1. Comparison of the incidence of lower limb venous thrombosis after different replacement types
Among the 216 patients, 35 had total hip arthroplasty, 8 had deep venous thrombosis after operation, the incidence of thrombosis was 22.9%; 74 had hemi-hip arthroplasty, and 34 had deep venous thrombosis after the operation, and the incidence of thrombosis 46.6%; 77 cases of total knee arthroplasty, 25 cases of postoperative deep venous thrombosis of the lower extremities, the incidence of thrombosis was 32.5%; 31 cases of unicondyle replacement, 19 cases of postoperative deep venous thrombosis of the lower extremities, and the incidence of thrombosis 61.3%; See Table 1.
2. Based on age, gender and replacement type as the standard, using the PSM propensity score matching method, 86 patients were selected as the control group from 130 patients without deep vein thrombosis after operation, and the general information of 172 patients; see Table 2.
3. Comparison of the levels of D-dimer, albumin and hemoglobin between the thrombus group and the control group
The D-dimer level of patients in the thrombus group was 0.98 (0.378 ~ 3.463) mg/L, which was higher than the control group by 0.43 (0.238 ~ 0.893) mg/L, P = 0.000, the difference was statistically significant; the albumin of the patients in the thrombosis group was (38.806 ± 4.625) g/L, lower than the control group (41.003 ± 3.824) g/L, P = 0.001, the difference was statistically significant; the hemoglobin of the thrombosis group was (128.663 ± 15.776) g/L, lower than the control group (134.430 ± 12.842) g/L, P = 0.009, the difference is statistically significant; see Table 3.
Comparison of D-mer, albumin and hemoglobin levels in hip and knee replacement patients in thrombosis group
The D-dimer level of hip replacement patients was 3.25 (1.240 ~ 8.350) mg/L, which was higher than the D-dimer level of knee replacement patients by 0.45 (0.290 ~ 0.970) mg/L, P = 0.000, the difference was statistically significant Scientific significance; the albumin level of hip replacement patients was (36.199 ± 4.569) g/L, which was lower than that of knee replacement patients (40.969 ± 3.4269) g/L, P = 0.000, the difference was statistically significant; hip joint The hemoglobin level of replacement patients was (125.897 ± 16.665) g/L, which was lower than that of knee replacement patients (130.957 ± 14.785) g/L, P = 0.140, the difference was not statistically significant; see Table 4.
The diagnostic efficacy of D-dimer, prothrombin time, ESR, CRP, and age on the formation of DVT in lower limbs after hip replacement
ROC curve analysis results show that the best cut-off value of D-dimer in the diagnosis of lower extremity DVT after hip replacement is 1.745 mg/L, sensitivity is 71.8%, specificity is 74.1%, and area under the curve is 0.746 (95%). CI: 0.622 ~ 0.870), P = 0.001, which is statistically significant; the best cutoff value of prothrombin time is 10.850s, the sensitivity is 66.7%, the specificity is 66.7%, and the area under the curve is 0.683 (95%CI: 0.551 ~ 0.816), P = 0.012, which is statistically significant; the best ESR cutoff value is 15.500mm/h, the sensitivity is 61.5%, the specificity is 70.4%, and the area under the curve is 0.658 (95%CI: 0.526 ~ 0.790), P = 0.030, statistically significant; the best cut-off value of CRP is 2.375 mg/L, sensitivity is 94.9%, specificity is 33.3%, area under the curve is 0.651 (95%CI: 0.514 ~ 0.787), P = 0.039, It is statistically significant; the best cut-off value for age is 72, the sensitivity is 71.8%, the specificity is 100%, the area under the curve is 0.869 (95%CI: 0.778 ~ 0.960), P = 0.000, which is statistically significant; see Fig. 1.
The diagnostic efficacy of D-dimer, prothrombin time, ESR, CRP, and age on the formation of lower limb DVT after knee arthroplasty
ROC curve analysis results show that the best cut-off value of D-dimer in the diagnosis of lower limb DVT after knee arthroplasty is 0.850 mg/L, sensitivity is 78.7%, specificity is 44.1%, and area under the curve is 0.622 (95% CI: 0.515 ~ 0.729), P = 0.032, statistically significant; the best cut-off value for age is 70.5 years, sensitivity is 34.0%, specificity is 86.4%, area under the curve is 0.589 (95%CI: 0.476 ~ 0.703), P = 0.115, no statistical significance; see Fig. 2.