See the published version of this preprint at Orphanet Journal of Rare Diseases.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Klane White
Seattle Children's Hospital
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Disorders of the spine present a common and difficult management concern in patients with skeletal dysplasia. Due to the rarity of these conditions however, the literature, largely consisting of small, single institution case series, is sparse in regard to well-designed studies to support clinical decision making in these situations.
Methods: Using the Delphi method, an international, multi-disciplinary group of individuals, with significant experience in the care of patients with skeletal dysplasia, convened to develop multi-disciplinary, “best practice” guidelines in the care of spinal disorders in patients with skeletal dysplasia.
Results: Starting with 33 statements, the group a developed a list of 31 “best practice” guidelines.
Conclusions: The guidelines are presented and discussed to provide context for clinicians in their decision making in this often-challenging realm of care.
Keywords
Skeletal dysplasia; Spine; Scoliosis; Kyphosis; Cervical instability; Spinal cord compression; Myelopathy.
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Peer Review Timeline
CURRENT STATUS: Published
View the published article at Orphanet Journal of Rare Diseases.
Version 2
Posted 20 May, 2020
No community comments so far
Editorial decision: Accept
On 17 May, 2020
Editor assigned
On 10 May, 2020
Submission checks complete
On 09 May, 2020
Editor invited
On 09 May, 2020
No comments provided
Editorial decision: Major revision
On 06 Apr, 2020
Review #2 received
Received 02 Apr, 2020
Review #1 received
Received 29 Mar, 2020
Reviewer #1 agreed
On 13 Mar, 2020
Reviewer #2 agreed
On 13 Mar, 2020
Reviewers invited
Invitations sent on 04 Mar, 2020
Editor assigned
On 17 Feb, 2020
Submission checks complete
On 16 Feb, 2020
Editor invited
On 16 Feb, 2020
First submitted
On 15 Feb, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Internal Medicine
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See the published version of this preprint at Orphanet Journal of Rare Diseases.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Klane White
Seattle Children's Hospital
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Orphanet Journal of Rare Diseases.
Version 2
Posted 20 May, 2020
No community comments so far
Editorial decision: Accept
On 17 May, 2020
Editor assigned
On 10 May, 2020
Submission checks complete
On 09 May, 2020
Editor invited
On 09 May, 2020
No comments provided
Editorial decision: Major revision
On 06 Apr, 2020
Review #2 received
Received 02 Apr, 2020
Review #1 received
Received 29 Mar, 2020
Reviewer #1 agreed
On 13 Mar, 2020
Reviewer #2 agreed
On 13 Mar, 2020
Reviewers invited
Invitations sent on 04 Mar, 2020
Editor assigned
On 17 Feb, 2020
Submission checks complete
On 16 Feb, 2020
Editor invited
On 16 Feb, 2020
First submitted
On 15 Feb, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Internal Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Orphanet Journal of Rare Diseases.
Background: Disorders of the spine present a common and difficult management concern in patients with skeletal dysplasia. Due to the rarity of these conditions however, the literature, largely consisting of small, single institution case series, is sparse in regard to well-designed studies to support clinical decision making in these situations.
Methods: Using the Delphi method, an international, multi-disciplinary group of individuals, with significant experience in the care of patients with skeletal dysplasia, convened to develop multi-disciplinary, “best practice” guidelines in the care of spinal disorders in patients with skeletal dysplasia.
Results: Starting with 33 statements, the group a developed a list of 31 “best practice” guidelines.
Conclusions: The guidelines are presented and discussed to provide context for clinicians in their decision making in this often-challenging realm of care.
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