Found in fibroblasts of all donor groups | | |
| extracellular structure organization | extracellular matrix organization | system development |
| system development | extracellular structure organization | extracellular structure organization |
| extracellular matrix organization | system development | multicellular organism development |
| multicellular organism development | multicellular organism development | anatomical structure development |
| anatomical structure development | anatomical structure development | extracellular matrix organization |
N2+/N0 | | |
| response to oxidative stress | coronary vasculature morphogenesis | regulation of body fluid levels |
| response to reactive oxygen species | response to reactive oxygen species | heart process |
| cardiocyte differentiation | receptor-mediated virion attachment to host cell | dermatan sulphate metabolic process |
| cellular response to ketone | male sex differentiation | response to hydrogen peroxide |
| reactive oxygen species metabolic process | cellular response to amino acid stimulus | renal system process |
| organ growth | plasma membrane bounded cell projection organization | smooth muscle contraction |
| male sex differentiation | cell projection organization | phosphorylation |
| telencephalon development | protein kinase B signalling | |
| glomerulus vasculature development | blastoderm segmentation | |
| renal system vasculature development | | |
N1/N0 | | |
| heterotypic cell-cell adhesion | actin filament bundle assembly | ear development |
| response to fluid shear stress | response to fluid shear stress | inner ear development |
| regulation of morphogenesis of a branching structure | cellular response to toxic substance | substrate-dependent cell migration |
| positive chemotaxis | cellular response to fluid shear stress | reactive oxygen species metabolic process |
| female sex differentiation | glycoprotein metabolic process | cellular aldehyde metabolic process |
| positive regulation of actin filament bundle assembly | glomerulus morphogenesis | decidualization |
| cellular response to extracellular stimulus | acid secretion | cellular detoxification |
| actin filament bundle assembly | cellular detoxification | positive regulation of developmental growth |
| actin filament bundle organization | | embryo implantation |
| contractile actin filament bundle assembly | | |
N2+/N1 | | |
| embryo implantation | sulphur compound metabolic process | myeloid leukocyte activation |
| maternal placenta development | regulation of plasma lipoprotein particle levels | fibroblast proliferation |
| regulation of cell size | maternal process involved in female pregnancy | regulation of fibroblast proliferation |
| maintenance of location | arachidonic acid metabolic process | myeloid leukocyte mediated immunity |
| limb bud formation | maternal placenta development | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
| facial nerve morphogenesis | endothelial cell fate commitment | digestive system development |
| heart process | hypothalamus cell migration | digestive tract development |
| heart contraction | gonadotrophin-releasing hormone neuronal migration to the hypothalamus | sulphur compound biosynthetic process |
| fibroblast proliferation | branching involved in salivary gland morphogenesis | |
| inflammatory response to wounding | | |
Unique in N0 | | |
| response to dexamethasone | cellular response to oxidative stress | response to fluid shear stress |
| cellular response to toxic substance | heart growth | cellular response to fluid shear stress |
| response to hydrogen peroxide | adhesion of symbiont to host | nitric oxide biosynthetic process |
| cell recognition | positive regulation of cell division | nitric oxide metabolic process |
| cellular response to oxidative stress | cardiac muscle cell differentiation | reactive nitrogen species metabolic process |
Unique in N1 | | |
| regulation of extracellular matrix organization | regulation of prostatic bud formation | immune effector process |
| response to vitamin D | isopentenyl diphosphate biosynthetic process | heart valve development |
| replicative senescence | isopentenyl diphosphate metabolic process | actin filament bundle assembly |
| placenta blood vessel development | plasma lipoprotein particle clearance | heart valve morphogenesis |
| basement membrane organization | collagen-activated signalling pathway | regulation of supramolecular fibre organization |
Unique in N2+ | | |
| metanephric glomerulus development | sympathetic neuron projection guidance | cellular ketone metabolic process |
| metanephric glomerulus vasculature development | trunk segmentation | protein metabolic process |
| sympathetic neuron projection guidance | sympathetic neuron projection extension | ossification involved in bone maturation |
| keratinocyte development | trigeminal nerve morphogenesis | hormone biosynthetic process |
| multicellular organismal reproductive process | trigeminal nerve structural organization | mammary gland development |
N0 = fibroblasts of cancer-free donors, |
N1 = fibroblasts of long-term survivors of childhood cancer without a second primary neoplasm, |
N2 + = fibroblasts of long-term survivors of childhood cancer with at least one second primary neoplasm |
Where the top 5 terms per comparison were not identical with regard to the p-values of the compared groups, more than 5 terms may be shown. |