Suppression is assessed using a variety of methods with different stimuli that vary in color, contrast, size, and luminance. We hypothesized that stimulus variation may yield different spatial extents of suppression. Here, to evaluate the role of stimulus characteristics, we measured the suppression zone using a binocular rivalry paradigm in normal observers by systematically varying the parameters of dichoptic Difference of Gaussian stimuli. The stimuli consist of a constantly visible horizontal reference seen by one eye while two vertical suppressors were presented to the other eye. With a keypress, the suppressors appeared for 1 second, to induce a robust transient suppression zone in the middle part of the reference. Subjects adjusted the width between the suppressors to determine the zone. The zone decreased significantly with increasing spatial frequency and lower contrast. The horizontal zone was larger than the vertical zone by a factor of 1.4. The zone was smaller with negative contrast stimuli compared to positive contrast polarity but independent of eye dominance, luminance and colored filters. We then fit a model to determine the optimal parametric definition of the suppression zone and found that the zone consists of two parts: a stimulus-dependent and a fixed non-stimulus dependent zone.