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Research Article
Wenbo Liao
Affiliated Hospital of Zunyi Medical College
Corresponding Author
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Background: Short-segment transpedicular screw fixation is a common method for the treatment of thoracolumbar burst fractures (TBFs),but this technique has many problems.Therefore,the purpose of this article is to observe and evaluate the clinical efficacy of a new type of transpedicular reducer that we designed for fractured vertebral body reduction and bone grafting in the treatment of TBFs.
Methods:From July 2018 to November 2020, 70 cases of TBFs were included. 35 cases were treated with the new transpedicular reducer for fracture reduction via pedicle and bone grafting combined with pedicle screw fixation (observation group), 35 cases were treated with short-segment transpedicular screw fixation (control group).Before operation, after application of the transpedicular reducer(not needed in the control group),3 days after operation, 3 months after operation, 6 months after operation, and 12 months after operation, the two groups were recorded and compared respectively: the anterior and middle heights of the injured vertebrae, the ratios of the anterior and middle heights of the injured vertebral body to the respective heights of the adjacent uninjured vertebral bodies (AVBHr and MVBHr, respectively), and the Cobb angle of patients.And we compared the pain VAS score and quality of life GQOL-74 score at the last follow-up.At last,we evaluated the distribution of bone grafts and bone healing 12 months after the operation.
Results:All 70 cases were followed up for at least 12 months.The observation group's anterior and middle heights of the injured vertebral, AVBHr and MVBHr were higher than those of the control group at 3 days,3 months,6 months and 12 months after operation, the cobb angle was smaller than that in control group, the pain VAS score and the quality of life GQOL-74 score at the last follow-up were better than those of the control group, and these difference were statistically significant (P <0.05). The observation group showed no obvious defects on CT at 12 months after operation, and the bone healing was good.
Conclusion: The new type of transpedicular reducer for fracture reduction via pedicle and bone grafting combined with pedicle screw fixation for TBFs has a good clinical efficacy.
Keywords
burst fracture, thoracolumbar spine, transpedicular reducer, allogeneic bone, minimally invasive spine surgery
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No competing interests reported.
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CURRENT STATUS: Under Revision
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Posted 10 Mar, 2021
No community comments so far
Editorial decision: Major revision
On 25 Mar, 2021
Review #2 received
Received 17 Mar, 2021
Review #1 received
Received 17 Mar, 2021
Review #4 received
Received 17 Mar, 2021
Review #5 received
Received 17 Mar, 2021
Review #7 received
Received 17 Mar, 2021
Review #3 received
Received 17 Mar, 2021
Review #6 received
Received 17 Mar, 2021
Review #8 received
Received 17 Mar, 2021
Reviewer #3 agreed
On 17 Mar, 2021
Reviewer #5 agreed
On 17 Mar, 2021
Reviewer #6 agreed
On 17 Mar, 2021
Reviewer #8 agreed
On 17 Mar, 2021
Reviewer #7 agreed
On 17 Mar, 2021
Reviewer #9 agreed
On 17 Mar, 2021
Reviewer #19 agreed
On 16 Mar, 2021
Reviewer #22 agreed
On 16 Mar, 2021
Reviewer #20 agreed
On 16 Mar, 2021
Reviewer #21 agreed
On 16 Mar, 2021
Reviewer #4 agreed
On 14 Mar, 2021
Reviewer #28 agreed
On 14 Mar, 2021
Reviewer #2 agreed
On 14 Mar, 2021
Reviewer #27 agreed
On 14 Mar, 2021
Reviewer #30 agreed
On 14 Mar, 2021
Reviewer #23 agreed
On 14 Mar, 2021
Reviewer #31 agreed
On 14 Mar, 2021
Reviewer #33 agreed
On 14 Mar, 2021
Reviewer #26 agreed
On 14 Mar, 2021
Reviewer #24 agreed
On 14 Mar, 2021
Reviewer #29 agreed
On 14 Mar, 2021
Reviewer #32 agreed
On 14 Mar, 2021
Reviewer #34 agreed
On 14 Mar, 2021
Reviewer #25 agreed
On 14 Mar, 2021
Reviewer #1 agreed
On 14 Mar, 2021
Reviewers invited
Invitations sent on 08 Mar, 2021
Editor assigned
On 08 Mar, 2021
Editor invited
On 08 Mar, 2021
Submission checks complete
On 08 Mar, 2021
First submitted
On 16 Feb, 2021
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Subject Areas
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This preprint is under consideration at BMC Musculoskeletal Disorders. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Wenbo Liao
Affiliated Hospital of Zunyi Medical College
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Revision
Version 1
Posted 10 Mar, 2021
No community comments so far
Editorial decision: Major revision
On 25 Mar, 2021
Review #2 received
Received 17 Mar, 2021
Review #1 received
Received 17 Mar, 2021
Review #4 received
Received 17 Mar, 2021
Review #5 received
Received 17 Mar, 2021
Review #7 received
Received 17 Mar, 2021
Review #3 received
Received 17 Mar, 2021
Review #6 received
Received 17 Mar, 2021
Review #8 received
Received 17 Mar, 2021
Reviewer #3 agreed
On 17 Mar, 2021
Reviewer #5 agreed
On 17 Mar, 2021
Reviewer #6 agreed
On 17 Mar, 2021
Reviewer #8 agreed
On 17 Mar, 2021
Reviewer #7 agreed
On 17 Mar, 2021
Reviewer #9 agreed
On 17 Mar, 2021
Reviewer #19 agreed
On 16 Mar, 2021
Reviewer #22 agreed
On 16 Mar, 2021
Reviewer #20 agreed
On 16 Mar, 2021
Reviewer #21 agreed
On 16 Mar, 2021
Reviewer #4 agreed
On 14 Mar, 2021
Reviewer #28 agreed
On 14 Mar, 2021
Reviewer #2 agreed
On 14 Mar, 2021
Reviewer #27 agreed
On 14 Mar, 2021
Reviewer #30 agreed
On 14 Mar, 2021
Reviewer #23 agreed
On 14 Mar, 2021
Reviewer #31 agreed
On 14 Mar, 2021
Reviewer #33 agreed
On 14 Mar, 2021
Reviewer #26 agreed
On 14 Mar, 2021
Reviewer #24 agreed
On 14 Mar, 2021
Reviewer #29 agreed
On 14 Mar, 2021
Reviewer #32 agreed
On 14 Mar, 2021
Reviewer #34 agreed
On 14 Mar, 2021
Reviewer #25 agreed
On 14 Mar, 2021
Reviewer #1 agreed
On 14 Mar, 2021
Reviewers invited
Invitations sent on 08 Mar, 2021
Editor assigned
On 08 Mar, 2021
Editor invited
On 08 Mar, 2021
Submission checks complete
On 08 Mar, 2021
First submitted
On 16 Feb, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Orthopedics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Short-segment transpedicular screw fixation is a common method for the treatment of thoracolumbar burst fractures (TBFs),but this technique has many problems.Therefore,the purpose of this article is to observe and evaluate the clinical efficacy of a new type of transpedicular reducer that we designed for fractured vertebral body reduction and bone grafting in the treatment of TBFs.
Methods:From July 2018 to November 2020, 70 cases of TBFs were included. 35 cases were treated with the new transpedicular reducer for fracture reduction via pedicle and bone grafting combined with pedicle screw fixation (observation group), 35 cases were treated with short-segment transpedicular screw fixation (control group).Before operation, after application of the transpedicular reducer(not needed in the control group),3 days after operation, 3 months after operation, 6 months after operation, and 12 months after operation, the two groups were recorded and compared respectively: the anterior and middle heights of the injured vertebrae, the ratios of the anterior and middle heights of the injured vertebral body to the respective heights of the adjacent uninjured vertebral bodies (AVBHr and MVBHr, respectively), and the Cobb angle of patients.And we compared the pain VAS score and quality of life GQOL-74 score at the last follow-up.At last,we evaluated the distribution of bone grafts and bone healing 12 months after the operation.
Results:All 70 cases were followed up for at least 12 months.The observation group's anterior and middle heights of the injured vertebral, AVBHr and MVBHr were higher than those of the control group at 3 days,3 months,6 months and 12 months after operation, the cobb angle was smaller than that in control group, the pain VAS score and the quality of life GQOL-74 score at the last follow-up were better than those of the control group, and these difference were statistically significant (P <0.05). The observation group showed no obvious defects on CT at 12 months after operation, and the bone healing was good.
Conclusion: The new type of transpedicular reducer for fracture reduction via pedicle and bone grafting combined with pedicle screw fixation for TBFs has a good clinical efficacy.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
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