Known for its sustainable properties, the usability of hemp instead of 100% cotton yarn for clothing was investigated by spinning hybrid ring yarns using cotton, viscose-hemp, and organic cotton-viscose-hemp blends as being the sheath; elastane and polyester (Lycra and T400) as being the core in the yarn structure. Unevenness, yarn imperfection, hairiness, tenacity, and breaking elongation properties of spun yarns produced were examined, comparatively. The findings revealed that sheath fiber type, number of the component in yarn structure, and blend ratio were influential factors on yarn quality. Using hemp fiber in the yarn structure slightly decreased the yarn properties, except tenacity, in general. Moreover, the properties of hemp fiber including triple blended yarn properties were the worst of all. Blending viscose and hemp fibers in the yarn structure provided a synergetic effect, improving the weak properties of both fibers. As a result, since the structural and mechanical features of 70/30% viscose-hemp blended yarns were at an acceptable level, these blended yarns could be suggested in clothing production instead of using 100% cotton for sustainable production.