The paper introduces combined Run-Length encoding (RLE) and Huffman encoding approach for image compression. The approach can be applied to the peculiar type of images that satisfies specific characteristics in terms of color components data. The devised approach is supposed to implement lossless compression for the preprocessed image data. First, the RLE is applied to the prepared data, then, Huffman coding process is performed. The results received during the test session of the implemented software showcase that the proposed technique is feasible and provides a decent level of compression. It can be implemented also in the hardware since the complexity of the operations used is relatively low.