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Research Article
Clinical features in mild type and severe type of COVID-19 patients
Liang Peng
Third Affiliated Hospital of Sun Yat-Sen University
Corresponding Author
ORCiD: https://orcid.org/0000-0001-6184-5750
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Coronavirus Disease 2019 (COVID-19) outbroke in Wuhan and spread to the world quickly. We aim to describe the clinical features and compare them between mild type and severe type of COVID-19 patients.
Methods: Laboratory confirmed COVID-19 patients were included in this study. Patients’ demographic data and clinical features were recorded and compared between mild type and severe type.
Results: Fifteen patients were confirmed COVID-19 and enrolled in this study. Six patients were of mild type, while 9 patients were of severe type. Statistical differences were found between mild type and severe type patients in retirement, epidemiological history, baseline blood level of lactate dehydrogenase and Oxygenation Index (All p < 0.05). All patients had ground-glass opacities without consolidation in initial chest computed tomography images, 2 (16.7%) patients had pulmonary nodules. There were no statistical differences between mild type and severe type patients in initial chest CT findings (All p > 0.05).
Conclusions: Differences can be found in baseline clinical features between mild type and severe type of COVID-19 patients to help health care providers making early judgement to the severity and proper treatment.
Trial registration: The study was registered in ClinicalTrials.gov, NCT04279782. Registered 20 February 2020 - Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT04279782?term=NCT04279782&draw=2&rank=1
Keywords
coronavirus, COVID-19, computed tomography, severity
Figure 1
John Lambiase
commented on 19 April, 2020
Why no Vitamin D Status, knowing about it's potential role in "Innate and Adaptive immunity(1)" and how prevalent Vitamin D Deficiency is in Northern Italy in Eldery (2). (1)https://www.sciencedirect.com/science/article/pii/B9780123869609000022?via%3Dihub (2)https://www.ncbi.nlm.nih.gov/pubmed/25948029
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This is a preprint. It has not completed peer review.
Research Article
Clinical features in mild type and severe type of COVID-19 patients
Liang Peng
Third Affiliated Hospital of Sun Yat-Sen University
Corresponding Author
ORCiD: https://orcid.org/0000-0001-6184-5750
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 15 Apr, 2020
Community comments: 1
Metrics
Comments: 1
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Coronavirus Disease 2019 (COVID-19) outbroke in Wuhan and spread to the world quickly. We aim to describe the clinical features and compare them between mild type and severe type of COVID-19 patients.
Methods: Laboratory confirmed COVID-19 patients were included in this study. Patients’ demographic data and clinical features were recorded and compared between mild type and severe type.
Results: Fifteen patients were confirmed COVID-19 and enrolled in this study. Six patients were of mild type, while 9 patients were of severe type. Statistical differences were found between mild type and severe type patients in retirement, epidemiological history, baseline blood level of lactate dehydrogenase and Oxygenation Index (All p < 0.05). All patients had ground-glass opacities without consolidation in initial chest computed tomography images, 2 (16.7%) patients had pulmonary nodules. There were no statistical differences between mild type and severe type patients in initial chest CT findings (All p > 0.05).
Conclusions: Differences can be found in baseline clinical features between mild type and severe type of COVID-19 patients to help health care providers making early judgement to the severity and proper treatment.
Trial registration: The study was registered in ClinicalTrials.gov, NCT04279782. Registered 20 February 2020 - Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT04279782?term=NCT04279782&draw=2&rank=1
Figure 1
John Lambiase
commented on 19 April, 2020
Why no Vitamin D Status, knowing about it's potential role in "Innate and Adaptive immunity(1)" and how prevalent Vitamin D Deficiency is in Northern Italy in Eldery (2). (1)https://www.sciencedirect.com/science/article/pii/B9780123869609000022?via%3Dihub (2)https://www.ncbi.nlm.nih.gov/pubmed/25948029