As shown in table 1, there are 67 patients, 31 males and 36 females, with an age range of 5-72 years (median age, 44 years). Most of the patients infected with SARS-CoV-2 have lesions in the chest CT images (n=54). Common symptoms at onset of illness were fever (n=58), cough (n=52), and sputum production (n=35). Less common symptoms were chest tightness (n=12), Sore throat (n=8), diarrhea(n=5), dizziness (n=3), shortness of breath (n=4), nausea and vomiting (n=2), myalgia or fatigue (n=3), and headache (n=2). For the job type, 59 patients are self-employed, 4 patients are farmers, and 4 patients are company employees. For the type of infection source, 34 patients lived in Wuhan, 3 patients lived in Hubei province, 27 patients had a history of contact with COVID-19 patients, 2 patients had a history of contact with suspected patients, and only one patient had no histories of contact with COVID-19 patients or suspected patients. For the smoking status, two of sixty-seven patients were former smokers, three patients were current smokers, and the remaining sixty-two patients were non-smokers. There are sixteen patients with one or more of the following comorbidities: hypertension (n=11), diabetes (n=7), cancer (n=1), respiratory disease (n=1), cardiovascular disease (n=1), and connective tissue disease (n=1). After the treatment, 44 patients were cured, and the remaining23 patients were still hospitalized.
Table 1.Demographic and clinical characteristics of 67 patients with SARS-CoV-2
|
Number
|
Gender (male)
|
31 (46.3%)
|
Positive CT findings
|
56 (83.6%)
|
Age
|
44 (5~72)
|
Job type
|
4 (6.0%) farmers, 59 (88.0%) self-employed,
4 (6.0%) company employees
|
Infection source type
|
34 (50.8%) lived in Wuhan,
3 (4.4%) lived in Hubei Province,
27 (40.3%) got contact with patients,
2 (3.0%) got contact with suspected patient,
1 (1.5%) unknown
|
Smoking status
|
62 (92.5%) are non-smokers, 2 (3.0%) are former smokers, 3 (4.5%) are current smokers
|
Severe patients
|
3 (4.5%)
|
Fever
|
58 (86.6%)
|
Cough
|
52 (77.6%)
|
Sputum production
|
35 (52.2%)
|
Chest tightness
|
12 (17.9%)
|
Sore throat
|
8 (11.9%)
|
Diarrhoea
|
5 (7.5%)
|
Dizziness
|
3 (4.5%)
|
Shortness of breath
|
4 (6.0%)
|
Nausea and vomiting
|
2 (3.0%)
|
Myalgia or fatigue
|
3 (4.5%)
|
Headache
|
2 (3.0%)
|
Current status
(cured/hospitalized)
|
44 (65.7%) cured,
23 (34.3%) hospitalized
|
All the patients underwent CT 1–11 days after admission (median, 4 days).There were 54 of 67 patients with lesions, and the remaining 13 patients were normal in chest CT images. As shown in table 2, fifty of the fifty-four patients had lesions in the peripheral regions (Figure 1), and four patients had lesions in the central regions. Twelve patients had abnormalities in the middle upper lobe, and the remaining forty-two patients had abnormalities in the middle lower lobe. There were 8 patients with single lesion (Figure 2(a)) and 46 patients with multiple lesions (Figure 1). Forty-two of the fifty-four patients had ground-glass opacities (Figure 1-4) and twelve patients had isolated consolidation (Figure 2(a)). Interlobular septal thickening was identified in eleven patients. Reversed halo sign was noted in nine patients. There were eighteen patients with air bronchogram. Three patients had bronchial wall thickening. Tree-in-bud pattern was identified in one patient (Figure 5(a)). Air cavities were present in four patients (Figure 3). Pleural thickening or pleural effusion was noted in fourteen patients. Only two patients had intrathoracic lymph node enlargement (Figure 4 (d)).
Table 2. CT features in sixty-seven patients with SARS-CoV-2
|
Number
|
Peripheral/central lesions
|
50 (92.6%) peripheral; 4(7.4%) central
|
Lesions in middle upper/lower lobes
|
12 (22.2%) upper lobe; 42 (77.8%) lower lobe
|
Single/multiple lesions
|
8 (14.8%) single; 46 (85.2%) multiple
|
Ground-glass opacities
|
42 (77.8%)
|
Consolidation
|
12 (22.2%)
|
Interlobular septal thickening
|
11 (20.4%)
|
Reversed halo sign
|
9 (16.7%)
|
Air bronchogram
|
18 (33.3%)
|
Bronchial wall thickening
|
3 (5.6%)
|
Tree-in-bud pattern
|
1 (1.9%)
|
Air cavity
|
4 (7.4%)
|
Pleural thickening or pleural effusion
|
14 (25.9%)
|
Intrathoracic lymph node enlargement
|
2 (3.7%)
|