer #1 agreed
On 14 Mar, 2021
Editor assigned
On 11 Mar, 2021
Submission checks complete
On 11 Mar, 2021
Editor invited
On 11 Mar, 2021
This version was not preprinted
Version 1
Posted 31 Dec, 2020
No community comments so far
Editorial decision: Major revision
On 08 Feb, 2021
Review #2 received
Received 29 Jan, 2021
Review #1 received
Received 29 Jan, 2021
Reviewer #2 agreed
On 23 Jan, 2021
Reviewer #1 agreed
On 23 Jan, 2021
Reviewers invited
Invitations sent on 20 Jan, 2021
Editor assigned
On 25 Dec, 2020
Submission checks complete
On 25 Dec, 2020
Editor invited
On 25 Dec, 2020
First submitted
On 20 Dec, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Migraine is a primary headache disorder characterized by recurrent attacks that may have a significant impact on patients’ daily life. Treatment options must often be re-evaluated in light of efficacy, tolerability and compliance issues. Few data on commonly applied treatment algorithms and treatment failures have existed in Germany in 2017/2018. The PANORAMA survey was designed to explore and characterize the migraine healthcare landscape and to demonstrate the medical treatment need at that time in Germany.
Methods: Three different questionnaires were used to assess the profile of the 119 participating centers, characterize migraine patients at centers and evaluate qualitative aspects of the current migraine healthcare situation from a physician´s professional perspective. Data were analyzed as observed and summarized by descriptive statistics.
Results: The results demonstrate that once referred to a migraine specialist, the majority of patients continue to be treated at a specialist. At specialized centers, 41.6% of migraine patients receive prophylactic treatment. 45.4% of prophylactic treatments are initiated with a beta-blocker and 28.1% with an anti-epileptic. Pivotal factors to initiate prophylactic treatment are migraine attack frequency and intensity (58.0%). Treatment decisions are largely based on prior / concomitant diseases and physical constitution of the patient (52.1%). Following an inadequate treatment, most patients either switch substance class or discontinue prophylactic treatment.
Conclusions: PANORAMA gives a comprehensive overview of the migraine healthcare landscape in Germany in 2017/2018, elucidates a lack of common treatment algorithms and reveals a high demand for defined therapy strategies and new prophylactic treatment going forwards.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
This is a list of supplementary files associated with this preprint. Click to download.
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