Lake Taihu is an important drinking water source for cities in the Yangtze River Delta region, while the dramatic fluctuation in turbidity has caused serve problems for local waterworks management. Because the sediment behavior induced by wind disturbance was believed to be the main factor for the matter, the effect of wind fields on the hydrodynamics and sediment distribution of Lake Taihu and the turbidity of the raw water were conducted based on a wind-driven numerical model. The obtained results indicate that wind direction was more influential on the structure of flow and wave fields, while wind speed contributed more to the field intensity, and the suspended sediment of the water intake area primarily consisted of migrated particles from other erosion regions. The high consistency between the simulated suspended sediment concentration and the turbidity with a lag effect of 7 h made it possible for turbidity prediction when combined with the weather forecast technique. The model achieved operation adjustment in advance, thus improving the management efficiency of the waterworks.