Males/Females, n
|
25/9
|
Age, years, mean±SD
|
50.8±16.3
|
BMI, kg/m², mean±SD
|
29.2±6.3
|
SAPSII, mean±SD
|
38.0±11.8
|
Reason for ICU admission, n
|
Thoracic surgery, n=22
|
Pulmonary endarterectomy n=11
|
|
Lung transplantation, n=7
|
Lobectomy, n=1
|
Tracheal resection, n=1
|
ARDS after lung gunshot wound, n=1
|
Pleural/pulmonary abscess, n=1
|
Heart surgery, n=3
|
Heart transplantation, n=1
|
|
Bentall procedure, n=1
|
Aortic valve replacement, n=1
|
Medical reasons, n=9
|
ARDS due to COVID-19, n=7
|
|
Cardiogenic shock, n=2
|
Type of incisiona, n
|
Sternotomy
|
15
|
Bi-thoracotomy
|
4
|
Clamshell incision
|
3
|
Thoracotomy
|
1
|
Thoracoscopy
|
1
|
Other
|
2
|
Reason for ECMOb
|
|
VV-ECMO (n=25)
|
Hypoxaemia due to ARDS/PGD, n=25
|
VA-ECMO (n=8) or VAV-ECMO (n=1)
|
Cardiogenic shock, n=5
Residual PH, n=4
|
Complications during PPc
|
- Circulatory arrest during an ECMO-VA membrane change
- ECMO pump thrombosis related to HIT
- Cardiac tamponade
- Reperfusion-cannula displacement
- Tracheostomy decannulation
- Sternal wound infection
|
1
1
1
1
1
1
|
PP session characteristicsd
|
Number of PPs before ECMO implantation, median [IQR]
|
0 [0–1]
|
Number of PPs during ECMO, median/patient [IQR]
-all patients
- VV-ECMO
- VA-ECMO
|
2 [1–2.8]
2 [1–3]
2 [1–2]
|
PP session duration, hours, mean±SD
|
18.0±4.2
|
Reason for PP
|
Refractory hypoxaemia n=19
Persistent hypoxaemia n=15
|
Ventilation parameterse
|
Patients with volume-controlled ventilation, n (%)
|
22 (65)
|
Patients with pressure-controlled ventilation, n (%)
|
12 (35)
|
Tidal volume, mL/kg predicted body weight, mean±SD
|
4.5±1.7
|
PEEP, cm H2O, median [IQR]
|
10 [10–15]
|
Respiratory rate, breaths/min, median [IQR]
|
20 [18–28]
|
ECMOf
|
Blood flow, L/min, mean±SD
all patients
VV-ECMO
VA-ECMO
|
4.5±1.7
4.6±1.8
3.7±1.1
|
Gas flow, L/min, mean±SD
all patients
VV-ECMO
VA-ECMO
|
5.6±2.4
6.0±2.4
3.9±1.7
|
FiO2 ECMO, %, mean±SD
all patients
VV-ECMO
VA-ECMO
|
95±12
95±12
95±13
|
Days on ECMO, median [IQR]
all patients
VV-ECMO
VA-ECMO
|
15 [12–24]
15 [12–27]
15 [10–17]
|
Days from last PP to end of ECMO, median [IQR]
all patients
VV-ECMO
VA-ECMO
|
5.5 [3.3–9.5]
5 [3–8]
8.5 [4.8–10.8]
|
Days from ECMO to first PP, median [IQR]
all patients
VV-ECMO
VA-ECMO
|
7 [4–10]
6 [4–10]
7 [4–8]
|
Days from ICU admission to ECMO, median [IQR]
all patients
VV-ECMO
VA-ECMO
|
2 [0–6.8]
3 [0–7]
0 [0–1]
|
Outcome
|
ICU stay (days), median [IQR]
all patients
VV-ECMO
VA-ECMO
|
31.5 [21–49]
32 [26–56]
19 [13–42]
|
Weaning off ECMO within 3 days after last PP, n (%)
all patients
VV-ECMO
VA-ECMO
|
7/34 (21)
6/25 (24)
1/9 (11)
|
Death, n (%)
all patients
VV-ECMO
VA-ECMO
|
9/34 (26)
5/25 (20)
4/9 (44)
|