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Research
yang shen
the first hospital of Chongqing Medical University
Corresponding Author
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Background The prevalence of allergic rhinitis (AR) has increased globally. This study was conducted to investigate the changing trends of AR’ s outpatient visits and inhaled allergens, also the possible association between air pollution and AR visits in Chongqing, China.
Methods We analyzed all the skin prick test results from patients diagnosed as AR in Departments of Otolaryngology of the first affiliated hospital of Chongqing Medical University during 2008 to 2017. The trend of AR visit rate and inhaled allergens was observed. Then, air quality data were acquired from the Chongqing Municipal Environmental Protection Monitoring Center. We explored the effects of air pollutants (SO2, NO2, PM2.5, PM10, CO and O3) on outpatient visits for AR.
Results From 2008 to 2017, the ratio of AR outpatient visits increased. The number of polysensitization was more than that of monosensitization. However, the rate of mono-specific sensitization to dust mite allergen was on the increase, especially in patients of 20–39 y. No correlations were found between AR visits and pollutants, while mono-mite-sensitized AR visits were significantly correlated with the concentrations of atmospheric SO2, PM10 and PM2.5.
Conclusions the rising trends in AR visits reflect both a real increase in the occurrence and a more effective diagnosis of cases. Increment in mono-mite sensitization implies the rising trends of new AR cases. The significant correlation between mono-mite-sensitized AR visits and concentration of SO2, PM10 and PM2.5 supports opinion about an influence of atmospheric pollutants on mite induced immune response in AR.
Keywords
allergic rhinitis, outpatient visit, allergen, skin prick test, air pollution
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This is a preprint. It has not completed peer review.
Research
yang shen
the first hospital of Chongqing Medical University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 13 May, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Allergy & Immune Disorders
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background The prevalence of allergic rhinitis (AR) has increased globally. This study was conducted to investigate the changing trends of AR’ s outpatient visits and inhaled allergens, also the possible association between air pollution and AR visits in Chongqing, China.
Methods We analyzed all the skin prick test results from patients diagnosed as AR in Departments of Otolaryngology of the first affiliated hospital of Chongqing Medical University during 2008 to 2017. The trend of AR visit rate and inhaled allergens was observed. Then, air quality data were acquired from the Chongqing Municipal Environmental Protection Monitoring Center. We explored the effects of air pollutants (SO2, NO2, PM2.5, PM10, CO and O3) on outpatient visits for AR.
Results From 2008 to 2017, the ratio of AR outpatient visits increased. The number of polysensitization was more than that of monosensitization. However, the rate of mono-specific sensitization to dust mite allergen was on the increase, especially in patients of 20–39 y. No correlations were found between AR visits and pollutants, while mono-mite-sensitized AR visits were significantly correlated with the concentrations of atmospheric SO2, PM10 and PM2.5.
Conclusions the rising trends in AR visits reflect both a real increase in the occurrence and a more effective diagnosis of cases. Increment in mono-mite sensitization implies the rising trends of new AR cases. The significant correlation between mono-mite-sensitized AR visits and concentration of SO2, PM10 and PM2.5 supports opinion about an influence of atmospheric pollutants on mite induced immune response in AR.
Figure 1
Figure 2
Figure 3
Figure 4
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