Performing a computational fluid dynamics (CFD) analysis of a settlement can present many parameters such as determining the wind load, predicting the temperature distribution, determining the turbulence formations about how that settlement should be located, to the scientists in the architectural and engineering departments. In this study, a CFD analysis has been done using a commercial analysis program “Ansys Fluent” and the geometry has been created using an architectural program known as “SketchUp”. Istanbul Health and Technology University Merter Campus buildings have been taken as the reference models. Streamlines, velocity, pressure, temperature and turbulence kinetic energy distribution contours have been projected. The highest flow velocities and turbulence density were observed between the campus buildings, and when the temperature distributions were examined, dramatic decreases were found in the building temperatures on the windward facade. The maximum wind loads, temperature distributions and so on have been detected and according to the results, recommendations have been made.