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Methodologies
Characterization and Eradication of The High Concentration Infection Source of Oral Segment of Candida By Infection Examination Diagnosis System
Yuusuke Nonomura
Nonomura Dental Clinic
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
The most recent version of this article is available here.
Purpose: Candida albicans (CA) is a major pathogenic fungus that causes a critical infection and life-threatening disease. During ventilator usage for the treatment of COVID-19-associated pneumonia, CA colonization of the airway should be prevented to avoid an increase in mortality. Our aim was to characterize and analyze the infection of Candida albicans (CA) for eradication.
Methods: We characterized and analyzed the infection source and infection field which are carrier field, diffusion field, and spread field, by using a new infection examination (diagnostic) system (IEDS) comprising a new dental formula (measurement analysis) medium (DFM) with time, space, and phase, and the simultaneous relative differential equations (C4RDE).
Results: This study showed that CA was not an endogenous microorganism, but a fungus that infected teeth causing dental caries that was successfully eradicated from all teeth of 353 Japanese patients (oral cavity segment). [In the first examination, the percentages of people with CA (+) was 40.5% (the DMFT: 62.8%) and CA(-) was 56.4% (the DMFT: 47.1%). The difference in DMFT was 15.7% (P<0.01)] (DMFT is decayed, missing, and filled tooth index).
Conclusion: Our methods help to eradicate the infection source (IS), prevent critical infection, and reduce mortality. The IEDS is a powerful tool that can be applied for any microbial infection easily. It is possible for the dentists to characterize CA by IEDS and eradicate CA from the oral cavity.
Keywords
Candida albicans, IEDS, ventilator, tooth caries
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Methodologies
Characterization and Eradication of The High Concentration Infection Source of Oral Segment of Candida By Infection Examination Diagnosis System
Yuusuke Nonomura
Nonomura Dental Clinic
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
No community comments so far
Version 1
Posted 21 Jan, 2021
No comments provided
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
The most recent version of this article is available here.
Purpose: Candida albicans (CA) is a major pathogenic fungus that causes a critical infection and life-threatening disease. During ventilator usage for the treatment of COVID-19-associated pneumonia, CA colonization of the airway should be prevented to avoid an increase in mortality. Our aim was to characterize and analyze the infection of Candida albicans (CA) for eradication.
Methods: We characterized and analyzed the infection source and infection field which are carrier field, diffusion field, and spread field, by using a new infection examination (diagnostic) system (IEDS) comprising a new dental formula (measurement analysis) medium (DFM) with time, space, and phase, and the simultaneous relative differential equations (C4RDE).
Results: This study showed that CA was not an endogenous microorganism, but a fungus that infected teeth causing dental caries that was successfully eradicated from all teeth of 353 Japanese patients (oral cavity segment). [In the first examination, the percentages of people with CA (+) was 40.5% (the DMFT: 62.8%) and CA(-) was 56.4% (the DMFT: 47.1%). The difference in DMFT was 15.7% (P<0.01)] (DMFT is decayed, missing, and filled tooth index).
Conclusion: Our methods help to eradicate the infection source (IS), prevent critical infection, and reduce mortality. The IEDS is a powerful tool that can be applied for any microbial infection easily. It is possible for the dentists to characterize CA by IEDS and eradicate CA from the oral cavity.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Due to technical limitations, full-text HTML conversion of this manuscript could not be completed. However, the manuscript can be downloaded and accessed as a PDF.
Due to technical limitations, table 1 to 10 is only available as a download in the Supplemental Files section.