Sandblasting is a standard procedure used for treating the implant surface to enhance the osseointegration with known clinical success. This retrospective cohort study aimed to evaluate the long-term clinical outcomes of sandblasted implants. Two hundred fifty-five MG Osseous screw implants were placed in 81 patients using a two-stage surgical technique and conventional loading protocol (three-months). Implant and prosthetic clinical findings were evaluated during a 15-years follow-up. Four implants were lost during the healing period, and 103 fixed prostheses were placed over the 251 implants left: 58 single-crowns, 31 partially fixed bridges, and 14 full-arch fixed restorations. Fourteen implants were lost during the follow-up period. Clinical results indicated an implant survival rate of 92.9%. 11.8% of implants showed peri-implantitis as the primary biological complication. The mean marginal bone loss was 1.76 ± 0.38 mm, ranging from 0.9 to 2.8 mm. The most frequent complication was mechanical prosthodontic complications (20.9%). Sandblasted surface implants inserted in both maxillary and mandibular areas produce favorable outcomes and stable tissue conditions when a delayed loading protocol is followed.