An ultra-wideband (UWB) fractal antenna based on a new epsilon-shaped geometry is described in this paper for microwave applications in the medical field. The antenna geometry is designed by combining four epsilon shapes and three pairs of straight-line conductors. The new configuration has an impedance bandwidth ranging from 2.58 to 20.95GHz. The size of the designed antenna is 26 mm x 22 mm (0.22λLx 0.19λL) with a wavelength of 116.3mm. For a novel design technique, a reconfigurable patch antenna is proposed for 3.6GHz (Wi-max), 5.4GHz (WLAN), 3.1–10.6 GHz (UWB), and all applications operating in the X band(8–12 GHz) and Ku-band(12–18 GHz). ADS software is applied to configure and validate a comprehensive equivalent circuit model, and CST software is used to perform the full-wave analysis of the proposed antenna. A prototype of the suggested antenna is fabricated on a substrate of FR4 with a height of 1.6mm to confirm the entire wave investigation and the theoretical solution outcomes of the circuit. It is proved that the comparative outcomes of the measurement and simulation have a good agreement. The proposed antenna also provides a high realized gain magnitude of 7.21 dB at an operational frequency of 20.95GHz.