Continuous passive motion (CPM) has become an adjunct therapy to the standard postoperative rehabilitation regimen of joint injuries for a long time. However, the ability to in real-time monitor leg bearing capacity and actual bending angle of knee joints is highly desired for the treatment strategies of personalized postoperative rehabilitation and telemedicine. Here we report a novel intelligent CPM system for personalized rehabilitation and telemedicine based on the flexible and versatile ionotronic that possesses excellent mechanical properties and brilliant environmental tolerance. Especially, the corresponding ionotronic responds fastly and shows excellent cycling stability for strain sensing, ensuring the detection of actual joint bending angle with a high sensitivity and reliability. An intelligent CPM system assembled with this ionotronic and a wireless transmitter was constructed, opening up a new horizon for developing digital intelligent medical that can remotely monitor the movement of hospitalized/at-home patients who use CPM for personalized postoperative rehabilitation.