See the published version of this preprint at BMC Urology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
Research article
Giacomo Rebez
Azienda Sanitaria Universitaria Integrata di Trieste
Corresponding Author
ORCiD: https://orcid.org/0000-0001-7938-1579
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
Non-operative management is established for low-grade (I-III) blunt renal injuries but it is getting increasingly popular even in high grade BRI thanks to angioembolization of active bleedings. To date a systematic review to assess the role of Angioembolization (RAE) in Blunt Renal Injuries (BRI) is not yet present in the literature.
Methods
a literature search was performed, 169 unilateral BRI were included; 124 high grade BRI (92 grade IV and 32 grade V renal injuries, respectively). Most common indication was hemodynamically stable patients with BRI grades II to IV and active contrast extravasation.
Results
Overall, the clinical success rate of RAE was 90% (range 73% − 100%). The rate of re-do embolization was 4.5% gaining a 100% success rate with a second attempt. Some authors reported successful RAE even in patients with grade V BRI, without major abdominal organ injuries and no pelvic fractures. RAE was performed also as adjunctive therapy prior to surgery. Most used agent was micro coils. Nephrectomy rate was 5.8%, mortality rate was 3.2%.
Conclusions
A multidisciplinary approach between interventional radiology and urology should be pursued to make every effort to perform endovascular therapy unless there are multiple visceral injuries or renal pedicle avulsion or expanding retroperitoneal hematoma necessitating surgery.
Keywords
Renal injury, Angioembolization, Trauma, Kidney
Figure 1
This is a list of supplementary files associated with this preprint. Click to download.
Loading...
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Urology.
Version 1
Posted 08 Jan, 2021
No community comments so far
Editorial decision: Major revision
On 01 Feb, 2021
Review #2 received
Received 30 Jan, 2021
Review #1 received
Received 27 Jan, 2021
Review #5 received
Received 15 Jan, 2021
Review #4 received
Received 15 Jan, 2021
Reviewer #4 agreed
On 10 Jan, 2021
Reviewer #5 agreed
On 10 Jan, 2021
Reviewer #3 agreed
On 10 Jan, 2021
Review #3 received
Received 10 Jan, 2021
Reviewer #2 agreed
On 09 Jan, 2021
Reviewer #1 agreed
On 08 Jan, 2021
Editor assigned
On 07 Jan, 2021
Reviewers invited
Invitations sent on 07 Jan, 2021
Submission checks complete
On 05 Jan, 2021
Editor invited
On 04 Jan, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Urology & Nephrology
Learn more about our company.
A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at BMC Urology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Giacomo Rebez
Azienda Sanitaria Universitaria Integrata di Trieste
Corresponding Author
ORCiD: https://orcid.org/0000-0001-7938-1579
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Urology.
Version 1
Posted 08 Jan, 2021
No community comments so far
Editorial decision: Major revision
On 01 Feb, 2021
Review #2 received
Received 30 Jan, 2021
Review #1 received
Received 27 Jan, 2021
Review #5 received
Received 15 Jan, 2021
Review #4 received
Received 15 Jan, 2021
Reviewer #4 agreed
On 10 Jan, 2021
Reviewer #5 agreed
On 10 Jan, 2021
Reviewer #3 agreed
On 10 Jan, 2021
Review #3 received
Received 10 Jan, 2021
Reviewer #2 agreed
On 09 Jan, 2021
Reviewer #1 agreed
On 08 Jan, 2021
Editor assigned
On 07 Jan, 2021
Reviewers invited
Invitations sent on 07 Jan, 2021
Submission checks complete
On 05 Jan, 2021
Editor invited
On 04 Jan, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Urology & Nephrology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Urology.
Background
Non-operative management is established for low-grade (I-III) blunt renal injuries but it is getting increasingly popular even in high grade BRI thanks to angioembolization of active bleedings. To date a systematic review to assess the role of Angioembolization (RAE) in Blunt Renal Injuries (BRI) is not yet present in the literature.
Methods
a literature search was performed, 169 unilateral BRI were included; 124 high grade BRI (92 grade IV and 32 grade V renal injuries, respectively). Most common indication was hemodynamically stable patients with BRI grades II to IV and active contrast extravasation.
Results
Overall, the clinical success rate of RAE was 90% (range 73% − 100%). The rate of re-do embolization was 4.5% gaining a 100% success rate with a second attempt. Some authors reported successful RAE even in patients with grade V BRI, without major abdominal organ injuries and no pelvic fractures. RAE was performed also as adjunctive therapy prior to surgery. Most used agent was micro coils. Nephrectomy rate was 5.8%, mortality rate was 3.2%.
Conclusions
A multidisciplinary approach between interventional radiology and urology should be pursued to make every effort to perform endovascular therapy unless there are multiple visceral injuries or renal pedicle avulsion or expanding retroperitoneal hematoma necessitating surgery.
Figure 1
This is a list of supplementary files associated with this preprint. Click to download.
Loading...