[1] Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)[J]. Jama, 2016, 315(8): 801-810.
[2] Annane D, Bellissant E, Cavaillon JM. Septic shock[J]. Lancet, 2005, 365(9453): 63-78.
[3] Haak BW, Wiersinga WJ. The role of the gut microbiota in sepsis[J]. Lancet Gastroenterol Hepatol, 2017, 2(2): 135-143.
[4] Vincent JL, Marshall JC, Namendys-Silva SA, et al. Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit[J]. Lancet Respir Med, 2014, 2(5): 380-386.
[5] Kwon WY, Suh GJ, Kim KS, et al. Niacin and Selenium Attenuate Sepsis-Induced Lung Injury by Up-Regulating Nuclear Factor Erythroid 2-Related Factor 2 Signaling[J]. Crit Care Med, 2016, 44(6): e370-382.
[6] Potz BA, Sellke FW, Abid MR. Endothelial ROS and Impaired Myocardial Oxygen Consumption in Sepsis-induced Cardiac Dysfunction[J]. J Intensive Crit Care, 2016, 2(1).
[7] Schortgen F, Asfar P. Update in sepsis and acute kidney injury 2014[J]. Am J Respir Crit Care Med, 2015, 191(11): 1226-1231.
[8] Zhao L, An R, Yang Y, et al. Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling[J]. J Pineal Res, 2015, 59(2): 230-239.
[9] Abraham E, Singer M. Mechanisms of sepsis-induced organ dysfunction[J]. Crit Care Med, 2007, 35(10): 2408-2416.
[10] Fan YW, Jiang SW, Chen JM, et al. A pulmonary source of infection in patients with sepsis-associated acute kidney injury leads to a worse outcome and poor recovery of kidney function[J]. World J Emerg Med, 2020, 11(1): 18-26.
[11] Zhu LL, Zhou Q. Optimal infusion rate in antimicrobial therapy explosion of evidence in the last five years[J]. Infect Drug Resist, 2018, 11: 1105-1117.
[12] Hebbar K, Rigby MR, Felner EI, et al. Neuroendocrine dysfunction in pediatric critical illness[J]. Pediatr Crit Care Med, 2009, 10(1): 35-40.
[13] Irusen E, Matthews JG, Takahashi A, et al. p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma[J]. J Allergy Clin Immunol, 2002, 109(4): 649-657.
[14] Maumus M, Guerit D, Toupet K, et al. Mesenchymal stem cell-based therapies in regenerative medicine: applications in rheumatology[J]. Stem Cell Res Ther, 2011, 2(2): 14.
[15] Zhu F, Guo GH, Chen W, et al. Effects of bone marrow-derived mesenchymal stem cells engraftment on vascular endothelial cell growth factor in lung tissue and plasma at early stage of smoke inhalation injury[J]. World J Emerg Med, 2010, 1(3): 224-228.
[16] Sun CK, Yen CH, Lin YC, et al. Autologous transplantation of adipose-derived mesenchymal stem cells markedly reduced acute ischemia-reperfusion lung injury in a rodent model[J]. J Transl Med, 2011, 9: 118.
[17] Le Blanc K, Tammik L, Sundberg B, et al. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex[J]. Scand J Immunol, 2003, 57(1): 11-20.
[18] Gonzalez-Rey E, Anderson P, Gonzalez MA, et al. Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis[J]. Gut, 2009, 58(7): 929-939.
[19] Gonzalez MA, Gonzalez-Rey E, Rico L, et al. Adipose-derived mesenchymal stem cells alleviate experimental colitis by inhibiting inflammatory and autoimmune responses[J]. Gastroenterology, 2009, 136(3): 978-989.
[20] Nemeth K, Leelahavanichkul A, Yuen PS, et al. Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production[J]. Nat Med, 2009, 15(1): 42-49.
[21] Ikarashi S, Tsuchiya A, Kawata Y, et al. Effects of Human Adipose Tissue-Derived and Umbilical Cord Tissue-Derived Mesenchymal Stem Cells in a Dextran Sulfate Sodium-Induced Mouse Model[J]. Biores Open Access, 2019, 8(1): 185-199.
[22] Taeb AM, Hooper MH, Marik PE. Sepsis: Current Definition, Pathophysiology, Diagnosis, and Management[J]. Nutr Clin Pract, 2017, 32(3): 296-308.
[23] Li D, Wang P, Wang P, et al. The gut microbiota: A treasure for human health[J]. Biotechnol Adv, 2016, 34(7): 1210-1224.
[24] Hooper LV, Macpherson AJ. Immune adaptations that maintain homeostasis with the intestinal microbiota[J]. Nat Rev Immunol, 2010, 10(3): 159-169.
[25] Dorman G, Kocsis-Szommer K, Spadoni C, et al. MMP inhibitors in cardiac diseases: an update[J]. Recent Pat Cardiovasc Drug Discov, 2007, 2(3): 186-194.
[26] Luo JX, Zhang Y, Hu XY. The Effect of Modified Sini Decoction on Survival Rates of Patients with Hepatitis B Virus Related Acute-on-Chronic Liver Failure[J]. 2019, 2019: 2501847.
[27] Stewart CJ, Embleton ND, Marrs ECL, et al. Longitudinal development of the gut microbiome and metabolome in preterm neonates with late onset sepsis and healthy controls[J]. Microbiome, 2017, 5(1): 75.
[28] Haak BW, Prescott HC, Wiersinga WJ. Therapeutic Potential of the Gut Microbiota in the Prevention and Treatment of Sepsis[J]. Front Immunol, 2018, 9: 2042.
[29] West CE, Renz H, Jenmalm MC, et al. The gut microbiota and inflammatory noncommunicable diseases: associations and potentials for gut microbiota therapies[J]. J Allergy Clin Immunol, 2015, 135(1): 3-13; quiz 14.
[30] Klingensmith NJ, Coopersmith CM. The Gut as the Motor of Multiple Organ Dysfunction in Critical Illness[J]. Crit Care Clin, 2016, 32(2): 203-212.
[31] Yoshihisa A. Altered Gut Flora and Gut Microbiome-Derived Metabolites in Heart Failure Patients in the Compensated and Decompensated Phases[J]. Circ J, 2018, 83(1): 30-31.
[32] Ojima M, Motooka D, Shimizu K, et al. Metagenomic Analysis Reveals Dynamic Changes of Whole Gut Microbiota in the Acute Phase of Intensive Care Unit Patients[J]. Dig Dis Sci, 2016, 61(6): 1628-1634.
[33] Rittirsch D, Huber-Lang MS, Flierl MA, et al. Immunodesign of experimental sepsis by cecal ligation and puncture[J]. Nat Protoc, 2009, 4(1): 31-36.
[34] Zhao T, Pan B, Alam HB, et al. Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice[J]. Sci Rep, 2016, 6: 36696.
[35] Ding XF, Sun M, Guan FX, et al. Prenatal Exposure to LPS Alters The Intrarenal RAS in Offspring, Which Is Ameliorated by Adipose Tiss ue-Derived Mesenchymal Stem Cells[J]. Am J Hypertens, 2017, 30(12): 1211-1219.
[36] Logue JB, Stedmon CA, Kellerman AM, et al. Experimental insights into the importance of aquatic bacterial community composition to the degradation of dissolved organic matter[J]. 2016, 10(3): 533-545.
[37] Walters W, Hyde ER, Berg-Lyons D, et al. Improved Bacterial 16S rRNA Gene (V4 and V4-5) and Fungal Internal Transcribed Spacer Marker Gene Primers for Microbial Community Surveys[J]. mSystems, 2016, 1(1).
[38] Takai K, Horikoshi K. Rapid detection and quantification of members of the archaeal community by quantitative PCR using fluorogenic probes[J]. Appl Environ Microbiol, 2000, 66(11): 5066-5072.
[39] Xie J, Liu Y, Chen B, et al. Ganoderma lucidum polysaccharide improves rat DSS-induced colitis by altering cecal microbiota and gene expression of colonic epithelial cells[J]. Food Nutr Res, 2019, 63.
[40] Vega-Magana N, Delgado-Rizo V, Garcia-Benavides L, et al. Bacterial Translocation Is Linked to Increased Intestinal IFN-gamma, IL-4, IL-17, and mucin-2 in Cholestatic Rats[J]. Ann Hepatol, 2018, 17(2): 318-329.
[41] Shogan BD, Smith DP, Christley S, et al. Intestinal anastomotic injury alters spatially defined microbiome composition and function[J]. Microbiome, 2014, 2: 35.
[42] Alam A, Leoni G, Quiros M, et al. The microenvironment of injured murine gut elicits a local pro-restitutive microbiota[J]. 2016, 1: 15021.
[43] Berry D, Stecher B, Schintlmeister A, et al. Host-compound foraging by intestinal microbiota revealed by single-cell stable isotope probing[J]. Proc Natl Acad Sci U S A, 2013, 110(12): 4720-4725.
[44] Zhang Z, Wu X, Cao S, et al. Chlorogenic Acid Ameliorates Experimental Colitis by Promoting Growth of Akkermansia in Mice[J]. Nutrients, 2017, 9(7).
[45] Hu L, Yin C, Zhao F, et al. Mesenchymal Stem Cells: Cell Fate Decision to Osteoblast or Adipocyte and Application in Osteoporosis Treatment[J]. 2018, 19(2).
[46] Lin GL, McGinley JP, Drysdale SB, et al. Epidemiology and Immune Pathogenesis of Viral Sepsis[J]. Front Immunol, 2018, 9: 2147.
[47] Lyons JD, Coopersmith CM. Pathophysiology of the Gut and the Microbiome in the Host Response[J]. Pediatr Crit Care Med, 2017, 18(3_suppl Suppl 1): S46-s49.
[48] Rainer F, Horvath A, Sandahl TD, et al. Soluble CD163 and soluble mannose receptor predict survival and decompensation in patients with liver cirrhosis, and correlate with gut permeability and bacterial translocation[J]. Aliment Pharmacol Ther, 2018, 47(5): 657-664.
[49] Ding XF, Liang HY, Sun JY, et al. Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1[J]. 2019.
[50] Liang H, Ding X, Yu Y, et al. Adipose-derived mesenchymal stem cells ameliorate acute liver injury in rat model of CLP induced-sepsis via sTNFR1[J]. Exp Cell Res, 2019, 383(1): 111465.
[51] Pan H, Guo R, Zhu J, et al. A gene catalogue of the Sprague-Dawley rat gut metagenome[J]. Gigascience, 2018, 7(5).