This study was carried out retrospectively as a case-control study at Al-Zhrawi Hospital between January 1 and May 1, 2022. The study received approval from the local ethics commission. This study has 200 participants. There were 60 patients in the PE group and 140 individuals in the control group. Patients in their third trimester who were followed up on and treated at our hospital but did not have PE or systemic illness were randomly chosen to make up the control group.
Diagnosing criteria of PE was based on criteria of the American College of Obstetrics and Gynecology in 2013 [10]. They were: Blood pressure ≥ 140 mmHg systolic or 90 mmHg diastolic on two occasions at least 4 h apart after 20 weeks of gestation with a previously normal blood pressure or blood pressure ≥ 160 mmHg systolic or ≥ 110mmHg diastolic and proteinuria (dipstick reading of 1+, protein/creatinine ratio ≥ 0.3, or ≥ 0.3 g in a 24 h urine specimen) or in the absence of proteinuria, new‑onset hypertension with the new onset of any of the following: thrombocytopenia (Platelet count ≤ 100,000/mlt), renal insufficiency serum creatinine concentrations ≥ 1.1mg/dl, elevated blood concentrations of liver transaminases to twice normal concentration, pulmonary edema, and cerebral visual symptoms.
Patients with active local or systemic infection, chorioamnionitis, diabetes mellitus, nephropathy, renal or hepatic dysfunction, or who were taking any medication like corticosteroids at the time of the trial were not eligible. Patients who had any indications or symptoms of an infection that was actively spreading (pain, fever, or vaginal discharge) were not included in the research. Before beginning any medical care, serum samples for complete blood counts with differentials such as neutrophil leukocyte, platelets, NLR, PLR, and MPV were taken from patients upon admission to the emergency room.
While categorical variables were shown as percentages and proportions, continuous variables were summarized as mean and standard deviation (SD). In contrast to the t-test, which was used to compare continuous variables, the chi-square test was used to compare categorical variables. The p-value was set at 0.05, which is statistically significant. Software called JMP Pro 14 was used for all statistical analyses (JMP, Pro 14, SAS Institute Inc., Cary, NC, 1989–2019).