1. Meschia JF, Bushnell C, Boden-Albala B, Braun LT, Bravata DM, et al. Guidelines for the primary prevention of stroke: A statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2014; 45:3754-3832.
2. Gupta A, Baradaran H, Al-Dasuqi K, Knight-Greenfield A, Giambrone AE, Delgado D, et al. Gadolinium Enhancement in Intracranial Atherosclerotic Plaque and Ischemic Stroke: A systematic review and Meta‐Analysis. J Am Heart Assoc 2016;5:e003816.
3. Michel JB, Virmani R, Arbustini E, Pasterkamp G. Intraplaque haemorrhages as the trigger of plaque vulnerability. Eur Heart J 2011;32:1977-1985.
4. Janssen H, Wagner CS, Demmer P, Callies S, Sölter G, Loghmani-khouzani H, et al. Acute perioperative-stress-induced increase of atherosclerotic plaque volume and vulnerability to rupture in apolipoprotein-E-deficient mice is amenable to statin treatment and IL-6 inhibition. Dis Model Mech 2015;8: 1071–1080.
5. Scheiermann C, Frenette PS, Hidalgo A. Regulation of leucocyte homeostasis in the circulation. Cardiovasc Res 2015;107:340-351.
6. Huang R, Abdelmoneim SS, Ball CA, Nhola LF, Farrell AM, Feinstein S, et al. Detection of carotid atherosclerotic plaque neovascularization using contrast enhanced ultrasound: A systematic review and Meta-Analysis of diagnostic accuracy studies. J Am Soc Echocardiogr 2016; 29: 491-502.
7. Schmidt C, Fischer T, Rückert RI, Oberwahrenbrock T, Harms L, Kronenberg G, et al. Identification of neovascularization by contrast–enhanced ultrasound to detect unstable carotid stenosis. PLoS One 2017; 12:e0175331.
8. Legein B, Temmerman L, Biessen EA, Lutgens E. Inflammation and immune system interactions in atherosclerosis. Cell Mol Life Sci 2013; 20:3847-3869.
9. Liesz A, Hu X, Kleinschnitz C, Offner H.The functional role of regulatory lymphocytes in stroke: facts and controversies. Stroke 2015; 46:1422–1430.
10. World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications. Report of a WHO consultation. Geneva: WHO Department of Non communicable Disease Surveillance. 1999.
11. Li Z, Du L, Wang F, Luo X. Assessment of the arterial stiffness in patients with acute ischemic stroke using longitudinal elasticity modulus measurements obtained with Shear Wave Elastography. Med Ultrason 2016; 18:182-189.
12. Li ZJ, Liu Y, Du LF, Luo XH. Evaluating arterial stiffness in type 2 diabetes patients using ultrasonic radiofrequency. J Huazhong Univ Sci Technolog Med Sci 2016; 36:442-448.
13. Kim SA, Park SH, Jo SH, Park KH, Kim HS, Han SJ, et al. Alterations of carotid arterial mechanics preceding the wall thickening in patients with hypertension. Atherosclerosis 2016; 248: 84-90.
14. Nandalur KR, Hardie AD, Raghavan P, Schipper MJ, Baskurt E, Kramer CM. Composition of the stable carotid plaque: insights from a multidetector computed tomography study of plaque volume. Stroke 2007; 38:935-940.
15. Alsulaimani S, Gardener H, Elkind MS, Cheung K, Sacco RL, Rundek T. Elevated homocysteine and carotid plaque area and densitometry in the Northern Manhattan study. Stroke 2013; 44:457-461.
16. Howard DP, van Lammeren GW, Rothwell PM, Redgrave JN, Moll FL, de Vries JP, et al. Symptomatic carotid atherosclerotic disease: correlations between plaque composition and ipsilateral stroke risk. Stroke 2015; 46:182–189.
17. Stefanadis C, Antoniou CK, Tsiachris D, Pietri P. Coronary atherosclerotic vulnerable plaque: current perspectives. J Am Heart Assoc 2017; 6: e005543.
18. Steinl DC, Kaufmann BA. Ultrasound imaging for risk assessment in atherosclerosis. Int J Mol Sci 2015; 16:9749–9969.
19. Rafailidis V, Pitoulias G, Kouskouras K, Rafailidis D. Contrast-enhanced ultrasonography of the carotids. Ultrasonography 2015; 34:312–323.
20. Moguillansky D, Leng X, Carson A, Lavery L, Schwartz A, Chen X, et al. Quantification of plaque neovascularization using contrast ultrasound: a histologic validation. Eur Heart J 2011; 32: 646–653.
21. Osborn EA, Jaffer FA. Imaging inflammation and neovascularization in atherosclerosis: clinical and translational molecular and structural imaging targets. Curr Opin Cardiol 2015; 30: 671–680.
22. Sluimer JC, Gasc JM, van Wanroij JL, Kisters N, Groeneweg M, Sollewijn Gelpke MD, et al. Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis. J Am Coll Cardiol 2008; 51:1258–1265.
23. Raz L, Knoefel J, Bhaskar K. The neuropathology and cerebrovascular mechanisms of dementia. J Cereb Blood Flow Metab 2016; 36:172–186.
24. Hosseini AA, Kandiyil N, Macsweeney ST, Altaf N, Auer DP. Carotid plaque hemorrhage on magnetic resonance imaging strongly predicts recurrent ischemia and stroke. Ann Neurol 2013; 73: 774– 784.
25. Teng Z, Sadat U, Brown AJ, Gillard JH. Plaque hemorrhage in carotid artery disease: Pathogenesis, clinical and biomechanical considerations. J Biomech 2014; 47:847–858.
26. You X, Huang P, Zhang C, Wang M, Zhang Y, Hong Y, et al. Relationship between enhanced intensity of contrast enhanced ultrasound and microvessel density of aortic atherosclerostic plaque in rabbit model. PLoS One 2014; 9: e92445.
27. Li J, Flammer AJ, Reriani MK, Matsuo Y, Gulati R, Friedman PA, et al. High leukocyte count is associated with peripheral vascular dysfunction in individuals with low cardiovascular risk,” Circ J 2013; 780–785.
28. Langheinrich AC, Kampschulte M, Scheiter F, Dierkes C, Stieger P, Bohle RM, et al. Atherosclerosis, inflammation and lipoprotein glomerulopathy in kidneys of apoE−/−/LDL−/− double knockout mice. BMC Nephrol 2010; 11: 18.
29. Li G, Chen SJ, Oparil S, Chen YF, Thompson JA. Direct in vivo evidence demonstrating neointimal migration of adventitial fibroblasts after balloon injury of rat carotid arteries,” Circulation 2000;101:1362–1365.
30. Virmani R, Kolodgie FD, Burke AP, Finn AV, Gold HK, Tulenko TN, et al. Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage. Arterioscler Thromb Vasc Biol 2005; 25:2054–2061.
31. Xu J, Lu X, Shi GP. Vasa Vasorum in Atherosclerosis and Clinical Significance. Int J Mol Sci 2015; 16:11574–11608.
32. Mikhed Y, Daiber A, Steven S. Mitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular Dysfunction. Int J Mol Sci 2015; 16:15918–15953.
33. Maiellaro K, Taylor WR. The Role of the Adventitia in Vascular Inflammation. Cardiovasc Res 2007; 75:640–648.