Are Topical Skin Adhesives an Option for Wound Closure Following Musculoskeletal Oncology Surgery? A STROCSS-compliant Observational Study
Background:
2-octyl cyanoacrylate (2OCA) is a high-viscosity medical-grade tissue adhesive used routinely. However, no studies have evaluated its use in musculoskeletal oncology surgery.
Methods:
We enrolled 99 patients undergoing musculoskeletal oncology surgery. 2OCA was chosen for wound closure, and it was applied by a specific surgeon for all patients. Drying times for the adhesive were recorded, and photographs were obtained intra-operatively. Post-treatment follow-up constituted queries regarding pain level, and recording incisional dehiscence, wound infection, hematoma, and incisional bleeding. Data collection was performed post-operatively at 48 hours, 5–10 days, 14 days, and 30 days. Other adverse events were documented.
Results:
2OCA was applied to 110 incisions in 99 patients constituting 62 female patients and 37 male patients. The mean age of patients was 50.41 (±16.83) years; mean incision length was 10.24 (±5.7) cm; and the mean pain score using a visual analogue scale (VAS) was 2.37 on post-operative day 7. The mean drying time was 1.81 (±0.59) minutes; 91 (91%) patients reported excellent and superior satisfaction, and the remaining patients reported “good” (6%) and “fair” (2%) satisfaction. The percentage of dehiscence, hematoma, and keloid formation was considerably low.
Conclusion:
2OCA was safe in musculoskeletal oncology surgical incisions in this study. The incidence of post-operative adverse events was low. However, some patients developed a hematoma. Post-operative pain was low, and patient satisfaction was high. 2OCA can be a practical alternative to traditional suture closure for skin incisions after musculoskeletal surgery.
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Posted 11 Jan, 2021
Received 16 Jan, 2021
On 08 Jan, 2021
Received 08 Jan, 2021
On 07 Jan, 2021
Invitations sent on 06 Jan, 2021
On 05 Jan, 2021
On 05 Jan, 2021
On 05 Jan, 2021
On 04 Jan, 2021
Are Topical Skin Adhesives an Option for Wound Closure Following Musculoskeletal Oncology Surgery? A STROCSS-compliant Observational Study
Posted 11 Jan, 2021
Received 16 Jan, 2021
On 08 Jan, 2021
Received 08 Jan, 2021
On 07 Jan, 2021
Invitations sent on 06 Jan, 2021
On 05 Jan, 2021
On 05 Jan, 2021
On 05 Jan, 2021
On 04 Jan, 2021
Background:
2-octyl cyanoacrylate (2OCA) is a high-viscosity medical-grade tissue adhesive used routinely. However, no studies have evaluated its use in musculoskeletal oncology surgery.
Methods:
We enrolled 99 patients undergoing musculoskeletal oncology surgery. 2OCA was chosen for wound closure, and it was applied by a specific surgeon for all patients. Drying times for the adhesive were recorded, and photographs were obtained intra-operatively. Post-treatment follow-up constituted queries regarding pain level, and recording incisional dehiscence, wound infection, hematoma, and incisional bleeding. Data collection was performed post-operatively at 48 hours, 5–10 days, 14 days, and 30 days. Other adverse events were documented.
Results:
2OCA was applied to 110 incisions in 99 patients constituting 62 female patients and 37 male patients. The mean age of patients was 50.41 (±16.83) years; mean incision length was 10.24 (±5.7) cm; and the mean pain score using a visual analogue scale (VAS) was 2.37 on post-operative day 7. The mean drying time was 1.81 (±0.59) minutes; 91 (91%) patients reported excellent and superior satisfaction, and the remaining patients reported “good” (6%) and “fair” (2%) satisfaction. The percentage of dehiscence, hematoma, and keloid formation was considerably low.
Conclusion:
2OCA was safe in musculoskeletal oncology surgical incisions in this study. The incidence of post-operative adverse events was low. However, some patients developed a hematoma. Post-operative pain was low, and patient satisfaction was high. 2OCA can be a practical alternative to traditional suture closure for skin incisions after musculoskeletal surgery.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5