Empty Nest Syndrome (ENS) is not a listed clinical entity in DSM-5, although ICD-11 has listed it under “Other Associated Problems with Social or Cultural Environment”. However, a complex grief state is observed in the parents when their children leave home for study and work or marriage. Literature shows ENS may progress to clinical-grade depression and anxiety, if left uncared.
The study presents a solution (LENS) to assess such risks in ENS using Cardiovascular Optical Biomarkers (COB) from the capillary blood flow signal of the index finger using the technique of arterial photoplethysmography when the finger is gently pressed on the phone camera with the torchlight ‘on’. The scores of COB provide the psychological and metabolic snapshots of the mind-body homeostasis.
The study observes that (a) COB (e.g., SD1/SD2, LF/HF, HRVScore, and ENERGY), obtained through Lyfas tests, and (b) physical e.g., Diastolic Blood Pressure, BMI, Heart rate, HbA1c, TSH, and Estradiol have significant roles in the backdrop of ENS. Bland Altman's reliability measure shows that LENS (novel instrument under trial) has a high agreement of 92.85% and 93.86%, respectively with ENS scoring done by senior psychologists (champion instrument – 1) and HAM-D grading performed by psychiatrists (champion instrument – 2).
LENS can be used as an assistive tool to screen and monitor ENS cases in a health set up.