Synthesis and Characterization of Zinc oxide Nanoparticles for Antifungal And Antibacterial Activity.

doi:10.21203/rs.3.rs-1538022/v1

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Research Article

Synthesis and Characterization of Zinc oxide Nanoparticles for Antifungal And Antibacterial Activity.

https://doi.org/10.21203/rs.3.rs-1538022/v1

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Zinc Oxide Nano particles promise an important role in various industries like pharma, fertilizer, textiles and garments due to their specific properties such as anti-fungal, antibacterial and anti-rust. Zinc oxide nanoparticles were prepared by eco-friendly wet chemical method. Formation of ZnO nanoparticles was confirmed by using spectroscopic and microscopic investigations. Samples were characterized using Ultra-Violet Spectroscopy, Fourier Transform Infrared, Scanning Electron Microscopy, Transmission Electron microscope, X-ray Diffraction, four probe Voltage-Current characterizations and Antifungal and antimicrobial activity

Zinc Oxide Nanoparticles (ZnO NPs)

Antibacterial activity

Antifungal Activity

XRD

FTIR

SEM

TEM

VI. Bacillus Subtilis

Pseudomonas aeruginosa

Candida

A.niger

Due to their special characters metal oxide nanoparticles are utilized in different capacity as pharma for making special targeting drugs, in Agriculture industry for fertilizer and environmental friendly pesticides. In paint industries, these are useful in Nano-electronics component. Metal oxide nano particles are used for making biomedical Nano-devices. Metal oxides nanoparticles are reported to show very crucial features in many areas of physics, chemistry and material Nano science (1).

Zinc oxide nanoparticles are very important class of metal oxide nanoparticles. It is environmental friendly and has various set of applications .It has diverse properties depending upon its morphology (2). It is widely used in pharm industry, fabrication of Nano electronics devise, paint industries ,garments and textiles industries and has various biomedical application .

We have synthesized and characterized zinc oxide nanoparticles (ZnO NP) and observed various biological effects on different type of microorganism. Zinc Oxide Nano particles have reported to have anti-fungal, anti-bacterial property which gives wide application in drugs and food processing industries. Zinc oxide Nano particles is used in area of antibacterial and photo catalysis (3).Zinc Oxide nanoparticles have shown antimicrobials agents against pathogenic and spoilage microorganism (4). Metal oxide nanoparticles provide an area this is certainly big in terms of their unique optical, magnetic, catalytic and electrical properties [5]. It is widely used being as a food products preservative because of the anti-microbial prospective. ZnO has also been utilized in the packaging of meals cans such meat, corn, fish and peas to prevent spoilage and preserve the colour [6].

Different techniques have been used to prepare zinc oxide nanoparticles such as hydrothermal[9–12], solvo thermal [13,14], micro emulsion [15], sol-gel [16,17] and thermal decomposition of precursors [18,19]. Using wet chemical method of synthesis, in accordance with Raghupathi et al. and Applerot et al., ZnO nanoparticles exhibit maximum degree of antibacterial activity with the reduce in average particle size[20,21]. Method of synthesis of nanoparticles strongly affects the design and size of nanoparticles, which determines the properties of nanoparticles [22,23].

ZnO nanoparticles were synthesized utilizing by wet chemical method by the use of Zinc nitrate. The nanoparticles were analyzed. Anti-bacterial activity has been discovered to work on Fungus and bacteria. The nanoparticles were analyzed UV, TEM, FTIR, SEM and XRD and four probes. The utmost consumption is at 380 nm in Ultraviolet evaluation. FTIR of Zinc Oxide Nanoparticles showed different peaks of useful group as Alcohol / Phenol O-H Stretch, Alkyl C-H Stretch, Aliphatic Esters, Alkenes. The SEM and TEM analysis revealed particles morphology and measurements of zinc oxide nanoparticles. The XRD analyses showed crystalline structure and particle size of ZnO NPs. The resistivity of synthesis sample of ZnO-NPs ended up being come 17.88x10⁹. The biological activity of ZnO NPs revealed its Anti-bacterial and resistive property for the fungus.

Ethics approval and consent to participate: Not Applicable

Consent for publication:

I Sumit Yadav give my consent for information about myself to be published in the Journal of Nanobiotechnology. I understand that the information will be published without my name attached, but that full anonymity cannot be guaranteed. I understand that the text and any pictures or videos published in the article will be freely available on the internet and may be seen by the general public. The pictures, videos and text may also appear on other websites or in print, may be translated into other languages or used for commercial purposes. I have been offered the opportunity to read the manuscript.

Availability of data and materials: The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.

Competing interests: Not applicable

Funding: No Funding

Authors' contributions - provide individual author contribution:

Sumit Yadav has done the presented research work, wrote the main manuscript text and prepared figures. Veenu Sisodia guided the research work. All authors reviewed the manuscript.

Acknowledgements: Physics lab, Jayoti Vidyapeeth Women’s University, Jaipur; Department of Physics, Central University of Rajasthan, BandarSindri and Materials Science Department, Malviya National Institute of Technology, Jaipur

Authors' information (optional)

Sumit Yadav, Physics lab, Jayoti Vidyapeeth Women’s University, Jaipur, India

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No competing interests reported.

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Synthesis and Characterization of Zinc oxide Nanoparticles for Antifungal And Antibacterial Activity.

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