Crohn’s disease causes chronic inflammation of the gastrointestinal (GI) tract Although its cause is not fully understood, abnormal activation of the GI immune system toward the gut microbiota could be playing a role
In addition, the high number of pro-inflammatory bacteria found in the intestinal microbiota of Crohn’s patients could be triggering this abnormal immune response
A recent pilot trial is the first to evaluate the use of Fecal Microbiota Transplantation (FMT) in maintaining remission in Crohn’s patients
The authors found a higher rate of steroid-free remission in Crohn’s patients treated with FMT
As well as improved lesions and inflammatory biomarkers
Although further studies on a larger patient population are needed
The results of this pilot trial are promising for the many patients suffering from Crohn’s disease.