In this study, the nonisothermal differential scanning calorimetry (DSC) was carried out to evaluate the curing reaction of fiber/epoxy laminates. The optimal curing process of the prepreg was obtained by T-β extrapolation method and nth-order reaction curing kinetic equation. The bending strength, impact strength and thermodynamic properties of the composite laminates with different ply orientations were investigated, respectively. The results show that the apparent activation energy and the reaction order of the prepregs are 82.89 kJ/mol and 0.92, respectively. The curing process of carbon fiber/epoxy resin prepreg is 130 ℃ /60min + 160 ℃/30 min. The bending strength of 10 laminate is 1948.3 MPa, which is 11.8 times higher than that of [+ 45/-45]5s laminate, and 96.4% higher than that of [0/90]5s laminate. The impact strength of 10 laminate is higher than that of [+ 45/-45]5s and [0/90]5s laminates. The glass transition temperature (Tg) of the laminates is 142 ~ 146 ℃, and the loss factor of 10 laminate is significantly higher than that of [+ 45/-45]5s and [0/90]5s laminates. This research provides a theoretical basis for the further application of prepregs to fiber composite materials.