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Research Article
Ali Ahmadi
Department of Epidemiology and Biostatistics, School of Health and Modeling in Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
Background: Chronic obstructive pulmonary disease (COPD) is a chronic and complex respiratory disorder that is associated with the airflow limitation and increased inflammatory response of the lungs to harmful particles and gases. The purpose of this original study was to describe the profile of Shahrekord PERSIAN Cohort Study regarding COPD in southwestern Iran.
Methods: This study of asthma and respiratory diseases is a subcohort of the larger cohort study, i.e., Shahrekord PERSIAN cohort, a population-based prospective study on people aged 35-70 years in southwestern Iran (n=10,075). The sample size of the subcohort was 8500 people. Annual follow-ups (person-year) of the cohort were designed to be conducted up to 2036. The instruments to collect data on various exposures were derived from the questionnaires previously developed in extensive multinational studies (occupational exposures, smoking, housing status, and fuel consumption, history of respiratory and chronic diseases, comorbidity, etc.). The Global Initiative for Chronic Obstructive Lung Disease (GOLD) and the lower limit of normal (NLL) spirometric criteria were used to confirm COPD diagnosis.
Results: The response rate was 93.85%. The mean age of the participants was 49.48 ± 9.32; 47.9% were male and 52.9% were female; about 20% were in rural areas and nearly 16% of the population was current smokers; the fuel used by most of the participants for heating the house and cooking was gas. The most common comorbidity among participants was dyslipidemia; 30% of people have three or more comorbidities. According to GOLD and LLN criteria, 3.6% and 8.4% of participants had COPD, respectively. 4.3% of the participants had a history of chronic lung disease. The mean FEV1/ FVC was 92.48 (SD, 7.47), the mean FEF 25-75 was 3.43 (SD, 1.28) L. 47.6% had a history of chronic phlegm; 2.7% of the participants had shortness of breath and wheezing
Conclusion: Epidemiological research is necessary to create an appropriate framework to fight COPD. This framework requires a better description of men and women at risk of developing COPD and describing people with early-stage illnesses.
Keywords
Profile, Chronic Obstructive, Pulmonary Disease, Longitudinal, Cohort study, Iran
Figure 1
No competing interests reported.
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View the published article at BMC Pulmonary Medicine.
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On 19 Feb, 2021
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Received 03 Feb, 2021
Reviewers agreed
On 24 Jan, 2021
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On 24 Jan, 2021
Editor invited
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Subject Areas
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A new preprint design is coming!
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See the published version of this preprint at BMC Pulmonary Medicine.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Ali Ahmadi
Department of Epidemiology and Biostatistics, School of Health and Modeling in Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Pulmonary Medicine.
Version 1
Posted 28 Jan, 2021
No community comments so far
Editorial decision: Major revision
On 19 Feb, 2021
Reviews received
Received 03 Feb, 2021
Reviewers agreed
On 24 Jan, 2021
Reviewers invited
Invitations sent on 24 Jan, 2021
Editor assigned
On 24 Jan, 2021
Editor invited
On 22 Jan, 2021
Submission checks complete
On 22 Jan, 2021
First submitted
On 21 Jan, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Pulmonology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Pulmonary Medicine.
Background: Chronic obstructive pulmonary disease (COPD) is a chronic and complex respiratory disorder that is associated with the airflow limitation and increased inflammatory response of the lungs to harmful particles and gases. The purpose of this original study was to describe the profile of Shahrekord PERSIAN Cohort Study regarding COPD in southwestern Iran.
Methods: This study of asthma and respiratory diseases is a subcohort of the larger cohort study, i.e., Shahrekord PERSIAN cohort, a population-based prospective study on people aged 35-70 years in southwestern Iran (n=10,075). The sample size of the subcohort was 8500 people. Annual follow-ups (person-year) of the cohort were designed to be conducted up to 2036. The instruments to collect data on various exposures were derived from the questionnaires previously developed in extensive multinational studies (occupational exposures, smoking, housing status, and fuel consumption, history of respiratory and chronic diseases, comorbidity, etc.). The Global Initiative for Chronic Obstructive Lung Disease (GOLD) and the lower limit of normal (NLL) spirometric criteria were used to confirm COPD diagnosis.
Results: The response rate was 93.85%. The mean age of the participants was 49.48 ± 9.32; 47.9% were male and 52.9% were female; about 20% were in rural areas and nearly 16% of the population was current smokers; the fuel used by most of the participants for heating the house and cooking was gas. The most common comorbidity among participants was dyslipidemia; 30% of people have three or more comorbidities. According to GOLD and LLN criteria, 3.6% and 8.4% of participants had COPD, respectively. 4.3% of the participants had a history of chronic lung disease. The mean FEV1/ FVC was 92.48 (SD, 7.47), the mean FEF 25-75 was 3.43 (SD, 1.28) L. 47.6% had a history of chronic phlegm; 2.7% of the participants had shortness of breath and wheezing
Conclusion: Epidemiological research is necessary to create an appropriate framework to fight COPD. This framework requires a better description of men and women at risk of developing COPD and describing people with early-stage illnesses.
Figure 1
No competing interests reported.
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